25-049-280
CD49d (Integrin alpha 4) Monoclonal Antibody (R1-2), PE-Cyanine7, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 25-049-280-Each | In Stock | ₹ 6,643.73 |
25-049-280 - Each
In Stock
Quantity
1
Base Price: ₹ 6,643.73
GST (18%): ₹ 1,195.871
Total Price: ₹ 7,839.601
Antigen
CD49d (Integrin alpha 4)
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.
Q00651
Gene Symbols
ITGA4
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16401
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
R1-2
Conjugate
PE-Cyanine7
Gene
ITGA4
Gene Alias
269C wild type, alpha 4 subunit of VLA-4 receptor, antigen CD49D, alpha-4 subunit of VLA-4 receptor, CD49 antigen-like family member D, CD49d, IA4, integrin alpha 4, integrin alpha-4, integrin alpha4B, Integrin alpha-IV, integrin subunit alpha 4, integrin, alpha 4, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), Itga4, Itga4B, ITGA-IV, LPAM subunit alpha, lymphocyte Peyer patch adhesion molecules subunit alpha, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 receptor, alpha 4 subunit, VLA-4 subunit alpha
Host Species
Rat
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2b κ
Related Products
Description
- Description: The R1-2 monoclonal antibody reacts with mouse CD49d, the 150 kDa integrin alpha4 subunit
- The complex of CD49d non-covalently associated with integrin beta1 (CD29), also known as VLA-4, is a receptor for fibronectin and VCAM-1 (CD106)
- This complex is expressed by thymocytes, peripheral lymphocytes, monocytes and eosinophils
- CD49d also associates with integrin b7 and binds to the Mucosal vascular Addressin (MAdCAM-1)
- Applications Reported: This R1-2 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This R1-2 antibody has been tested by flow cytometric analysis of mouse splenocytes
- This may be used at less than or equal to 0.5 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Light sensitivity: This tandem dye is sensitive to photo-induced oxidation
- Please protect this vial and stained samples from light
- Fixation: Samples can be stored in IC Fixation Buffer (Product No
- 00-8222-49) (100 μL of cell sample + 100 μL of IC Fixation Buffer) or 1-step Fix/Lyse Solution (Product No
- 00-5333-57) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation
- The integrin alpha 4 (also known as CD49d and ITGA4) belongs to the integrin alpha chain family of proteins
- Integrins are heterodimeric integral membrane proteins composed of an alpha and beta chains
- Alpha4 chain associates with either beta1 or beta7 chain
- It has been demonstrated that the putative ligand-binding sites of both integrin alpha4beta1 and alpha4beta7 is located on the alpha4 chain
- These ligands included Madcam, VCAM, and fibronectin
- Madcam is known as the principal ligand for integrin alpha4beta7
- Recently it was also demonstrated that HIV-1 envelope can mimic Madcam by binding to and signaling though integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.
Compare Similar Items
Show Difference
Antigen: CD49d (Integrin alpha 4)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.: Q00651
Gene Symbols: ITGA4
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16401
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: R1-2
Conjugate: PE-Cyanine7
Gene: ITGA4
Gene Alias: 269C wild type, alpha 4 subunit of VLA-4 receptor, antigen CD49D, alpha-4 subunit of VLA-4 receptor, CD49 antigen-like family member D, CD49d, IA4, integrin alpha 4, integrin alpha-4, integrin alpha4B, Integrin alpha-IV, integrin subunit alpha 4, integrin, alpha 4, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), Itga4, Itga4B, ITGA-IV, LPAM subunit alpha, lymphocyte Peyer patch adhesion molecules subunit alpha, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 receptor, alpha 4 subunit, VLA-4 subunit alpha
Host Species: Rat
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
CD49d (Integrin alpha 4)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.:
Q00651
Gene Symbols:
ITGA4
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16401
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
R1-2
Conjugate:
PE-Cyanine7
Gene:
ITGA4
Gene Alias:
269C wild type, alpha 4 subunit of VLA-4 receptor, antigen CD49D, alpha-4 subunit of VLA-4 receptor, CD49 antigen-like family member D, CD49d, IA4, integrin alpha 4, integrin alpha-4, integrin alpha4B, Integrin alpha-IV, integrin subunit alpha 4, integrin, alpha 4, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), Itga4, Itga4B, ITGA-IV, LPAM subunit alpha, lymphocyte Peyer patch adhesion molecules subunit alpha, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 receptor, alpha 4 subunit, VLA-4 subunit alpha
