25-049-282
CD49d (Integrin alpha 4) Monoclonal Antibody (R1-2), PE-Cyanine7, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 25-049-282-Each-of-1 | In Stock | ₹ 31,143.84 |
25-049-282 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 31,143.84
GST (18%): ₹ 5,605.891
Total Price: ₹ 36,749.731
Antigen
CD49d (Integrin alpha 4)
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.
Q00651
Gene Symbols
ITGA4
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16401
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
R1-2
Conjugate
PE-Cyanine7
Gene
ITGA4
Gene Alias
269C wild type, alpha 4 subunit of VLA-4 receptor, antigen CD49D, alpha-4 subunit of VLA-4 receptor, CD49 antigen-like family member D, CD49d, IA4, integrin alpha 4, integrin alpha-4, integrin alpha4B, Integrin alpha-IV, integrin subunit alpha 4, integrin, alpha 4, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), Itga4, Itga4B, ITGA-IV, LPAM subunit alpha, lymphocyte Peyer patch adhesion molecules subunit alpha, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 receptor, alpha 4 subunit, VLA-4 subunit alpha
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2b κ
Related Products
Description
- Description: The R1-2 monoclonal antibody reacts with mouse CD49d, the 150 kDa integrin alpha4 subunit
- The complex of CD49d non-covalently associated with integrin beta1 (CD29), also known as VLA-4, is a receptor for fibronectin and VCAM-1 (CD106)
- This complex is expressed by thymocytes, peripheral lymphocytes, monocytes and eosinophils
- CD49d also associates with integrin b7 and binds to the Mucosal vascular Addressin (MAdCAM-1)
- Applications Reported: This R1-2 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This R1-2 antibody has been tested by flow cytometric analysis of mouse splenocytes
- This may be used at less than or equal to 0.5 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Light sensitivity: This tandem dye is sensitive to photo-induced oxidation
- Please protect this vial and stained samples from light
- Fixation: Samples can be stored in IC Fixation Buffer (Product No
- 00-8222-49) (100 μL of cell sample + 100 μL of IC Fixation Buffer) or 1-step Fix/Lyse Solution (Product No
- 00-5333-57) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation
- The integrin alpha 4 (also known as CD49d and ITGA4) belongs to the integrin alpha chain family of proteins
- Integrins are heterodimeric integral membrane proteins composed of an alpha and beta chains
- Alpha4 chain associates with either beta1 or beta7 chain
- It has been demonstrated that the putative ligand-binding sites of both integrin alpha4beta1 and alpha4beta7 is located on the alpha4 chain
- These ligands included Madcam, VCAM, and fibronectin
- Madcam is known as the principal ligand for integrin alpha4beta7
- Recently it was also demonstrated that HIV-1 envelope can mimic Madcam by binding to and signaling though integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.
Compare Similar Items
Show Difference
Antigen: CD49d (Integrin alpha 4)
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.: Q00651
Gene Symbols: ITGA4
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16401
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: R1-2
Conjugate: PE-Cyanine7
Gene: ITGA4
Gene Alias: 269C wild type, alpha 4 subunit of VLA-4 receptor, antigen CD49D, alpha-4 subunit of VLA-4 receptor, CD49 antigen-like family member D, CD49d, IA4, integrin alpha 4, integrin alpha-4, integrin alpha4B, Integrin alpha-IV, integrin subunit alpha 4, integrin, alpha 4, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), Itga4, Itga4B, ITGA-IV, LPAM subunit alpha, lymphocyte Peyer patch adhesion molecules subunit alpha, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 receptor, alpha 4 subunit, VLA-4 subunit alpha
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
CD49d (Integrin alpha 4)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.:
Q00651
Gene Symbols:
ITGA4
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16401
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
R1-2
Conjugate:
PE-Cyanine7
Gene:
ITGA4
Gene Alias:
269C wild type, alpha 4 subunit of VLA-4 receptor, antigen CD49D, alpha-4 subunit of VLA-4 receptor, CD49 antigen-like family member D, CD49d, IA4, integrin alpha 4, integrin alpha-4, integrin alpha4B, Integrin alpha-IV, integrin subunit alpha 4, integrin, alpha 4, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), Itga4, Itga4B, ITGA-IV, LPAM subunit alpha, lymphocyte Peyer patch adhesion molecules subunit alpha, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 receptor, alpha 4 subunit, VLA-4 subunit alpha
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: CD56 (NCAM)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P13591
Gene Symbols: Ncam1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4684, 693789
