25-059-642
CD59 (Protectin) Monoclonal Antibody (OV9A2), PE-Cyanine7, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 25-059-642-Each-of-1 | In Stock | ₹ 31,229.40 |
25-059-642 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 31,229.40
GST (18%): ₹ 5,621.292
Total Price: ₹ 36,850.692
Antigen
CD59 (Protectin)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.
P13987
Gene Symbols
CD59
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
966
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
OV9A2
Conjugate
PE-Cyanine7
Gene
CD59
Gene Alias
16.3A5, 1F5, 1F5 antigen, 20 kDa homologous restriction factor, AA987121, Cb59b molecule, CD59, CD59 antigen, CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344), CD59 glycoprotein, CD59 molecule, CD59 molecule (CD59 blood group), CD59 molecule, complement regulatory protein, Cd59a, CD59a antigen, CD59A glycoprotein, Cd59b, CD59b antigen, CD59B glycoprotein, CD59b moleucle, complement regulatory protein, complement inhibitor CD59, complement regulatory protein, EJ16, EJ30, EL32, G344, HRF20, HRF-20, human leukocyte antigen MIC11, Ly-6-like protein, lymphocytic antigen CD59/MEM43, MACIF, MAC-inhibitory protein, MACIP, MAC-IP, MEM43, MEM43 antigen, membrane attack complex (MAC) inhibition factor, membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20, protectin, surface anitgen recognized by monoclonal antibody 16.3A5, T cell-activating protein
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
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Description
- Description: This OV9A2 monoclonal antibody reacts with human CD59, which is also known as Protectin
- This GPI-linked membrane glycoprotein shares structural homology with the murine Ly-6 superfamily
- CD59 is expressed on all human lymphocytes, monocytes, granulocytes, and erythrocytes
- This protein is also expressed on non-hematopoietic cells, including endothelial cells and neurons
- By binding the complement components C8 and C9, CD59 inhibits assembly of the membrane attack complex and cytolytic activity by complement
- CD59 interacts with CD2 to modulate T cell adhesion, and also plays a role in T cell activation
- Finally, altered expression of CD55 and CD59 on human peripheral blood cells has been observed in patients with systemic lupus erythematosus (SLE)
- Crossblocking studies indicate that the OV9A2 monoclonal antibody binds the same epitope as MEM-43
- Applications Reported: This OV9A2 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This OV9A2 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells
- This may be used at 5 μL (0.125 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Light sensitivity: This tandem dye is sensitive to photo-induced oxidation
- CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC)
- CD59 is the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade
- CD59 also associates with C5b-8 complex and counteracts appropriate formation of cytolytic pore within the plasma membrane
- Further, CD59 is a low-affinity ligand of human CD2, causes T cell costimulation, and is involved in lymphocyte signal transduction
- CD59 is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation
- Mutations in this gene cause CD59 deficiency, a disease involving hemolytic anemia, thrombosis, and cerebral infarction
- Multiple alternatively spliced transcript variants of CD59 have been identified.
