25-043-942

CD43 Monoclonal Antibody (eBio84-3C1 (84-3C1)), PE-Cyanine7, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 25-043-942-Each-of-1 In Stock ₹ 26,951.40

25-043-942 - Each of 1

₹ 26,951.40

In Stock

Quantity

1

Base Price: ₹ 26,951.40

GST (18%): ₹ 4,851.252

Total Price: ₹ 31,802.652

Antigen

CD43

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P16150

Gene Symbols

SPN

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6693

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

eBio84-3C1 (84-3C1)

Conjugate

PE-Cyanine7

Gene

SPN

Gene Alias

3E8 antigen; A630014B01Rik; B-cell differentiation antigen LP-3; CD43; CD43 cytoplasmic tail; CD43-ct; Galactoglycoprotein; GALGP; gpL115; Leukocyte sialoglycoprotein; leukosialin; leukosianin; LOC101120462; LOW QUALITY PROTEIN: leukosialin; Lsn; Lsn1; Ly48; Ly-48; Lymphocyte antigen 48; sialophorin; sialophorin (gpL115, leukosialin, CD43); sialophorin gpL115; SPN; W3/13 antigen

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Related Products

Img

Invitrogen

50-125-78

--

Img

Invitrogen

50-112-4950

--

Img

Invitrogen

50-112-8624

--

Img

Invitrogen

25-146-942

--

Img

Invitrogen

25-057-842

--

Img

Invitrogen

50-112-8803

--

Img

Invitrogen

17-033-742

--

Img

Invitrogen

17-009-842

--

Description

  • The MAb ebio84-3C1 reacts with CD43, which is also known as leukosialin, galactoglycoprotein and sialophorin
  • CD43 is a sialomucin which like many mucins can have both adhesive and anti-adhesive functions
  • Expression of CD43 is found on most leukocytes except resting B lymphocytes
  • Proteolytic processing upon activation decreases surface expression
  • CD43 is involved in activation of T cells, B cells, NK cells, and monocytes
  • The counter-receptor for CD43 is CD169/SIGLEC-1, which is expressed on macrophages
  • CD43 (leukosialin, sialophorin) is a transmembrane mucin-like protein with high negative charge, expressed on the surface of most hematopoietic cells
  • CD43 contributes to a repulsive barrier that interferes with cellular adhesion, however, in certain cases also promotes leukocyte aggregation
  • By interaction with actin-binding proteins ezrin and moesin CD43 plays a regulatory role in remodeling T-cell morphology and regulates cell-cell interactions during lymphocyte traffic
  • CD43 signaling both enhances LFA-1 adhesiveness and counteracts LFA-1 induction via other receptors
  • Expression of CD43 causes induction of functionally active tumor suppressor p53 protein, but in case of p53 and ARF deficiency CD43 promotes tumor proliferation and viability
  • CD43 appears to be an important modulator of leukocyte functions
  • Diseases associated with CD43 dysfunction include Wiscott-Aldrich Syndrome and Adenoid Basal Cell Carcinoma.

Compare Similar Items

Show Difference

Img

Invitrogen

25-043-942

--


Antigen:
CD43

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P16150

Gene Symbols:
SPN

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6693

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
eBio84-3C1 (84-3C1)

Conjugate:
PE-Cyanine7

Gene:
SPN

Gene Alias:
3E8 antigen; A630014B01Rik; B-cell differentiation antigen LP-3; CD43; CD43 cytoplasmic tail; CD43-ct; Galactoglycoprotein; GALGP; gpL115; Leukocyte sialoglycoprotein; leukosialin; leukosianin; LOC101120462; LOW QUALITY PROTEIN: leukosialin; Lsn; Lsn1; Ly48; Ly-48; Lymphocyte antigen 48; sialophorin; sialophorin (gpL115, leukosialin, CD43); sialophorin gpL115; SPN; W3/13 antigen

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Fischer Scientific

25-044-380

--


Antigen:
LYVE1

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide, pH 7.2

Gene Accession No.:
Q8BHC0

Gene Symbols:
Lyve1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114332

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
ALY7

Conjugate:
PE-Cyanine7

Gene:
Lyve1

Gene Alias:
1200012G08Rik, cell surface retention sequence binding protein-1, cell surface retention sequence-binding protein 1, CRSBP1, CRSBP-1, extra cellular link domain-containing 1, extracellular link domain containing 1, extracellular link domain-containing 1, extracellular link domain-containing protein 1, HAR, hyaluronic acid receptor, lymphatic endothelial hyaluronan receptor LYVE-1, lymphatic vessel endothelial HA receptor-1, lymphatic vessel endothelial HA recptor-1, lymphatic vessel endothelial hyaluronan receptor 1, lymphatic vessel endothelial hyaluronic acid receptor 1, LYVE1, LYVE-1, sLyve 1, sLyve1, soluble LYVE 1, soluble LYVE1, UNQ230/PRO263, XLKD1

Host Species:
Rat

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Fischer Scientific

25-044-382

--


Antigen:
LYVE1

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide, pH 7.2

Gene Accession No.:
Q8BHC0

Gene Symbols:
Lyve1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114332

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
ALY7

Conjugate:
PE-Cyanine7

Gene:
Lyve1

Gene Alias:
1200012G08Rik, cell surface retention sequence binding protein-1, cell surface retention sequence-binding protein 1, CRSBP1, CRSBP-1, extra cellular link domain-containing 1, extracellular link domain containing 1, extracellular link domain-containing 1, extracellular link domain-containing protein 1, HAR, hyaluronic acid receptor, lymphatic endothelial hyaluronan receptor LYVE-1, lymphatic vessel endothelial HA receptor-1, lymphatic vessel endothelial HA recptor-1, lymphatic vessel endothelial hyaluronan receptor 1, lymphatic vessel endothelial hyaluronic acid receptor 1, LYVE1, LYVE-1, sLyve 1, sLyve1, soluble LYVE 1, soluble LYVE1, UNQ230/PRO263, XLKD1

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Invitrogen

25-047-942

--


Antigen:
CD47

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
Q08722

Gene Symbols:
CD47

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
961

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
B6H12

Conjugate:
PE-Cyanine7

Gene:
CD47

Gene Alias:
9130415E20Rik, AA407862, AI848868, antigen identified by monoclonal antibody 1D8, antigenic surface determinant protein OA3, AW108519, B430305P08Rik, Cd47, CD47 antigen, CD47 antigen (Rh-related antigen, integrin-associated signal transducer), CD47 antigen/integrin-associated protein, CD47 glycoprotein, CD47 molecule, CD47/IAP, IAP, integrin associated protein, integrin-associated protein, integrin-associated signal transducer, Itgp, Leukocyte surface antigen CD47, MER6, OA3, Protein MER6, Rh-related antigen, sCD47, soluble CD 47, soluble CD47

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