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: TULY56
Conjugate: PE-Cyanine7
Gene: Ncam1
Gene Alias: adhesion molecule; antigen recognized by monoclonal antibody 5.1H11; Cd56; CD-56; CD56 120 kDa GPI-linked isoform; CD56 140 kDa isoform; CD56 140 kDa VASE isoform; E NCAM; E-NCAM; MSK39; N CAM1; NCAM; N-CAM; Ncam1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule; Neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; sCD56; sNCAM; soluble CD56; soluble NCAM
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human, Non-human Primate, Rhesus Monkey
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD56 (NCAM)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P13591
Gene Symbols:
Ncam1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4684, 693789
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
TULY56
Conjugate:
PE-Cyanine7
Gene:
Ncam1
Gene Alias:
adhesion molecule; antigen recognized by monoclonal antibody 5.1H11; Cd56; CD-56; CD56 120 kDa GPI-linked isoform; CD56 140 kDa isoform; CD56 140 kDa VASE isoform; E NCAM; E-NCAM; MSK39; N CAM1; NCAM; N-CAM; Ncam1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule; Neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; sCD56; sNCAM; soluble CD56; soluble NCAM
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate, Rhesus Monkey
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD58 (LFA-3)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: P19256
Gene Symbols: CD58
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 965
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: TS2/9
Conjugate: PE-Cyanine7
Gene: CD58
Gene Alias: Ag3, CD305, CD58, CD58 antigen, CD58 antigen, (lymphocyte function-associated antigen 3), CD58 molecule, FLJ23181, FLJ43722, LAIR1, LAIR-1, LFA3, LFA-3, Lymphocyte function-associated antigen 3, membrane receptor, RP5-1086K13.2, surface glycoprotein LFA-3
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD58 (LFA-3)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
P19256
Gene Symbols:
CD58
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
965
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
TS2/9
Conjugate:
PE-Cyanine7
Gene:
CD58
Gene Alias:
Ag3, CD305, CD58, CD58 antigen, CD58 antigen, (lymphocyte function-associated antigen 3), CD58 molecule, FLJ23181, FLJ43722, LAIR1, LAIR-1, LFA3, LFA-3, Lymphocyte function-associated antigen 3, membrane receptor, RP5-1086K13.2, surface glycoprotein LFA-3
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD59 (Protectin)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: P13987
Gene Symbols: CD59
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 966
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: OV9A2
Conjugate: PE-Cyanine7
Gene: CD59
Gene Alias: 16.3A5, 1F5, 1F5 antigen, 20 kDa homologous restriction factor, AA987121, Cb59b molecule, CD59, CD59 antigen, CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344), CD59 glycoprotein, CD59 molecule, CD59 molecule (CD59 blood group), CD59 molecule, complement regulatory protein, Cd59a, CD59a antigen, CD59A glycoprotein, Cd59b, CD59b antigen, CD59B glycoprotein, CD59b moleucle, complement regulatory protein, complement inhibitor CD59, complement regulatory protein, EJ16, EJ30, EL32, G344, HRF20, HRF-20, human leukocyte antigen MIC11, Ly-6-like protein, lymphocytic antigen CD59/MEM43, MACIF, MAC-inhibitory protein, MACIP, MAC-IP, MEM43, MEM43 antigen, membrane attack complex (MAC) inhibition factor, membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20, protectin, surface anitgen recognized by monoclonal antibody 16.3A5, T cell-activating protein
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD59 (Protectin)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
P13987
Gene Symbols:
CD59
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
966
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
OV9A2
Conjugate:
PE-Cyanine7
Gene:
CD59
Gene Alias:
16.3A5, 1F5, 1F5 antigen, 20 kDa homologous restriction factor, AA987121, Cb59b molecule, CD59, CD59 antigen, CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344), CD59 glycoprotein, CD59 molecule, CD59 molecule (CD59 blood group), CD59 molecule, complement regulatory protein, Cd59a, CD59a antigen, CD59A glycoprotein, Cd59b, CD59b antigen, CD59B glycoprotein, CD59b moleucle, complement regulatory protein, complement inhibitor CD59, complement regulatory protein, EJ16, EJ30, EL32, G344, HRF20, HRF-20, human leukocyte antigen MIC11, Ly-6-like protein, lymphocytic antigen CD59/MEM43, MACIF, MAC-inhibitory protein, MACIP, MAC-IP, MEM43, MEM43 antigen, membrane attack complex (MAC) inhibition factor, membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20, protectin, surface anitgen recognized by monoclonal antibody 16.3A5, T cell-activating protein
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