Compare Similar Items
Show Difference
Antigen: CD59 (Protectin)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: P13987
Gene Symbols: CD59
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 966
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: OV9A2
Conjugate: PE-Cyanine7
Gene: CD59
Gene Alias: 16.3A5, 1F5, 1F5 antigen, 20 kDa homologous restriction factor, AA987121, Cb59b molecule, CD59, CD59 antigen, CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344), CD59 glycoprotein, CD59 molecule, CD59 molecule (CD59 blood group), CD59 molecule, complement regulatory protein, Cd59a, CD59a antigen, CD59A glycoprotein, Cd59b, CD59b antigen, CD59B glycoprotein, CD59b moleucle, complement regulatory protein, complement inhibitor CD59, complement regulatory protein, EJ16, EJ30, EL32, G344, HRF20, HRF-20, human leukocyte antigen MIC11, Ly-6-like protein, lymphocytic antigen CD59/MEM43, MACIF, MAC-inhibitory protein, MACIP, MAC-IP, MEM43, MEM43 antigen, membrane attack complex (MAC) inhibition factor, membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20, protectin, surface anitgen recognized by monoclonal antibody 16.3A5, T cell-activating protein
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD59 (Protectin)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
P13987
Gene Symbols:
CD59
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
966
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
OV9A2
Conjugate:
PE-Cyanine7
Gene:
CD59
Gene Alias:
16.3A5, 1F5, 1F5 antigen, 20 kDa homologous restriction factor, AA987121, Cb59b molecule, CD59, CD59 antigen, CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344), CD59 glycoprotein, CD59 molecule, CD59 molecule (CD59 blood group), CD59 molecule, complement regulatory protein, Cd59a, CD59a antigen, CD59A glycoprotein, Cd59b, CD59b antigen, CD59B glycoprotein, CD59b moleucle, complement regulatory protein, complement inhibitor CD59, complement regulatory protein, EJ16, EJ30, EL32, G344, HRF20, HRF-20, human leukocyte antigen MIC11, Ly-6-like protein, lymphocytic antigen CD59/MEM43, MACIF, MAC-inhibitory protein, MACIP, MAC-IP, MEM43, MEM43 antigen, membrane attack complex (MAC) inhibition factor, membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20, protectin, surface anitgen recognized by monoclonal antibody 16.3A5, T cell-activating protein
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD63
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P08962
Gene Symbols: CD63
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 967
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: H5C6
Conjugate: PE-Cyanine7
Gene: CD63
Gene Alias: C75951; CD 63; Cd63; CD63 antigen; CD63 antigen (melanoma 1 antigen); Cd63 molecule; CD63 protein; granulophysin; LAMP-3; Lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3; mast cell antigen AD1; ME491; melanoma 1 antigen; melanoma-associated antigen ME491; melanoma-associated antigen MLA1; MLA1; Ocular melanoma-associated antigen; OMA81H; Tetraspanin-30; TSPAN30; tspan-30
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD63
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P08962
Gene Symbols:
CD63
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
967
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
H5C6
Conjugate:
PE-Cyanine7
Gene:
CD63
Gene Alias:
C75951; CD 63; Cd63; CD63 antigen; CD63 antigen (melanoma 1 antigen); Cd63 molecule; CD63 protein; granulophysin; LAMP-3; Lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3; mast cell antigen AD1; ME491; melanoma 1 antigen; melanoma-associated antigen ME491; melanoma-associated antigen MLA1; MLA1; Ocular melanoma-associated antigen; OMA81H; Tetraspanin-30; TSPAN30; tspan-30
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD64
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: P12314
Gene Symbols: FCGR1A
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2209
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 10.1
Conjugate: PE-Cyanine7
Gene: FCGR1A
