200020353

Arginase 1 Monoclonal Antibody (C7), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Arginase 1

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

AI, A-I, AI type I arginase, AI256583, Arg1, Arg-1, Arginase, arginase 1, arginase 1 liver, arginase 1, liver, arginase I, arginase, liver, Arginase1, arginase-1, HGNC:663, Liver Arginase, Liver-type arginase, PGIF, similar to arginase, type I, Type 1 Arginase, type I arginase

Gene Symbols

ARG1

Isotype

IgG1 κ

Purification Method

Protein A/G

Gene

ARG1

Clone

C7

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human, Porcine

Gene Accession No.

P05089, Q95JC8

Gene ID (Entrez)

383, 397115

Immunogen

Recombinant Human ARG protein, Met1-Lys322 (Accession #P05089)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Description

  • Arginase-1 (Arg1) is a 35 kDa enzyme converting L-arginine to urea and L-ornithine, which is the final step in the urea cycle
  • The resulting polyamines are important for cell proliferation and removal of toxins that arise from protein degradation
  • By degrading arginine, Arginase 1 deprives NO synthase of its substrate and down-regulates nitric oxide production
  • In both human and mouse, Arginase 1 is expressed in the liver, neutrophils, myeloid derived suppressor cells (MDSC) and neural stem cells
  • In human, expression in blood neutrophils but not in CCR3+ granulocytes has been reported
  • In mice, expression of Arginase 1 is one of the hallmarks of alternatively activated macrophages (M2a)
  • Arginase-1 may be expressed in the myeloid cells infiltrating tumors, and is typically found in the majority of hepatocellular carcinomas
  • Defects in Arginase 1 are the cause of argininemia, an autosomal recessive disorder characterized by hyperammonemia.

Compare Similar Items

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Img

Fischer Scientific

200020353

Mouse Monoclonal Antibody...


Antigen:
Arginase 1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
AI, A-I, AI type I arginase, AI256583, Arg1, Arg-1, Arginase, arginase 1, arginase 1 liver, arginase 1, liver, arginase I, arginase, liver, Arginase1, arginase-1, HGNC:663, Liver Arginase, Liver-type arginase, PGIF, similar to arginase, type I, Type 1 Arginase, type I arginase

Gene Symbols:
ARG1

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
ARG1

Clone:
C7

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Porcine

Gene Accession No.:
P05089, Q95JC8

Gene ID (Entrez):
383, 397115

Immunogen:
Recombinant Human ARG protein, Met1-Lys322 (Accession #P05089)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Img

Fischer Scientific

200020354

Rabbit Polyclonal Antibody...


Antigen:
Galectin 12

Concentration:
0.5 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
AW987437, GAL12, gal-12, galectin 12, galectin-12, Galectin-related inhibitor of proliferation, galectin-related inhibitor of proliferation 1, GRIP1, lectin, galactose binding, soluble 12, lectin, galactoside binding soluble 12, lectin, galactoside-binding, soluble, 12, LGALS12, testicular secretory protein Li 26

Gene Symbols:
LGALS12

Isotype:
IgG

Purification Method:
Protein A

Gene:
LGALS12

Clone:
__

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Porcine

Gene Accession No.:
__

Gene ID (Entrez):
100217395

Immunogen:
Recombinant Pig GAL12 protein, Met1-Tyr314 (Accession #B7U2G9)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Img

Fischer Scientific

200020354

Rabbit Polyclonal Antibody...


Antigen:
Galectin 12

Concentration:
0.5 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
AW987437, GAL12, gal-12, galectin 12, galectin-12, Galectin-related inhibitor of proliferation, galectin-related inhibitor of proliferation 1, GRIP1, lectin, galactose binding, soluble 12, lectin, galactoside binding soluble 12, lectin, galactoside-binding, soluble, 12, LGALS12, testicular secretory protein Li 26

Gene Symbols:
LGALS12

Isotype:
IgG

Purification Method:
Protein A

Gene:
LGALS12

Clone:
__

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Porcine

Gene Accession No.:
__

Gene ID (Entrez):
100217395

Immunogen:
Recombinant Pig GAL12 protein, Met1-Tyr314 (Accession #B7U2G9)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Img

Fischer Scientific

200020358

Rabbit Polyclonal Antibody...


Antigen:
RBP2

Concentration:
0.5 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
AA409370, C76986, Cellular retinol-binding protein II, CRABP-II, CRBP2, Crbp-2, CrbpII, CRBP-II, Histone demethylase JARID1A, Jarid1a, jumonji, AT rich interactive domain 1A (Rbp2 like), Jumonji, AT rich interactive domain 1A (RBP2-like), jumonji/ARID domain-containing protein 1A, KDM5A, lysine (K)-specific demethylase 5A, lysine demethylase 5A, lysine-specific demethylase 5A, RBBP2, RBBP-2, RBP2, Rbp-2, RBPC2, retinoblastoma binding protein 2, retinoblastoma-binding protein 2, retinol binding protein 2, retinol binding protein 2, cellular, retinol-binding protein 2, Retinol-binding protein 2 cellular, retinol-binding protein 2, cellular

Gene Symbols:
RBP2

Isotype:
IgG

Purification Method:
Protein A

Gene:
RBP2

Clone:
__

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse, Porcine, Rat

Gene Accession No.:
P06768, P50120, P50121, Q08652

Gene ID (Entrez):
19660, 24710, 407611, 5948

Immunogen:
Recombinant Human RBP2 protein, Met1-Lys134 (Accession #P50120)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.