200020434

TNF alpha Monoclonal Antibody (MP6-XT22), Brilliant Violet™ 786, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

TNF alpha

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias

APC1 protein, Cachectin, C-domain 1, C-domain 2, cTNF, DADB-70P7.1, DIF, ICD1, ICD2, Intracellular domain 1, Intracellular domain 2, N-terminal fragment, NTF, RATTNF, Tnf, TNF alpha, TNF superfamily, TNF a, TNF, macrophage-derived, TNF, monocyte-derived, TNFA, TNF-a, TNFalpha, TNF-alpha, Tnfsf1a, TNFSF2, TNFa, TNLG1F, Tumor necrosis factor, tumor necrosis factor (TNF superfamily, member 2), tumor necrosis factor alpha, tumor necrosis factor alpha (cachetin), tumor necrosis factor alpha precursor, tumor necrosis factor ligand 1F, tumor necrosis factor ligand superfamily member 2, Tumor necrosis factor, membrane form, Tumor necrosis factor, soluble form, tumor necrosis factor-alpha, tumor necrosis factor-alpha precursor, tumor-necrosis factor, tumour necrosis factor

Gene Symbols

Tnf

Primary or Secondary

Primary

Content And Storage

4°, C, store in dark, DO NOT FREEZE!

Clone

MP6-XT22

Applications

Flow Cytometry

Conjugate

Brilliant Violet 786

Host Species

Rat

Target Species

Mouse

Gene Accession No.

P06804

Gene ID (Entrez)

21926

Isotype

IgG1 κ

Purification Method

Affinity chromatography

Gene

Tnf

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Description

  • TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily
  • This cytokine is mainly secreted by macrophage and bind to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR
  • TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation
  • TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions
  • Knockout studies in mice also suggested the neuroprotective function of TNF alpha, and has been observed to causes tumor necrosis when injected into tumor-bearing mice
  • Other functions of TNF-alpha include its role in the immune response to bacterial, viral, parasitic and certain fungal infections, as well as its role in the necrosis of specific tumors
  • TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon-gamma in its cytotoxicity
  • This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.

Compare Similar Items

Show Difference

Img

Fischer Scientific

200020434

Rat Monoclonal Antibody...


Antigen:
TNF alpha

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias:
APC1 protein, Cachectin, C-domain 1, C-domain 2, cTNF, DADB-70P7.1, DIF, ICD1, ICD2, Intracellular domain 1, Intracellular domain 2, N-terminal fragment, NTF, RATTNF, Tnf, TNF alpha, TNF superfamily, TNF a, TNF, macrophage-derived, TNF, monocyte-derived, TNFA, TNF-a, TNFalpha, TNF-alpha, Tnfsf1a, TNFSF2, TNFa, TNLG1F, Tumor necrosis factor, tumor necrosis factor (TNF superfamily, member 2), tumor necrosis factor alpha, tumor necrosis factor alpha (cachetin), tumor necrosis factor alpha precursor, tumor necrosis factor ligand 1F, tumor necrosis factor ligand superfamily member 2, Tumor necrosis factor, membrane form, Tumor necrosis factor, soluble form, tumor necrosis factor-alpha, tumor necrosis factor-alpha precursor, tumor-necrosis factor, tumour necrosis factor

Gene Symbols:
Tnf

Primary or Secondary:
Primary

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Clone:
MP6-XT22

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 786

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P06804

Gene ID (Entrez):
21926

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Gene:
Tnf

Img

Fischer Scientific

200020435

Mouse Monoclonal Antibody...


Antigen:
CD22

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
A530093D23, B-cell receptor CD22, BL-CAM, B-lymphocyte cell adhesion molecule, B-lymphocyte cell adhesion molecule (BL-CAM), Cd22, CD22 antigen, CD22 molecule, FLJ22814, Lectin 2, Leu-14, Lyb8, Lyb-8, MGC130020, sialic acid binding Ig-like lectin 2, sialic acid-binding Ig-like lectin 2, Sialic acid-binding Ig-like lectin 2 (Siglec-2), Siglec2, Siglec-2, T-cell surface antigen Leu-14

Gene Symbols:
CD22

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Clone:
C2

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P20273

Gene ID (Entrez):
933

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
CD22

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Fischer Scientific

200020436

Mouse Monoclonal Antibody...


Antigen:
Cytokeratin 20

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
9030623C06Rik, CD20, CK20, CK-20, CK-21, cytokeratin 20, cytokeratin 21, cytokeratin-20, Cytokeratin-21, K20, keratin 20, keratin 20, type I, keratin, type I cytoskeletal 20, Keratin-20, krt20, Krt21, MGC35423, Protein IT

Gene Symbols:
KRT20

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Clone:
C2

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Porcine

Gene Accession No.:
P35900, Q29218

Gene ID (Entrez):
100520330, 54474

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
KRT20

Img

Fischer Scientific

200020436

Mouse Monoclonal Antibody...


Antigen:
Cytokeratin 20

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
9030623C06Rik, CD20, CK20, CK-20, CK-21, cytokeratin 20, cytokeratin 21, cytokeratin-20, Cytokeratin-21, K20, keratin 20, keratin 20, type I, keratin, type I cytoskeletal 20, Keratin-20, krt20, Krt21, MGC35423, Protein IT

Gene Symbols:
KRT20

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Clone:
C2

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Porcine

Gene Accession No.:
P35900, Q29218

Gene ID (Entrez):
100520330, 54474

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Gene:
KRT20