37-410-0

SOCS1 Monoclonal Antibody (4H1), Invitrogen™

Manufacturer: Invitrogen

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Pack Size SKU Availability Price
Each of 1 37-410-0-Each-of-1 In Stock ₹ 38,502.00

37-410-0 - Each of 1

₹ 38,502.00

In Stock

Quantity

1

Base Price: ₹ 38,502.00

GST (18%): ₹ 6,930.36

Total Price: ₹ 45,432.36

Antigen

SOCS1

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.

O35716

Gene Symbols

Socs1

Immunogen

Recombinant protein derived from the N-terminal region of the mouse SOCS-1 (Suppressor of Cytokine Signaling-1, also known as SSI-1) protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG1 κ

Applications

ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

4H1

Conjugate

Unconjugated

Gene

Socs1

Gene Alias

CIS1; Cish1; Cish7; cytokine inducible SH2-containing protein 1; cytokine inducible SH2-containing protein 7; cytokine-inducible SH2 protein 1; JAB; JAK binding protein; JAK2-binding protein; JAK-binding protein; Socs1; SOCS-1; SSI1; SSI-1; STAT induced SH3 protein 1; STAT-induced STAT inhibitor 1; Suppressor of cytokine signaling 1; Tec-interacting protein 3; TIP3; TIP-3

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

12703

Content And Storage

-20°C

Form

Liquid

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Description

  • The Suppressor of cytokine signaling (SOCS) and cytokine-inducible SH2 proteins are a family of intracellular proteins which regulate the immune cell responses to cytokines
  • SOCS1 acts to suppress dendritic cell (DC) as well as T cell hyperactivation following cytokine signaling by inhibiting JAK tyrosine kinase, a kinase necessary for type I and II cytokine receptors to initiate signaling, by directly binding to the catalytic domain of the kinase
  • SOCS1 also possesses E3 ubiquitin protein ligase activity that results in the polyubiquitination of its target proteins and subsequent degradation by the proteosome
  • It is through this method that SOCS1 negatively regulates signaling by Toll-like receptors TLR2 and TLR4 by mediating the degradation of the TLR signaling adaptor protein TIRAP.

Compare Similar Items

Show Difference

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Invitrogen

37-410-0

--


Antigen:
SOCS1

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
O35716

Gene Symbols:
Socs1

Immunogen:
Recombinant protein derived from the N-terminal region of the mouse SOCS-1 (Suppressor of Cytokine Signaling-1, also known as SSI-1) protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
4H1

Conjugate:
Unconjugated

Gene:
Socs1

Gene Alias:
CIS1; Cish1; Cish7; cytokine inducible SH2-containing protein 1; cytokine inducible SH2-containing protein 7; cytokine-inducible SH2 protein 1; JAB; JAK binding protein; JAK2-binding protein; JAK-binding protein; Socs1; SOCS-1; SSI1; SSI-1; STAT induced SH3 protein 1; STAT-induced STAT inhibitor 1; Suppressor of cytokine signaling 1; Tec-interacting protein 3; TIP3; TIP-3

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12703

Content And Storage:
-20°C

Form:
Liquid

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Invitrogen

37-440-0

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Antigen:
EphA2

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
P29317, Q03145

Gene Symbols:
EPHA2

Immunogen:
Synthetic peptide derived from the C-terminal region of the human EphA2 Receptor protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
1C11A12

Conjugate:
Unconjugated

Gene:
EPHA2

Gene Alias:
ARCC2; AW545284; CTPA; CTPP1; CTRCT6; Eck; EPH receptor A2; Epha2; ephrin receptor EphA2; Ephrin type-A receptor 2; Epithelial cell kinase; epithelial cell receptor protein tyrosine kinase; I79_019726; Myk2; Sek2; Sek-2; soluble EPHA2 variant 1; tyrosine-protein kinase receptor ECK; Tyrosine-protein kinase receptor MPK-5; tyrosine-protein kinase receptor SEK-2

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
13836, 1969, 366492

Content And Storage:
-20°C

Form:
Liquid

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Invitrogen

37-450-0

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Antigen:
Connexin 47

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
Q8BQU6

Gene Symbols:
GJC2

Immunogen:
Synthetic peptide derived from the C-terminal region of the mouse Connexin 47 protein

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
4A11A2

Conjugate:
Unconjugated

Gene:
GJC2

Gene Alias:
B230382L12Rik; connexin 47 type A; connexin 47 type C; connexin 47 type D; connexin-46.6; Connexin-47; CX46.6; Cx47; CXG2; gap junction alpha-12 protein; Gap junction gamma-2 protein; gap junction membrane channel protein alpha 12; gap junction protein gamma 2; gap junction protein, alpha 12; gap junction protein, chi 2; gap junction protein, gamma 2; gap junction protein, gamma 2, 47kDa; GJA12; Gjc2; HLD2; LMPH1C; PMLDAR; SPG44

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
118454

Content And Storage:
-20°C

Form:
Liquid

Img

Fischer Scientific

37-462-5

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Antigen:
__

Classification:
__

Concentration:
__

Formulation:
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Gene Accession No.:
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Gene Symbols:
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Immunogen:
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Quantity:
25 mg

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
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Host Species:
__

Purification Method:
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Regulatory Status:
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Gene ID (Entrez):
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Content And Storage:
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Form:
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