200020298

CD279 (PD-1) Monoclonal Antibody (eBioJ105 (J105)), Brilliant Ultra Violet™ 615, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

CD279 (PD-1)

Concentration

5 μL/Test

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias

CD279, EGK_05005, hPD1, hPD-1, hPD-l, hSLE1, Ly101, mPD-1, PD1, PD-1, Pdc1, Pdcd1, programmed cell death 1, programmed cell death 1 protein, programmed cell death protein 1, programmed cell death protein 1-like, programmed death 1, Protein PD1, protein PD-1, sCD279, SLEB2, soluble CD279, systemic lupus erythematosus susceptibility 2

Gene Symbols

Pdcd1

Primary or Secondary

Primary

Content And Storage

4°, C, store in dark, DO NOT FREEZE!

Clone

eBioJ105 (J105)

Applications

Flow Cytometry

Conjugate

Brilliant Ultraviolet 615

Host Species

Mouse

Target Species

Human, Rhesus Monkey

Gene Accession No.

Q15116

Gene ID (Entrez)

100135775, 5133

Isotype

IgG1 κ

Purification Method

Affinity chromatography

Gene

Pdcd1

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Description

  • Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC)
  • T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC
  • PD-1 can bind two different but related ligands, PDL-1 and PDL-2
  • Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of &quotedanger signals&quote such as LPS or other molecules associated with bacteria or other pathogens
  • Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases
  • Despite its predicted molecular weight, PD-1 often migrates at higher molecular weight in SDS-PAGE.

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Img

Fischer Scientific

200020298

Mouse Monoclonal Antibody...


Antigen:
CD279 (PD-1)

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
CD279, EGK_05005, hPD1, hPD-1, hPD-l, hSLE1, Ly101, mPD-1, PD1, PD-1, Pdc1, Pdcd1, programmed cell death 1, programmed cell death 1 protein, programmed cell death protein 1, programmed cell death protein 1-like, programmed death 1, Protein PD1, protein PD-1, sCD279, SLEB2, soluble CD279, systemic lupus erythematosus susceptibility 2

Gene Symbols:
Pdcd1

Primary or Secondary:
Primary

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Clone:
eBioJ105 (J105)

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 615

Host Species:
Mouse

Target Species:
Human, Rhesus Monkey

Gene Accession No.:
Q15116

Gene ID (Entrez):
100135775, 5133

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Gene:
Pdcd1

Img

Fischer Scientific

200020299

Mouse Monoclonal Antibody...


Antigen:
CD279 (PD-1)

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
CD279, EGK_05005, hPD1, hPD-1, hPD-l, hSLE1, Ly101, mPD-1, PD1, PD-1, Pdc1, Pdcd1, programmed cell death 1, programmed cell death 1 protein, programmed cell death protein 1, programmed cell death protein 1-like, programmed death 1, Protein PD1, protein PD-1, sCD279, SLEB2, soluble CD279, systemic lupus erythematosus susceptibility 2

Gene Symbols:
Pdcd1

Primary or Secondary:
Primary

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Clone:
eBioJ105 (J105)

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 421

Host Species:
Mouse

Target Species:
Human, Rhesus Monkey

Gene Accession No.:
Q15116

Gene ID (Entrez):
100135775, 5133

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Gene:
Pdcd1

Img

Fischer Scientific

200020301

Mouse Monoclonal Antibody...


Antigen:
CD279 (PD-1)

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
CD279, EGK_05005, hPD1, hPD-1, hPD-l, hSLE1, Ly101, mPD-1, PD1, PD-1, Pdc1, Pdcd1, programmed cell death 1, programmed cell death 1 protein, programmed cell death protein 1, programmed cell death protein 1-like, programmed death 1, Protein PD1, protein PD-1, sCD279, SLEB2, soluble CD279, systemic lupus erythematosus susceptibility 2

Gene Symbols:
Pdcd1

Primary or Secondary:
Primary

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Clone:
eBioJ105 (J105)

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 650

Host Species:
Mouse

Target Species:
Human, Rhesus Monkey

Gene Accession No.:
Q15116

Gene ID (Entrez):
100135775, 5133

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Gene:
Pdcd1

Img

Fischer Scientific

200020302

Rabbit Polyclonal Antibody...


Antigen:
HEPH

Concentration:
0.5 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
C130006F04Rik, Cpl, haphaestin, Heph, Hephaestin, KIAA0698, mKIAA0698, sex linked anemia, sla, UNQ2562/PRO6242

Gene Symbols:
HEPH

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Clone:
__

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
Q9BQS7, Q9Z0Z4

Gene ID (Entrez):
15203, 9843

Isotype:
IgG

Purification Method:
Protein A

Gene:
HEPH