36-317-0282

CD170 (Siglec F) Monoclonal Antibody (1RNM44N), Brilliant Ultra Violet™ 395, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each 36-317-0282-Each In Stock ₹ 31,370.57

36-317-0282 - Each

₹ 31,370.57

In Stock

Quantity

1

Base Price: ₹ 31,370.57

GST (18%): ₹ 5,646.703

Total Price: ₹ 37,017.273

Antigen

CD170 (Siglec F)

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

Q920G3

Gene Symbols

Siglecf

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

233186

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

1RNM44N

Conjugate

Brilliant Ultraviolet 395

Gene

Siglecf

Gene Alias

CD170; CD33 antigen-like 2; CD33L2; mSiglec-F; OB-binding protein 2; OBBP2; OB-BP2; Obesity-binding protein 2; sialic acid binding Ig like lectin 5; sialic acid binding Ig-like lectin 5; sialic acid binding Ig-like lectin F; sialic acid-binding Ig-like lectin 5; Sialic acid-binding Ig-like lectin F; sialic acid-binding immunoglobulin-like lectin 5; sialic acid-binding lectin Siglec-F; Siglec; SIGLEC5; siglec-5; Siglecf; Siglec-F

Host Species

Rat

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2a κ

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Description

  • This 1RNM44N mAb recognizes mouse CD170, also known as Siglec F
  • Siglec F is a cell surface lectin belonging to the Ig superfamily that binds glycoconjugates containing sialic acids that are commonly found on various cell types
  • The cytoplasmic domain of Siglec F contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) that initiates intracellular signaling upon ligand binding
  • Siglec F is expressed mostly on eosinophils and alveolar macrophages and lower levels of this receptor have also been reported on immature myelomonocytic cells
  • Mouse Siglec F is a functional ortholog of human Siglec 8, however, unlike human Siglec 8, mouse Siglec F is not expressed on mast cells
  • This 1RNM44N antibody will recognize a formaldehyde-fixed epitope
  • Applications Reported: This 1RNM44N antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 1RNM44N antibody has been tested by flow cytometric analysis of mouse thioglycolate-elicited peritoneal exudate cells
  • BUV395 is a dye that emits at 395nm and is intended for use on cytometers equipped with an Ultraviolet (355nm) laser
  • When using two or more Super Bright, BV, BUV, or other polymer dye-conjugated antibodies in a staining panel, it is recommended to use Super Bright Complete Staining Buffer (SB-4401-42) or Brilliant Stain Buffer (00-4409-75) to minimize any non-specific polymer interactions
  • Excitation: 350nm; Emission: 395nm; Laser: Ultraviolet Laser
  • SIGLEC5 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells
  • This protein binds equally to alpha2,3-linked and alpha2,6-linked sialic acid
  • The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface
  • This molecule is expressed by monocytic/myeloid lineage cells
  • SIGLEC5 is found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus
  • It is expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation.

Compare Similar Items

Show Difference

Img

Invitrogen

36-317-0282

--


Antigen:
CD170 (Siglec F)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q920G3

Gene Symbols:
Siglecf

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
233186

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
1RNM44N

Conjugate:
Brilliant Ultraviolet 395

Gene:
Siglecf

Gene Alias:
CD170; CD33 antigen-like 2; CD33L2; mSiglec-F; OB-binding protein 2; OBBP2; OB-BP2; Obesity-binding protein 2; sialic acid binding Ig like lectin 5; sialic acid binding Ig-like lectin 5; sialic acid binding Ig-like lectin F; sialic acid-binding Ig-like lectin 5; Sialic acid-binding Ig-like lectin F; sialic acid-binding immunoglobulin-like lectin 5; sialic acid-binding lectin Siglec-F; Siglec; SIGLEC5; siglec-5; Siglecf; Siglec-F

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Invitrogen

36-320-0

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Antigen:
SH3GL3

Classification:
Polyclonal

Concentration:
0.25 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
O35180, Q62421

Gene Symbols:
Sh3gl3

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20408, 81921

Content And Storage:
-20°C

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
Sh3gl3

Gene Alias:
CNSA3; EEN-B2; Endophilin 3; endophilin A3; endophilin III; endophilin-3; Endophilin-A3; HsT19371; SH3 domain containing GRB2 like 3; SH3 domain containing GRB2 like 3, endophilin A3; SH3 domain containing GRB2 like endophilin A3; SH3 domain protein 2 C1; SH3 domain protein 2 C2; SH3 domain protein 2C; SH3 domain-containing GRB2-like protein 3; Sh3d2c; Sh3d2c1; Sh3d2c2; SH3-domain GRB2-like 3; Sh3gl3; SH3p13

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

36-320-0102

--


Antigen:
__

Classification:
__

Concentration:
12 to 18 mg/mL

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
Product is stable for a minimum of 3 months from date of shipment when stored at -20° C in a manual defrost freezer. For optimal stability, store at -80° C. Avoid freeze-thaw cycles.

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
1 mL

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__

Img

Fischer Scientific

36-320-0502

--


Antigen:
__

Classification:
__

Concentration:
12 to 18 mg/mL

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
Product is stable for a minimum of 3 months from date of shipment when stored at -20° C in a manual defrost freezer. For optimal stability, store at -80° C. Avoid freeze-thaw cycles.

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
5 mL

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__