200020326
Cyclophilin A Monoclonal Antibody (C1), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Cyclophilin A
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias
2700098C05, Cphn, CYCA, cyclophilin, Cyclophilin A, Cyclosporin A-binding protein, CyP A, CyP-18, CYPA, CyP-A, CYPH, EC 5.2.1.8, epididymis secretory sperm binding protein Li 69p, HEL-S-69p, HGNC:9253, I79_011869, MGC117158, MGC12404, MGC23397, p1B15, p31, Peptidyl-prolyl cis-trans isomerase A, Peptidyl-prolyl cis-trans isomerase A, N-terminally processed, peptidylprolyl isomerase A, peptidylprolyl isomerase A (cyclophilin A), PPIA, PPIase, PPIase A, rotamase, rotamase A, SP18, T cell cyclophilin
Gene Symbols
Ppia
Isotype
IgG2a κ
Purification Method
Protein A/G
Gene
Ppia
Clone
C1
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human, Mouse, Porcine, Rat
Gene Accession No.
P10111, P17742, P62936, P62937
Gene ID (Entrez)
25518, 268373, 397637, 5478
Immunogen
Recombinant Mouse CYPA protein, Val2-Leu164 (Accession #P17742)
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Related Products
Description
- Immunophilins are a family of soluble cytosolic receptors capable of binding to one of two major immunosuppressant agents - cyclosporin A (CsA) or FK506
- Proteins that bind FK506 are termed FK506 Binding Proteins (FKBPs) and those that bind cyclosporin A are called cyclophilins (CyP)
- Both CyP:CsA and FKBP:FK506 complexes have been shown to inhibit calcineurin, a calcium and calmodulin dependent protein phosphatase which has been implicated as an important signaling enzyme in T-cell activation, providing a possible mechanism of immunosuppression by CsA and FK506
- Immunophilins function as peptidyl prolyl cis-trans-isomerases (PPIase) whose activity is inhibited by their respective immunosuppressant compounds
- As PPIase's, immunophilins accelerate folding of some proteins both in vivo and in vitro by catalyzing slow steps in the initial folding and rearrangement of proline containing proteins
- Within the cyclophilin family, there are several different proteins which show a high degree of homology including CyPA, CyPB and CyPC
- CyPA, also termed CyP-18, is the most abundant and ubiquitous cyclophilin found in all vertebrate tissues and is present in T-cells.
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Antigen: Cyclophilin A
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias: 2700098C05, Cphn, CYCA, cyclophilin, Cyclophilin A, Cyclosporin A-binding protein, CyP A, CyP-18, CYPA, CyP-A, CYPH, EC 5.2.1.8, epididymis secretory sperm binding protein Li 69p, HEL-S-69p, HGNC:9253, I79_011869, MGC117158, MGC12404, MGC23397, p1B15, p31, Peptidyl-prolyl cis-trans isomerase A, Peptidyl-prolyl cis-trans isomerase A, N-terminally processed, peptidylprolyl isomerase A, peptidylprolyl isomerase A (cyclophilin A), PPIA, PPIase, PPIase A, rotamase, rotamase A, SP18, T cell cyclophilin
Gene Symbols: Ppia
Isotype: IgG2a κ
Purification Method: Protein A/G
Gene: Ppia
Clone: C1
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human, Mouse, Porcine, Rat
Gene Accession No.: P10111, P17742, P62936, P62937
Gene ID (Entrez): 25518, 268373, 397637, 5478
Immunogen: Recombinant Mouse CYPA protein, Val2-Leu164 (Accession #P17742)
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen:
Cyclophilin A
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias:
2700098C05, Cphn, CYCA, cyclophilin, Cyclophilin A, Cyclosporin A-binding protein, CyP A, CyP-18, CYPA, CyP-A, CYPH, EC 5.2.1.8, epididymis secretory sperm binding protein Li 69p, HEL-S-69p, HGNC:9253, I79_011869, MGC117158, MGC12404, MGC23397, p1B15, p31, Peptidyl-prolyl cis-trans isomerase A, Peptidyl-prolyl cis-trans isomerase A, N-terminally processed, peptidylprolyl isomerase A, peptidylprolyl isomerase A (cyclophilin A), PPIA, PPIase, PPIase A, rotamase, rotamase A, SP18, T cell cyclophilin
Gene Symbols:
Ppia
Isotype:
IgG2a κ
Purification Method:
Protein A/G
Gene:
Ppia
Clone:
C1
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human, Mouse, Porcine, Rat
Gene Accession No.:
P10111, P17742, P62936, P62937
Gene ID (Entrez):
25518, 268373, 397637, 5478
Immunogen:
Recombinant Mouse CYPA protein, Val2-Leu164 (Accession #P17742)
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen: RBP5
