200020329

MPZ Monoclonal Antibody (C13), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

MPZ

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

Charcot-Marie-Tooth neuropathy 1B, CHM, CMT1, CMT1B, CMT2I, CMT2J, CMT4E, CMTDI3, CMTDID, DSS, HMSNIB, MPP, MPZ, Myelin peripheral protein, myelin protein P0, Myelin protein zero, myelin protein zero (Charcot-Marie-Tooth neuropathy 1B), P0, P-zero

Gene Symbols

MPZ

Isotype

IgG3 κ

Purification Method

Protein A/G

Gene

MPZ

Clone

C13

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human, Mouse, Porcine, Rat

Gene Accession No.

P06907, P25189, P27573

Gene ID (Entrez)

100153273, 17528, 24564, 4359

Immunogen

Recombinant Human MPZ protein, Ile30-Lys248 (Accession #P25189)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Description

  • Zero, also known as myelin protein zero (MPZ) is a Type 1 integral membrane glycoprotein that mediates adhesion of spiraling wraps of the myelin sheath in order to ensure stable synaptic transmission
  • Zero protein encompasses approximately 50% of total protein in the sheath scaffolding in contribution to structural integrity of peripheral myelin
  • Zero guides the compact myelin wrapping process through glycine zipper packing interface-dependent dimer and tetramer formation
  • Mutations (e.g
  • G134R) can abrogate multimer formation, cause demyelinating neuropathies, and are known to contribute to conditions that include Charcot-Marie-Tooth disease
  • Zero cytoplasmic domain undergoes serine and tyrosine phosphorylation, which appears to be prevalent during peak nerve myelination
  • Zero transcript is moderate in brain, abundant in thymus and most abundant in white matter of the CNS.

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Fischer Scientific

200020329

Mouse Monoclonal Antibody...


Antigen:
MPZ

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
Charcot-Marie-Tooth neuropathy 1B, CHM, CMT1, CMT1B, CMT2I, CMT2J, CMT4E, CMTDI3, CMTDID, DSS, HMSNIB, MPP, MPZ, Myelin peripheral protein, myelin protein P0, Myelin protein zero, myelin protein zero (Charcot-Marie-Tooth neuropathy 1B), P0, P-zero

Gene Symbols:
MPZ

Isotype:
IgG3 κ

Purification Method:
Protein A/G

Gene:
MPZ

Clone:
C13

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Mouse, Porcine, Rat

Gene Accession No.:
P06907, P25189, P27573

Gene ID (Entrez):
100153273, 17528, 24564, 4359

Immunogen:
Recombinant Human MPZ protein, Ile30-Lys248 (Accession #P25189)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Fischer Scientific

200020330

Rabbit Polyclonal Antibody...


Antigen:
Trypsin

Concentration:
0.5 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
Alpha-trypsin chain 1, Alpha-trypsin chain 2, Anionic trypsin I, anionic trypsin-1, Anionic trypsinogen, beta-trypsin, Cationic trypsinogen, digestive zymogen, MGC120175, MGC149362, nonfunctional trypsin 1, pancreatic trypsin 1, pretrypsinogen I, Protease Serine 1, protease serine 2 preproprotein, protease, serine 1, protease, serine 1 (trypsin 1), protease, serine 2, protease, serine, 1, protease, serine, 1 (trypsin 1), protease, serine, 2, protease, serine, 2 (trypsin 2), PRSS1, PRSS2, PTRYI, RATPTRYI, Serine protease 1, Serine protease 2, TCR V beta 4.1, TRP1, Try1, Try-1, TRY2, TRY4, TRY8, Trygn16, TRYP1, TRYP2, TRYP8, trypsin 1, Trypsin I, Trypsin II, trypsin-1, Trypsin-2, trypsinogen, trypsinogen 1, trypsinogen 16, trypsinogen 2, trypsinogen A

Gene Symbols:
PRSS1

Isotype:
IgG

Purification Method:
Protein A

Gene:
PRSS1

Clone:
__

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse, Porcine, Rat

Gene Accession No.:
P00762, P07477

Gene ID (Entrez):
114228, 24691, 5644

Immunogen:
Recombinant Human PRSS1 protein, Ser51-Val228 (Accession #P07477)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Fischer Scientific

200020331

Mouse Monoclonal Antibody...


Antigen:
LRP1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
A2MR, AI316852, alpha 2-macroglobulin receptor, alpha-2-macroglobulin receptor, APOER, Apolipoprotein E receptor, APR, b2b1554Clo, CD91, FLJ16451, IGFBP3R, LDL receptor related protein 1, lipoprotein receptor-related protein, low density lipoprotein receptor-related protein 1, low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor), Low-density lipoprotein receptor-related protein 1 515 kDa subunit, Low-density lipoprotein receptor-related protein 1 85 kDa subunit, Low-density lipoprotein receptor-related protein 1 intracellular domain, Lrp, Lrp1, LRP-1, LRP1A, LRP-515, LRP-85, LRPICD, MGC88725, Prolow-density lipoprotein receptor-related protein 1, TbetaR-V/LRP-1/IGFBP-3 receptor, TGFBR5, type V tgf-beta receptor

Gene Symbols:
LRP1

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
LRP1

Clone:
D3

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Rat

Gene Accession No.:
Q07954

Gene ID (Entrez):
299858, 4035

Immunogen:
Recombinant Human LRP1 protein, Val4441-Ala4544 (Accession #Q07954)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Img

Fischer Scientific

200020331

Mouse Monoclonal Antibody...


Antigen:
LRP1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
A2MR, AI316852, alpha 2-macroglobulin receptor, alpha-2-macroglobulin receptor, APOER, Apolipoprotein E receptor, APR, b2b1554Clo, CD91, FLJ16451, IGFBP3R, LDL receptor related protein 1, lipoprotein receptor-related protein, low density lipoprotein receptor-related protein 1, low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor), Low-density lipoprotein receptor-related protein 1 515 kDa subunit, Low-density lipoprotein receptor-related protein 1 85 kDa subunit, Low-density lipoprotein receptor-related protein 1 intracellular domain, Lrp, Lrp1, LRP-1, LRP1A, LRP-515, LRP-85, LRPICD, MGC88725, Prolow-density lipoprotein receptor-related protein 1, TbetaR-V/LRP-1/IGFBP-3 receptor, TGFBR5, type V tgf-beta receptor

Gene Symbols:
LRP1

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
LRP1

Clone:
D3

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Rat

Gene Accession No.:
Q07954

Gene ID (Entrez):
299858, 4035

Immunogen:
Recombinant Human LRP1 protein, Val4441-Ala4544 (Accession #Q07954)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.