200020332
CD279 (PD-1) Monoclonal Antibody (eBioJ105 (J105)), Brilliant Violet™ 711, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
CD279 (PD-1)
Concentration
5 μL/Test
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias
CD279, EGK_05005, hPD1, hPD-1, hPD-l, hSLE1, Ly101, mPD-1, PD1, PD-1, Pdc1, Pdcd1, programmed cell death 1, programmed cell death 1 protein, programmed cell death protein 1, programmed cell death protein 1-like, programmed death 1, Protein PD1, protein PD-1, sCD279, SLEB2, soluble CD279, systemic lupus erythematosus susceptibility 2
Gene Symbols
Pdcd1
Primary or Secondary
Primary
Content And Storage
4°, C, store in dark, DO NOT FREEZE!
Clone
eBioJ105 (J105)
Applications
Flow Cytometry
Conjugate
Brilliant Violet 711
Host Species
Mouse
Target Species
Human, Rhesus Monkey
Gene Accession No.
Q15116
Gene ID (Entrez)
100135775, 5133
Isotype
IgG1 κ
Purification Method
Affinity chromatography
Gene
Pdcd1
Related Products
Description
- Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC)
- T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC
- PD-1 can bind two different but related ligands, PDL-1 and PDL-2
- Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of "edanger signals"e such as LPS or other molecules associated with bacteria or other pathogens
- Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases
- Despite its predicted molecular weight, PD-1 often migrates at higher molecular weight in SDS-PAGE.
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Antigen: CD279 (PD-1)
Concentration: 5 μL/Test
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias: CD279, EGK_05005, hPD1, hPD-1, hPD-l, hSLE1, Ly101, mPD-1, PD1, PD-1, Pdc1, Pdcd1, programmed cell death 1, programmed cell death 1 protein, programmed cell death protein 1, programmed cell death protein 1-like, programmed death 1, Protein PD1, protein PD-1, sCD279, SLEB2, soluble CD279, systemic lupus erythematosus susceptibility 2
Gene Symbols: Pdcd1
Primary or Secondary: Primary
Content And Storage: 4°, C, store in dark, DO NOT FREEZE!
Clone: eBioJ105 (J105)
Applications: Flow Cytometry
Conjugate: Brilliant Violet 711
Host Species: Mouse
Target Species: Human, Rhesus Monkey
Gene Accession No.: Q15116
Gene ID (Entrez): 100135775, 5133
Isotype: IgG1 κ
Purification Method: Affinity chromatography
Gene: Pdcd1
Antigen:
CD279 (PD-1)
Concentration:
5 μL/Test
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
CD279, EGK_05005, hPD1, hPD-1, hPD-l, hSLE1, Ly101, mPD-1, PD1, PD-1, Pdc1, Pdcd1, programmed cell death 1, programmed cell death 1 protein, programmed cell death protein 1, programmed cell death protein 1-like, programmed death 1, Protein PD1, protein PD-1, sCD279, SLEB2, soluble CD279, systemic lupus erythematosus susceptibility 2
Gene Symbols:
Pdcd1
Primary or Secondary:
Primary
Content And Storage:
4°, C, store in dark, DO NOT FREEZE!
