200020440

Vinculin Monoclonal Antibody (C4), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Vinculin

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

9430097D22, AA571387, AI462105, AW545629, CMD1W, CMH15, epididymis luminal protein 114, HEL114, metavinculin, meta-vinculin, metavinculin {ECO:0000250, MV, MVCL, RP11-178G16.3, UniProtKB:P18206}, unnamed protein product, Vcl, vcl {ECO:0000250, VIN, vinc, vinc 1, VINC1, Vinculin, vinculin {ECO:0000250

Gene Symbols

VCL

Isotype

IgG2b κ

Purification Method

Protein A/G

Gene

VCL

Clone

C4

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Bovine, Canine, Chicken, Guinea Pig, Human

Gene Accession No.

P12003, P18206, P26234, P85972, Q64727

Gene ID (Entrez)

100357160, 100722183, 22330, 305679, 396422, 396974, 479252, 7414, 783645

Immunogen

Recombinant Human/Mouse/Rat VCL protein, Lys1020-Gln1134 (Accession #P18206)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Description

  • Vinculin (VCL) is a cytoskeletal protein associated with cell-cell and cell-extracellular matrix adherens-type junctions
  • It functions as one of several interacting proteins involved in anchoring F-actin to the membrane
  • It has been shown that a sequence of molecular interactions might be involved in the transmembrane assembly of adhesion plaques
  • In the assembly of adhesion plaques, the beta subunit of integrin binds to talin
  • Talin binds to vinculin that interacts with alpha-actinin and possibly with itself
  • Since alpha-actinin binds to and cross-links actin filaments, vinculin represents a key element in the transmembrane linkage of the extracellular matrix to the cytoplasmic microfilament system
  • Mutations in the gene can result in cardiomyopathy dilated 1W or familial hypertrophic 15.

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Img

Fischer Scientific

200020440

Mouse Monoclonal Antibody...


Antigen:
Vinculin

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
9430097D22, AA571387, AI462105, AW545629, CMD1W, CMH15, epididymis luminal protein 114, HEL114, metavinculin, meta-vinculin, metavinculin {ECO:0000250, MV, MVCL, RP11-178G16.3, UniProtKB:P18206}, unnamed protein product, Vcl, vcl {ECO:0000250, VIN, vinc, vinc 1, VINC1, Vinculin, vinculin {ECO:0000250

Gene Symbols:
VCL

Isotype:
IgG2b κ

Purification Method:
Protein A/G

Gene:
VCL

Clone:
C4

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Bovine, Canine, Chicken, Guinea Pig, Human

Gene Accession No.:
P12003, P18206, P26234, P85972, Q64727

Gene ID (Entrez):
100357160, 100722183, 22330, 305679, 396422, 396974, 479252, 7414, 783645

Immunogen:
Recombinant Human/Mouse/Rat VCL protein, Lys1020-Gln1134 (Accession #P18206)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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200020441

