17-080-942

CD80 (B7-1) Monoclonal Antibody (2D10.4), APC, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 17-080-942-Each-of-1 In Stock ₹ 26,095.80

17-080-942 - Each of 1

₹ 26,095.80

In Stock

Quantity

1

Base Price: ₹ 26,095.80

GST (18%): ₹ 4,697.244

Total Price: ₹ 30,793.044

Antigen

CD80 (B7-1)

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.

P33681

Gene Symbols

CD80

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

941

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

2D10.4

Conjugate

APC

Gene

CD80

Gene Alias

Activation B7-1 antigen, B7, B7 protein, B7.1, B71, B7-1, B7-1 protein, B7-1 protein precursor, BB1, B-lymphocyte activation antigen B7, Cd28l, CD28LG, CD28LG1, CD80, Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1), CD80 anitgen, CD80 antigen, CD80 antigen (CD28 antigen ligand 1, B7-1 antigen), Cd80 molecule, CD80 protein precursor, costimulatory factor CD80, costimulatory molecule variant IgV-CD80, CTLA-4 counter-receptor B7.1, LAB7, Ly53, Ly-53, MIC17, sCD 80, sCD80, secreted B7-1 protein precursor, soluble CD 80, soluble CD80, T-cell costimulatory molecule, T-cell co-stimulatory protein B7-1, T-lymphocyte activation antigen CD80, TS/A-1, TSA1

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: The 2D10.4 monoclonal antibody reacts with human CD80 (B7-1), a 60 kDa member of the Ig superfamily
  • CD80 is expressed by activated B cells, macrophages and dendritic cells
  • In addition, activated T cells express this antigen
  • CD80 has high affinity for binding to two T cell surface antigens, CD28 and CD152 (CTLA-4)
  • The interaction of CD28 and CD152 with CD80 is crucial in T-B cell communication leading to activation of T and B cells, respectively
  • Applications Reported: This 2D10.4 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 2D10.4 antibody has been pre-diluted and tested by flow cytometric analysis of Daudi cell line
  • This may be used at 5 μL (1.0 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28, and of an inhibitory receptor CTLA-4 (CD152)
  • Both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, and both molecules can also substitute for each other in this process
  • CD80 is rapidly induced on the surface of in vitro activated B cells, with Epstein Barr Virus (EBV) transformed B cell lines, with Burkitts lymphoma cell lines, with freshly isolated follicular B lymphoma cells, T cells, and monocytes
  • The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells
  • Diseases associated with CD80 dysfunction include gallbladder squamous cell carcinoma and myocarditis.

Compare Similar Items

Show Difference

Img

Invitrogen

17-080-942

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Antigen:
CD80 (B7-1)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
P33681

Gene Symbols:
CD80

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
941

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
2D10.4

Conjugate:
APC

Gene:
CD80

Gene Alias:
Activation B7-1 antigen, B7, B7 protein, B7.1, B71, B7-1, B7-1 protein, B7-1 protein precursor, BB1, B-lymphocyte activation antigen B7, Cd28l, CD28LG, CD28LG1, CD80, Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1), CD80 anitgen, CD80 antigen, CD80 antigen (CD28 antigen ligand 1, B7-1 antigen), Cd80 molecule, CD80 protein precursor, costimulatory factor CD80, costimulatory molecule variant IgV-CD80, CTLA-4 counter-receptor B7.1, LAB7, Ly53, Ly-53, MIC17, sCD 80, sCD80, secreted B7-1 protein precursor, soluble CD 80, soluble CD80, T-cell costimulatory molecule, T-cell co-stimulatory protein B7-1, T-lymphocyte activation antigen CD80, TS/A-1, TSA1

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Img

National Marker™

17-082

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Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
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Content And Storage:
__

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
__

Primary or Secondary:
__

Target Species:
__

Product Type:
MSDS Poster - English

Isotype:
__

Img

PIP™

17-094-943

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Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
1000 Plugs/Cs.

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__

Img

MilliporeSigma™

17-100-32MI

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Antigen:
Trimethyl-Histone H3 (Lys36)α

Classification:
Monoclonal

Concentration:
__

Formulation:
Anti-Trimethyl-Histone H3 (Lys36) (rabbit monoclonal IgG). One vial containing 50μL of protein A purified IgG in a solution containing 0.07 M Tris-glycine, 0.105 M NaCl, pH 7.4, 0.035% sodium azide and 30% glycerol. Normal Rabbit IgG. One vial containing 125μg Rabbit IgG in 125μL of storage buffer containing 0.05% sodium azide. ChIP Primers, BDNF Intron. One vial containing 75μL of 5μM of each primer specific for human BDNF intron. FOR: ACCCCAACCTCTAACAGCATTA; REV: TGTCTCTCAGCAGTCTTGCATT

Gene Accession No.:
Q16695

Gene Symbols:
H3.4, H3/g, H3/t, H3FT, H3T, H3t, MGC126886, MGC126888, OTTHUMP00000037945

Purification Method:
Protein A purified

Regulatory Status:
RUO

Gene ID (Entrez):
NP_003484

Content And Storage:
-20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles

Form:
Purified

Applications:
ChIP Assay, Dot Blot, Functional Assay, Western Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
__

Host Species:
Rabbit

Quantity:
25 Assays

Primary or Secondary:
Primary

Target Species:
Chicken, Human

Product Type:
__

Isotype:
IgG