Clone:
eBioJ105 (J105)
Applications:
Flow Cytometry
Conjugate:
Brilliant Violet 711
Host Species:
Mouse
Target Species:
Human, Rhesus Monkey
Gene Accession No.:
Q15116
Gene ID (Entrez):
100135775, 5133
Isotype:
IgG1 κ
Purification Method:
Affinity chromatography
Gene:
Pdcd1
Antigen: MHC Class II (I-A/I-E)
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias: Abeta, AI323765, AI845868, cell surface glycoprotein, E-alpha-f, H-2 class II histocompatibility antigen, A beta chain, H-2 class II histocompatibility antigen, E-D alpha chain, H-2 class II histocompatibility antigen, E-K alpha chain, H-2 class II histocompatibility antigen, E-U alpha chain, H-2 class II histocompatibility antigen, I-E beta chain, H-2Ab, H2-Ab, H2-Ab1, H-2Ea, H2-Ea, H2-Ea-ps, H2Eb, H-2Eb, H2-Eb1, H2-iabeta, H2-IE-alpha, histocompatibility 2, class II antigen A, beta 1, histocompatibility 2, class II antigen E alpha, histocompatibility 2, class II antigen E alpha, pseudogene, histocompatibility 2, class II antigen E beta, Ia2, Ia-2, Ia3, Ia-3, Ia4, Ia-4, IAb, I-Ab, I-Abeta, I-Ad, I-Aq, I-E alpha MHC class II, I-E beta MHC class II, I-Ealpha, I-Ed, I-Ek, major histocompatibility complex class II beta chain, major histocompatibility complex H-2E beta chain, MHC class 2, MHC class II antigen A beta, MHC class II antigen E alpha, MHC class II H2-IA-beta-psi, MHC class II IE-b, MHC class II protein, MHC H2-IE-beta cell surface glycoprotein, response to metastatic cancers 1, Rmcs1
Gene Symbols: H2-Ab1, H2-Eb1
Primary or Secondary: Primary
Content And Storage: 4°, C, store in dark, DO NOT FREEZE!
Clone: M5/114.15.2
Applications: Flow Cytometry
Conjugate: Brilliant Violet 605
Host Species: Rat
Target Species: Mouse
Gene Accession No.: P01921, P04230, P06342, P06343, P06344, P06345, P06346, P14483
Gene ID (Entrez): 14961, 14969
Isotype: IgG2b κ
Purification Method: Affinity chromatography
Gene: H2-Ab1
Antigen:
MHC Class II (I-A/I-E)
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
Abeta, AI323765, AI845868, cell surface glycoprotein, E-alpha-f, H-2 class II histocompatibility antigen, A beta chain, H-2 class II histocompatibility antigen, E-D alpha chain, H-2 class II histocompatibility antigen, E-K alpha chain, H-2 class II histocompatibility antigen, E-U alpha chain, H-2 class II histocompatibility antigen, I-E beta chain, H-2Ab, H2-Ab, H2-Ab1, H-2Ea, H2-Ea, H2-Ea-ps, H2Eb, H-2Eb, H2-Eb1, H2-iabeta, H2-IE-alpha, histocompatibility 2, class II antigen A, beta 1, histocompatibility 2, class II antigen E alpha, histocompatibility 2, class II antigen E alpha, pseudogene, histocompatibility 2, class II antigen E beta, Ia2, Ia-2, Ia3, Ia-3, Ia4, Ia-4, IAb, I-Ab, I-Abeta, I-Ad, I-Aq, I-E alpha MHC class II, I-E beta MHC class II, I-Ealpha, I-Ed, I-Ek, major histocompatibility complex class II beta chain, major histocompatibility complex H-2E beta chain, MHC class 2, MHC class II antigen A beta, MHC class II antigen E alpha, MHC class II H2-IA-beta-psi, MHC class II IE-b, MHC class II protein, MHC H2-IE-beta cell surface glycoprotein, response to metastatic cancers 1, Rmcs1
Gene Symbols:
H2-Ab1, H2-Eb1
Primary or Secondary:
Primary
Content And Storage:
4°, C, store in dark, DO NOT FREEZE!
Clone:
M5/114.15.2
Applications:
Flow Cytometry
Conjugate:
Brilliant Violet 605
Host Species:
Rat
Target Species:
Mouse
Gene Accession No.:
P01921, P04230, P06342, P06343, P06344, P06345, P06346, P14483
Gene ID (Entrez):
14961, 14969
Isotype:
IgG2b κ
Purification Method:
Affinity chromatography
Gene:
H2-Ab1
Antigen: CD11c
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias: AI449405, CD11 antigen-like family member C, CD11c, CD11C (p150) alpha polypeptide, complement component 3 receptor 4 subunit, complement receptor 4, Cr4, integrin alpha X, integrin alpha-X, integrin aX, integrin subunit alpha X, integrin, alpha X, integrin, alpha X (antigen CD11C (p150), alpha polypeptide), integrin, alpha X (complement component 3 receptor 4 subunit), Itgax, Leu M5, leu M5, alpha subunit, leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150,95, leukocyte surface antigen p150,95, alpha subunit, myeloid membrane antigen, alpha subunit, N418, p150 95 integrin alpha chain, RGD1561123, SLEB6
Gene Symbols: Itgax
Primary or Secondary: Primary
Content And Storage: 4°, C, store in dark, DO NOT FREEZE!
