200020373

CTLA-4 Monoclonal Antibody (D13), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

CTLA-4

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

ALPS5, CD, CD152, CD152 antigen, CD152 isoform, CD152 protein, CD152 protein precursor, celiac disease 3, CELIAC3, Ctla4, CTLA-4, cytotoxic T lymphocyte associated antigen 4 short spliced form, cytotoxic T-lymphocyte associated protein 4, cytotoxic T-lymphocyte protein 4, cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM, cytotoxic T-lymphocyte-associated antigen 4, cytotoxic T-lymphocyte-associated protein 4, cytotoxic T-lymphocyte-associated serine esterase-4, EGK_04712, GRD4, GSE, ICOS, IDDM12, insulin-dependent diabetes mellitus 12, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4, Ly-56, sCTLA4, soluble form, transmembrane form

Gene Symbols

CTLA4

Isotype

IgG1 κ

Purification Method

Protein A/G

Gene

CTLA4

Clone

D13

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human, Porcine

Gene Accession No.

P16410, Q9MYX7

Gene ID (Entrez)

1493, 397286

Immunogen

Recombinant Human CTLA4 protein, Gly52-Cys211 (Accession #P16410)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Description

  • CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells
  • It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28
  • However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning
  • Intracellular CTLA4 is also found in regulatory T cells and may be important to their function.

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Show Difference

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Fischer Scientific

200020373

Mouse Monoclonal Antibody...


Antigen:
CTLA-4

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
ALPS5, CD, CD152, CD152 antigen, CD152 isoform, CD152 protein, CD152 protein precursor, celiac disease 3, CELIAC3, Ctla4, CTLA-4, cytotoxic T lymphocyte associated antigen 4 short spliced form, cytotoxic T-lymphocyte associated protein 4, cytotoxic T-lymphocyte protein 4, cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM, cytotoxic T-lymphocyte-associated antigen 4, cytotoxic T-lymphocyte-associated protein 4, cytotoxic T-lymphocyte-associated serine esterase-4, EGK_04712, GRD4, GSE, ICOS, IDDM12, insulin-dependent diabetes mellitus 12, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4, Ly-56, sCTLA4, soluble form, transmembrane form

Gene Symbols:
CTLA4

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
CTLA4

Clone:
D13

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Porcine

Gene Accession No.:
P16410, Q9MYX7

Gene ID (Entrez):
1493, 397286

Immunogen:
Recombinant Human CTLA4 protein, Gly52-Cys211 (Accession #P16410)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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200020376

Rabbit Polyclonal Antibody...


Antigen:
VCAM-1

Concentration:
0.5 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
adhesion molecule VCAM-1, CD106, CD106 antigen, DKFZp779G2333, INCAM100, INCAM-100, MGC99561, sCD106, soluble CD106, soluble VCAM 1, sVCAM 1, vascular cell adhesion molecule, vascular cell adhesion molecule 1, vascular cell adhesion molecule-1, vascular cell adhesion protein 1, V-CAM 1, Vcam1, Vcam-1, VCAM1B

Gene Symbols:
VCAM1

Isotype:
IgG

Purification Method:
Protein A

Gene:
VCAM1

Clone:
__

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Rabbit

Gene Accession No.:
P19320

Gene ID (Entrez):
100008901, 7412

Immunogen:
Recombinant Rabbit VCAM1 protein, Ile409-Thr682 (Accession #Q865F2)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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200020379

Mouse Monoclonal Antibody...


Antigen:
ALOX5

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
5 - Lipoxygenase, 5-lipoxygenase, 5LO, 5-LO, 5-LOX, 5LPG, 5LX, AI850497, ALOX5, Arachidonate 5-lipoxygenase, arachidonic 5-lipoxygenase alpha-10 isoform, arachidonic 5-lipoxygenase delta-10-13 isoform, arachidonic 5-lipoxygenase delta-13 isoform, arachidonic 5-lipoxygenase delta-p10 isoform, arachidonic acid 5-lipoxygenase, F730011J02, leukotriene A4 synthase, LOG5, LOW QUALITY PROTEIN: arachidonate 5-lipoxygenase, lox5, LOX-5, LOX5A, polyunsaturated fatty acid 5-lipoxygenase, RP11-67C2.3

Gene Symbols:
ALOX5

Isotype:
IgG2b κ

Purification Method:
Protein A/G

Gene:
ALOX5

Clone:
D2

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Rat

Gene Accession No.:
P09917, P12527

Gene ID (Entrez):
240, 25290

Immunogen:
Recombinant Human 5-LO protein, Glu461-Ser671 (Accession #P09917)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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200020380

Rabbit Polyclonal Antibody...


Antigen:
S100B

Concentration:
0.5 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
AI850290, Bpb, hypothetical protein LOC525716, NEF, protein S100-B, S100, S100 calcium binding protein B, S100 calcium binding protein beta (neural), S100 calcium-binding protein B, S100 calcium-binding protein beta (neural), S-100 calcium-binding protein beta subunit, S100 calcium-binding protein, beta (neural), S-100 calcium-binding protein, beta chain, S100 protein beta chain, S-100 protein beta chain, S-100 protein subunit beta, S100 protein, beta polypeptide, S100 protein, beta polypeptide, neural, S100B, S100-B, S100beta, S100P

Gene Symbols:
S100B

Isotype:
IgG

Purification Method:
Protein A

Gene:
S100B

Clone:
__

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse, Porcine, Rat

Gene Accession No.:
P04271, P04631, P50114

Gene ID (Entrez):
100623510, 20203, 25742, 6285

Immunogen:
Recombinant Human S100B protein, Met1-Glu92 (Accession #P04271)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.