FEMA550871

Arginase 1 Monoclonal Antibody (C7), Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550871-Each-of-1 In Stock ₹ 34,908.48

FEMA550871 - Each of 1

₹ 34,908.48

In Stock

Quantity

1

Base Price: ₹ 34,908.48

GST (18%): ₹ 6,283.526

Total Price: ₹ 41,192.006

Antigen

Arginase 1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.

P05089, Q95JC8

Gene Symbols

ARG1

Immunogen

Recombinant Human ARG protein, Met1-Lys322 (Accession #P05089)

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human, Porcine

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

C7

Conjugate

Unconjugated

Gene

ARG1

Gene Alias

AI, A-I, AI type I arginase, AI256583, Arg1, Arg-1, Arginase, arginase 1, arginase 1 liver, arginase 1, liver, arginase I, arginase, liver, Arginase1, arginase-1, HGNC:663, Liver Arginase, Liver-type arginase, PGIF, similar to arginase, type I, Type 1 Arginase, type I arginase

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

383, 397115

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1 κ

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Description

  • Arginase-1 (Arg1) is a 35 kDa enzyme converting L-arginine to urea and L-ornithine, which is the final step in the urea cycle
  • The resulting polyamines are important for cell proliferation and removal of toxins that arise from protein degradation
  • By degrading arginine, Arginase 1 deprives NO synthase of its substrate and down-regulates nitric oxide production
  • In both human and mouse, Arginase 1 is expressed in the liver, neutrophils, myeloid derived suppressor cells (MDSC) and neural stem cells
  • In human, expression in blood neutrophils but not in CCR3+ granulocytes has been reported
  • In mice, expression of Arginase 1 is one of the hallmarks of alternatively activated macrophages (M2a)
  • Arginase-1 may be expressed in the myeloid cells infiltrating tumors, and is typically found in the majority of hepatocellular carcinomas
  • Defects in Arginase 1 are the cause of argininemia, an autosomal recessive disorder characterized by hyperammonemia.

Compare Similar Items

Show Difference

Img

Fischer Scientific

FEMA550871

--


Antigen:
Arginase 1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
P05089, Q95JC8

Gene Symbols:
ARG1

Immunogen:
Recombinant Human ARG protein, Met1-Lys322 (Accession #P05089)

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Porcine

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C7

Conjugate:
Unconjugated

Gene:
ARG1

Gene Alias:
AI, A-I, AI type I arginase, AI256583, Arg1, Arg-1, Arginase, arginase 1, arginase 1 liver, arginase 1, liver, arginase I, arginase, liver, Arginase1, arginase-1, HGNC:663, Liver Arginase, Liver-type arginase, PGIF, similar to arginase, type I, Type 1 Arginase, type I arginase

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
383, 397115

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

Img

Fischer Scientific

FEMA550872

--


Antigen:
Arginase 1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
P05089, Q95JC8

Gene Symbols:
ARG1

Immunogen:
Recombinant Human ARG protein, Met1-Lys322 (Accession #P05089)

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Porcine

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C7

Conjugate:
Unconjugated

Gene:
ARG1

Gene Alias:
AI, A-I, AI type I arginase, AI256583, Arg1, Arg-1, Arginase, arginase 1, arginase 1 liver, arginase 1, liver, arginase I, arginase, liver, Arginase1, arginase-1, HGNC:663, Liver Arginase, Liver-type arginase, PGIF, similar to arginase, type I, Type 1 Arginase, type I arginase

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
383, 397115

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

Img

Fischer Scientific

FEMA550873

--


Antigen:
IDO

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
P14902

Gene Symbols:
Ido1

Immunogen:
Recombinant Human IDO protein, Ala2-Gly403 (Accession #P14902)

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Porcine

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C14

Conjugate:
Unconjugated

Gene:
Ido1

Gene Alias:
EC 1.13.11.52, IDO, IDO1, IDO-1, INDO, indolamine 2,3 dioxygenase, indole 2,3-dioxygenase, indoleamine, indoleamine 2,3-dioxygenase 1, indoleamine 23-dioxygenase, Indoleamine-2, indoleamine-pyrrole 2,3 dioxygenase, indoleamine-pyrrole 2,3-dioxygenase

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
100519877, 3620

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2a κ

Img

Fischer Scientific

FEMA550874

--


Antigen:
IDO

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Accession No.:
P14902

Gene Symbols:
Ido1

Immunogen:
Recombinant Human IDO protein, Ala2-Gly403 (Accession #P14902)

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Porcine

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C14

Conjugate:
Unconjugated

Gene:
Ido1

Gene Alias:
EC 1.13.11.52, IDO, IDO1, IDO-1, INDO, indolamine 2,3 dioxygenase, indole 2,3-dioxygenase, indoleamine, indoleamine 2,3-dioxygenase 1, indoleamine 23-dioxygenase, Indoleamine-2, indoleamine-pyrrole 2,3 dioxygenase, indoleamine-pyrrole 2,3-dioxygenase

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
100519877, 3620

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2a κ