Clone: N418
Applications: Flow Cytometry
Conjugate: Brilliant Ultraviolet 496
Host Species: Armenian Hamster
Target Species: Mouse
Gene Accession No.: Q9QXH4
Gene ID (Entrez): 16411
Isotype: IgG
Purification Method: Affinity chromatography
Gene: Itgax
Antigen:
CD11c
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
AI449405, CD11 antigen-like family member C, CD11c, CD11C (p150) alpha polypeptide, complement component 3 receptor 4 subunit, complement receptor 4, Cr4, integrin alpha X, integrin alpha-X, integrin aX, integrin subunit alpha X, integrin, alpha X, integrin, alpha X (antigen CD11C (p150), alpha polypeptide), integrin, alpha X (complement component 3 receptor 4 subunit), Itgax, Leu M5, leu M5, alpha subunit, leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150,95, leukocyte surface antigen p150,95, alpha subunit, myeloid membrane antigen, alpha subunit, N418, p150 95 integrin alpha chain, RGD1561123, SLEB6
Gene Symbols:
Itgax
Primary or Secondary:
Primary
Content And Storage:
4°, C, store in dark, DO NOT FREEZE!
Clone:
N418
Applications:
Flow Cytometry
Conjugate:
Brilliant Ultraviolet 496
Host Species:
Armenian Hamster
Target Species:
Mouse
Gene Accession No.:
Q9QXH4
Gene ID (Entrez):
16411
Isotype:
IgG
Purification Method:
Affinity chromatography
Gene:
Itgax
Antigen: CD11c
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias: AI449405, CD11 antigen-like family member C, CD11c, CD11C (p150) alpha polypeptide, complement component 3 receptor 4 subunit, complement receptor 4, Cr4, integrin alpha X, integrin alpha-X, integrin aX, integrin subunit alpha X, integrin, alpha X, integrin, alpha X (antigen CD11C (p150), alpha polypeptide), integrin, alpha X (complement component 3 receptor 4 subunit), Itgax, Leu M5, leu M5, alpha subunit, leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150,95, leukocyte surface antigen p150,95, alpha subunit, myeloid membrane antigen, alpha subunit, N418, p150 95 integrin alpha chain, RGD1561123, SLEB6
Gene Symbols: Itgax
Primary or Secondary: Primary
Content And Storage: 4°, C, store in dark, DO NOT FREEZE!
Clone: N418
Applications: Flow Cytometry
Conjugate: Brilliant Ultraviolet 496
Host Species: Armenian Hamster
Target Species: Mouse
Gene Accession No.: Q9QXH4
Gene ID (Entrez): 16411
Isotype: IgG
Purification Method: Affinity chromatography
Gene: Itgax
Antigen:
CD11c
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
AI449405, CD11 antigen-like family member C, CD11c, CD11C (p150) alpha polypeptide, complement component 3 receptor 4 subunit, complement receptor 4, Cr4, integrin alpha X, integrin alpha-X, integrin aX, integrin subunit alpha X, integrin, alpha X, integrin, alpha X (antigen CD11C (p150), alpha polypeptide), integrin, alpha X (complement component 3 receptor 4 subunit), Itgax, Leu M5, leu M5, alpha subunit, leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150,95, leukocyte surface antigen p150,95, alpha subunit, myeloid membrane antigen, alpha subunit, N418, p150 95 integrin alpha chain, RGD1561123, SLEB6
Gene Symbols:
Itgax
Primary or Secondary:
Primary
Content And Storage:
4°, C, store in dark, DO NOT FREEZE!
Clone:
N418
Applications:
Flow Cytometry
Conjugate:
Brilliant Ultraviolet 496
Host Species:
Armenian Hamster
Target Species:
Mouse
Gene Accession No.:
Q9QXH4
Gene ID (Entrez):
16411
Isotype:
IgG
Purification Method:
Affinity chromatography
Gene:
Itgax