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Antigen:
beta Tubulin

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias:
2310057H16Rik, 2810484G07Rik, 3200002H15Rik, AA408537, AI325297, AI596182, B130022C14Rik, bA631M21.2, BB220206, beta 5-tubulin, beta Ib tubulin, beta tubulin, beta tubulin 1, beta-4, beta-4 tubulin, beta-4-tubulin, beta-5, beta-5 tubulin, beta5-tubulin, betaIII-tubulin, beta-tubulin, beta-tubulin class-III, Beta-tubulin class-V, beta-tubulin class-VI, Beta-tubulin isotype I, c(beta)7 tubulin, CDCBM, CDCBM1, CDCBM5, CDCBM6, CFEOM3, CFEOM3A, class I beta tubulin, Class I beta-tubulin, class IIa beta-tubulin, class III beta-tubulin, class IVa beta-tubulin, class V beta tubulin, class V beta-tubulin, CSCSC1, dJ40E16.7, dystonia 4, torsion (autosomal dominant), DYT4, FEOM3, HSA10p15 beta-tubulin 4Q, HsT1601, hypothetical protein LOC540236, hypothetical protein LOC550458, I79_000194, I79_012097, LOC100349792, LOC100761889, LOW QUALITY PROTEIN: tubulin beta-6 chain, M(beta)1, M(beta)2, M(beta)3, M(beta)4, M(beta)5, M(beta)6, M40, M40 antibody, MGC128415 protein, MGC137802 protein, neuron-specific class III beta-tubulin, OK/SW-cl.56, OOMD, OOMD2, RGD1305887, si:ch211-122i22.4, si:ch211-9a18.2, Tubb, tubb beta-5, tubb.L, Tubb1, TUBB2, Tubb2a, tubb2a {ECO:0000250, Tubb3, TUBB4, TUBB4A, tubb5, TUBB-5, TUBB6, TUBB8, Tubulin 5 beta, tubulin beta, tubulin beta 1 class VI, tubulin beta 2A class IIa, tubulin beta 3 class III, tubulin beta 4', tubulin beta 4A class IVa, tubulin beta 6 class V, tubulin beta 8 class VIII, Tubulin beta chain, tubulin beta class I, tubulin beta class I L homeolog, Tubulin beta class IIa, Tubulin beta class V, tubulin beta MGC4083, tubulin beta-1, tubulin beta-1 chain, tubulin beta-1 chain-like, tubulin beta-2A chain, tubulin beta-2B chain, tubulin beta-3 chain, Tubulin beta-4 chain, tubulin beta-4A chain, Tubulin beta-5 chain, tubulin beta-5 chain, tubulin beta-6 chain, tubulin beta-6 chain, Tubulin beta-7 chain, tubulin beta-8 chain, Tubulin beta-III, tubulin, beta 1 class VI, tubulin, beta 2, tubulin, beta 2A, tubulin, beta 2A class IIA, tubulin, beta 3, tubulin, beta 3 class III, tubulin, beta 4, tubulin, beta 4 class IVa, tubulin, beta 4A class IVa, tubulin, beta 5, tubulin, beta 5 class I, tubulin, beta 6 class V, tubulin, beta class I, tubulin, beta family 1, tubulin, beta polypeptide, tubulin, beta polypeptide 2, tubulin, beta, 3, tubulin, beta, 4, tubulin, beta, 5, uncharacterized protein LOC550458, UniProtKB:Q7TMM9}, Unknown (protein for MGC:134115), unnamed protein product, XELAEV_18039222mg, XLOT, zbetaI, zgc:112515

Gene Symbols:
TUBB, Tubb1, Tubb2a, Tubb3, Tubb4a, Tubb5, Tubb6, TUBB8

Isotype:
IgG2b κ

Purification Method:
Protein A/G

Gene:
Tubb3

Clone:
C3

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Bovine, Canine, Chicken, Goat, Guinea Pig

Gene Accession No.:
P04350, P07437, P09207, P09244, P09652, P09653, Q13509, Q13885, Q2HJ81, Q2KJD0, Q2T9S0, Q3ZBU7, Q3ZCM7, Q9BUF5, Q9H4B7

Gene ID (Entrez):
100295973, 100303606, 100713236, 100718713, 100720651, 100731652, 100732882, 100733481, 100855815, 101106224, 101115144, 102154194, 102168953, 102178062, 102178409, 102188330, 10381, 10382, 105609865, 108633269, 203068, 347688, 386701, 396254, 396427, 421037, 431043, 474830, 480213, 485950, 534206, 540236, 541271, 550458, 558552, 615087, 7280, 768070, 768337, 81027, 84617

Immunogen:
Recombinant Human TUBb protein, Val170-Val419 (Accession #P07437)

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Img

Fischer Scientific

200020443

Achieve outstanding temperature uni...


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Img

Fischer Scientific

200020444

Support a wide range of application...


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