Concentration: 0.5 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias: cellular retinol binding protein 5, cellular retinol-binding protein III, CRBP3, CRBPIII, CRBP-III, HRBPiso, putative cellular retinol-binding protein CRBP III, RBP5, retinol binding protein 5, retinol binding protein 5, cellular, retinol-binding protein 5, retinol-binding protein 5, cellular
Gene Symbols: RBP5
Isotype: IgG
Purification Method: Protein A
Gene: RBP5
Clone: __
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Bovine, Porcine
Gene Accession No.: P82708
Gene ID (Entrez): 100270724, 539418
Immunogen: Recombinant Bovine RBP5 protein, Met1-Lys135 (Accession #P82708)
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen:
RBP5
Concentration:
0.5 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias:
cellular retinol binding protein 5, cellular retinol-binding protein III, CRBP3, CRBPIII, CRBP-III, HRBPiso, putative cellular retinol-binding protein CRBP III, RBP5, retinol binding protein 5, retinol binding protein 5, cellular, retinol-binding protein 5, retinol-binding protein 5, cellular
Gene Symbols:
RBP5
Isotype:
IgG
Purification Method:
Protein A
Gene:
RBP5
Clone:
__
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Bovine, Porcine
Gene Accession No.:
P82708
Gene ID (Entrez):
100270724, 539418
Immunogen:
Recombinant Bovine RBP5 protein, Met1-Lys135 (Accession #P82708)
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen: RBP5
Concentration: 0.5 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias: cellular retinol binding protein 5, cellular retinol-binding protein III, CRBP3, CRBPIII, CRBP-III, HRBPiso, putative cellular retinol-binding protein CRBP III, RBP5, retinol binding protein 5, retinol binding protein 5, cellular, retinol-binding protein 5, retinol-binding protein 5, cellular
Gene Symbols: RBP5
Isotype: IgG
Purification Method: Protein A
Gene: RBP5
Clone: __
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Bovine, Porcine
Gene Accession No.: P82708
Gene ID (Entrez): 100270724, 539418
Immunogen: Recombinant Bovine RBP5 protein, Met1-Lys135 (Accession #P82708)
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen:
RBP5
Concentration:
0.5 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias:
cellular retinol binding protein 5, cellular retinol-binding protein III, CRBP3, CRBPIII, CRBP-III, HRBPiso, putative cellular retinol-binding protein CRBP III, RBP5, retinol binding protein 5, retinol binding protein 5, cellular, retinol-binding protein 5, retinol-binding protein 5, cellular
Gene Symbols:
RBP5
Isotype:
IgG
Purification Method:
Protein A
Gene:
RBP5
Clone:
__
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Bovine, Porcine
Gene Accession No.:
P82708
Gene ID (Entrez):
100270724, 539418
Immunogen:
Recombinant Bovine RBP5 protein, Met1-Lys135 (Accession #P82708)
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen: MPZ
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias: Charcot-Marie-Tooth neuropathy 1B, CHM, CMT1, CMT1B, CMT2I, CMT2J, CMT4E, CMTDI3, CMTDID, DSS, HMSNIB, MPP, MPZ, Myelin peripheral protein, myelin protein P0, Myelin protein zero, myelin protein zero (Charcot-Marie-Tooth neuropathy 1B), P0, P-zero
Gene Symbols: MPZ
Isotype: IgG3 κ
Purification Method: Protein A/G
Gene: MPZ
Clone: C13
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human, Mouse, Porcine, Rat
Gene Accession No.: P06907, P25189, P27573
Gene ID (Entrez): 100153273, 17528, 24564, 4359
Immunogen: Recombinant Human MPZ protein, Ile30-Lys248 (Accession #P25189)
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen:
MPZ
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias:
Charcot-Marie-Tooth neuropathy 1B, CHM, CMT1, CMT1B, CMT2I, CMT2J, CMT4E, CMTDI3, CMTDID, DSS, HMSNIB, MPP, MPZ, Myelin peripheral protein, myelin protein P0, Myelin protein zero, myelin protein zero (Charcot-Marie-Tooth neuropathy 1B), P0, P-zero
Gene Symbols:
MPZ
Isotype:
IgG3 κ
Purification Method:
Protein A/G
Gene:
MPZ
Clone:
C13
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human, Mouse, Porcine, Rat
Gene Accession No.:
P06907, P25189, P27573
Gene ID (Entrez):
100153273, 17528, 24564, 4359
Immunogen:
Recombinant Human MPZ protein, Ile30-Lys248 (Accession #P25189)
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.