Host Species:
Rat
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: CD49d (Integrin alpha 4)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.: Q00651
Gene Symbols: ITGA4
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16401
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: R1-2
Conjugate: PE-Cyanine7
Gene: ITGA4
Gene Alias: 269C wild type, alpha 4 subunit of VLA-4 receptor, antigen CD49D, alpha-4 subunit of VLA-4 receptor, CD49 antigen-like family member D, CD49d, IA4, integrin alpha 4, integrin alpha-4, integrin alpha4B, Integrin alpha-IV, integrin subunit alpha 4, integrin, alpha 4, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), Itga4, Itga4B, ITGA-IV, LPAM subunit alpha, lymphocyte Peyer patch adhesion molecules subunit alpha, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 receptor, alpha 4 subunit, VLA-4 subunit alpha
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
CD49d (Integrin alpha 4)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.:
Q00651
Gene Symbols:
ITGA4
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16401
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
R1-2
Conjugate:
PE-Cyanine7
Gene:
ITGA4
Gene Alias:
269C wild type, alpha 4 subunit of VLA-4 receptor, antigen CD49D, alpha-4 subunit of VLA-4 receptor, CD49 antigen-like family member D, CD49d, IA4, integrin alpha 4, integrin alpha-4, integrin alpha4B, Integrin alpha-IV, integrin subunit alpha 4, integrin, alpha 4, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), Itga4, Itga4B, ITGA-IV, LPAM subunit alpha, lymphocyte Peyer patch adhesion molecules subunit alpha, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 receptor, alpha 4 subunit, VLA-4 subunit alpha
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: CD56 (NCAM)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P13591
Gene Symbols: Ncam1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4684, 693789
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: TULY56
Conjugate: PE-Cyanine7
Gene: Ncam1
Gene Alias: adhesion molecule; antigen recognized by monoclonal antibody 5.1H11; Cd56; CD-56; CD56 120 kDa GPI-linked isoform; CD56 140 kDa isoform; CD56 140 kDa VASE isoform; E NCAM; E-NCAM; MSK39; N CAM1; NCAM; N-CAM; Ncam1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule; Neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; sCD56; sNCAM; soluble CD56; soluble NCAM
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human, Non-human Primate, Rhesus Monkey
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD56 (NCAM)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P13591
Gene Symbols:
Ncam1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4684, 693789
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
TULY56
Conjugate:
PE-Cyanine7
Gene:
Ncam1
Gene Alias:
adhesion molecule; antigen recognized by monoclonal antibody 5.1H11; Cd56; CD-56; CD56 120 kDa GPI-linked isoform; CD56 140 kDa isoform; CD56 140 kDa VASE isoform; E NCAM; E-NCAM; MSK39; N CAM1; NCAM; N-CAM; Ncam1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule; Neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; sCD56; sNCAM; soluble CD56; soluble NCAM
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate, Rhesus Monkey
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD58 (LFA-3)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: P19256
Gene Symbols: CD58
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 965
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: TS2/9
Conjugate: PE-Cyanine7
Gene: CD58
Gene Alias: Ag3, CD305, CD58, CD58 antigen, CD58 antigen, (lymphocyte function-associated antigen 3), CD58 molecule, FLJ23181, FLJ43722, LAIR1, LAIR-1, LFA3, LFA-3, Lymphocyte function-associated antigen 3, membrane receptor, RP5-1086K13.2, surface glycoprotein LFA-3
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD58 (LFA-3)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
P19256
Gene Symbols:
CD58
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
965
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
TS2/9
Conjugate:
PE-Cyanine7
Gene:
CD58
Gene Alias:
Ag3, CD305, CD58, CD58 antigen, CD58 antigen, (lymphocyte function-associated antigen 3), CD58 molecule, FLJ23181, FLJ43722, LAIR1, LAIR-1, LFA3, LFA-3, Lymphocyte function-associated antigen 3, membrane receptor, RP5-1086K13.2, surface glycoprotein LFA-3
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