Gene Alias: AI323638, AV092959, CD64, CD64 antigen, CD64A, Fc fragment of IgG high affinity Ib receptor, Fc fragment of IgG receptor Ia, Fc fragment of IgG, high affinity Ia, receptor (CD64), Fc fragment of IgG, high affinity Ia, receptor for (CD64), Fc fragment of IgG, high affinity Ib, receptor for (CD64), Fc gamma receptor, Fc gamma receptor Ia, Fc receptor, IgG, high affinity I, Fcg1, Fc-gamma receptor 1, Fc-gamma receptor I A1, Fc-gamma RI, Fc-gamma RIA, FcgammaRI, FcgammaRIa, Fcgr1, FCGR1A, Fcgr1b, FcgRI, FCRI, FLJ18345, high affinity IgG Fc receptor, subunit beta, high affinity immunoglobulin gamma Fc receptor I, high-affinity immunoglobulin gamma Fc receptor I, IGFR1, IgG Fc receptor I, IgG high affinity Fc receptor, IGGHAFC, RP11-196G18.2
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD64
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
P12314
Gene Symbols:
FCGR1A
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2209
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
10.1
Conjugate:
PE-Cyanine7
Gene:
FCGR1A
Gene Alias:
AI323638, AV092959, CD64, CD64 antigen, CD64A, Fc fragment of IgG high affinity Ib receptor, Fc fragment of IgG receptor Ia, Fc fragment of IgG, high affinity Ia, receptor (CD64), Fc fragment of IgG, high affinity Ia, receptor for (CD64), Fc fragment of IgG, high affinity Ib, receptor for (CD64), Fc gamma receptor, Fc gamma receptor Ia, Fc receptor, IgG, high affinity I, Fcg1, Fc-gamma receptor 1, Fc-gamma receptor I A1, Fc-gamma RI, Fc-gamma RIA, FcgammaRI, FcgammaRIa, Fcgr1, FCGR1A, Fcgr1b, FcgRI, FCRI, FLJ18345, high affinity IgG Fc receptor, subunit beta, high affinity immunoglobulin gamma Fc receptor I, high-affinity immunoglobulin gamma Fc receptor I, IGFR1, IgG Fc receptor I, IgG high affinity Fc receptor, IGGHAFC, RP11-196G18.2
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD66a (CEACAM1)
Classification: Monoclonal
Concentration: __
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P31809
Gene Symbols: CEACAM1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: CC1
Conjugate: PE-Cyanine7
Gene: CEACAM1
Gene Alias: antigen CD66; ATP-dependent taurocolate-carrier protein; bb-1; BGP; BGP1; BGP-1; BGPI; BGPR; Biliary glycoprotein 1; biliary glycoprotein D; bone gamma-carboxyglutamic acid (Gla) protein; carcinoembryonic antigen 1; carcinoembryonic antigen 7; carcinoembryonic antigen related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); Cc1; C-CAM; C-CAM 105; Ccam1; CD66a; CD66a antigen; Cea1; Cea-1; Cea7; Cea-7; CEACAM1; CEA-related cell adhesion molecule 1; CEA-related cell adhesion molecule 1 (bone gamma-carboxyglutamic acid (Gla) protein) (osteocalcin); Cell-CAM 105; ecto-ATPase; GP110; hepatitis virus (MHV-4) susceptibility; hepatitis virus receptor; Hv2; Hv-2; mCEA1; Mhv-1; MHVR; MHV-R; MHVR1; mmCGM1; mmCGM1a; mmCGM2; murine hepatitis virus receptor; osteocalcin; pp120; pp120/ecto-ATPase
Host Species: Mouse
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD66a (CEACAM1)
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P31809
Gene Symbols:
CEACAM1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
CC1
Conjugate:
PE-Cyanine7
Gene:
CEACAM1
Gene Alias:
antigen CD66; ATP-dependent taurocolate-carrier protein; bb-1; BGP; BGP1; BGP-1; BGPI; BGPR; Biliary glycoprotein 1; biliary glycoprotein D; bone gamma-carboxyglutamic acid (Gla) protein; carcinoembryonic antigen 1; carcinoembryonic antigen 7; carcinoembryonic antigen related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); Cc1; C-CAM; C-CAM 105; Ccam1; CD66a; CD66a antigen; Cea1; Cea-1; Cea7; Cea-7; CEACAM1; CEA-related cell adhesion molecule 1; CEA-related cell adhesion molecule 1 (bone gamma-carboxyglutamic acid (Gla) protein) (osteocalcin); Cell-CAM 105; ecto-ATPase; GP110; hepatitis virus (MHV-4) susceptibility; hepatitis virus receptor; Hv2; Hv-2; mCEA1; Mhv-1; MHVR; MHV-R; MHVR1; mmCGM1; mmCGM1a; mmCGM2; murine hepatitis virus receptor; osteocalcin; pp120; pp120/ecto-ATPase
Host Species:
Mouse
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG1 κ