38-520-0
SOCS1 Polyclonal Antibody, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 38-520-0-Each-of-1 | In Stock | ₹ 36,790.80 |
38-520-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,790.80
GST (18%): ₹ 6,622.344
Total Price: ₹ 43,413.144
Antigen
SOCS1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Socs1
Gene Alias
CIS1; Cish1; Cish7; cytokine inducible SH2-containing protein 1; cytokine inducible SH2-containing protein 7; cytokine-inducible SH2 protein 1; JAB; JAK binding protein; JAK2-binding protein; JAK-binding protein; Socs1; SOCS-1; SSI1; SSI-1; STAT induced SH3 protein 1; STAT-induced STAT inhibitor 1; Suppressor of cytokine signaling 1; Tec-interacting protein 3; TIP3; TIP-3
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12703, 8651
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.25 mg/mL
Formulation
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.
O15524, O35716
Gene Symbols
Socs1
Immunogen
Raised against the C-term of human SOCS1.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The Suppressor of cytokine signaling (SOCS) and cytokine-inducible SH2 proteins are a family of intracellular proteins which regulate the immune cell responses to cytokines
- SOCS1 acts to suppress dendritic cell (DC) as well as T cell hyperactivation following cytokine signaling by inhibiting JAK tyrosine kinase, a kinase necessary for type I and II cytokine receptors to initiate signaling, by directly binding to the catalytic domain of the kinase
- SOCS1 also possesses E3 ubiquitin protein ligase activity that results in the polyubiquitination of its target proteins and subsequent degradation by the proteosome
- It is through this method that SOCS1 negatively regulates signaling by Toll-like receptors TLR2 and TLR4 by mediating the degradation of the TLR signaling adaptor protein TIRAP.
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Antigen: SOCS1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Socs1
Gene Alias: CIS1; Cish1; Cish7; cytokine inducible SH2-containing protein 1; cytokine inducible SH2-containing protein 7; cytokine-inducible SH2 protein 1; JAB; JAK binding protein; JAK2-binding protein; JAK-binding protein; Socs1; SOCS-1; SSI1; SSI-1; STAT induced SH3 protein 1; STAT-induced STAT inhibitor 1; Suppressor of cytokine signaling 1; Tec-interacting protein 3; TIP3; TIP-3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12703, 8651
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.25 mg/mL
Formulation: PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.: O15524, O35716
Gene Symbols: Socs1
Immunogen: Raised against the C-term of human SOCS1.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
SOCS1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Socs1
Gene Alias:
CIS1; Cish1; Cish7; cytokine inducible SH2-containing protein 1; cytokine inducible SH2-containing protein 7; cytokine-inducible SH2 protein 1; JAB; JAK binding protein; JAK2-binding protein; JAK-binding protein; Socs1; SOCS-1; SSI1; SSI-1; STAT induced SH3 protein 1; STAT-induced STAT inhibitor 1; Suppressor of cytokine signaling 1; Tec-interacting protein 3; TIP3; TIP-3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12703, 8651
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.25 mg/mL
Formulation:
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.:
O15524, O35716
Gene Symbols:
Socs1
Immunogen:
Raised against the C-term of human SOCS1.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: SMAD1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SMAD1
Gene Alias: AI528653; BSP1; BSP-1; dwarfin-A; Dwf-A; DWFC; hSMAD1; JV41; JV4-1; JV5-1; MAD (mothers against decapentaplegic, Drosophila) homolog 1; MAD homolog 1; MAD homolog1 (mothers against decapentaplegic, Drosophila); MAD, mothers against decapentaplegic homolog 1; Madh1; MADH5; MADR1; Mad-related protein 1; Mlp1; mMad1; mothers against decapentaplegic homolog 1; mothers against DPP homolog 1; mothers-against-DPP-related 1; Mothers-against-DPP-related-1; MusMLP; OTTHUMP00000220456; SMAD; Smad 1; SMAD family member 1; SMAD, mothers against DPP homolog 1; Smad1; SMAD5; TGF-beta signaling protein 1; transforming growth factor-beta signaling protein 1; Transforming growth factor-beta-signaling protein 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17125, 4086
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.25 mg/mL
Formulation: PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.: P70340, Q15797
Gene Symbols: SMAD1
Immunogen: Synthetic peptide derived from an internal region of the human Smad1 protein.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate
Product Type: Antibody
Isotype: IgG
Antigen:
SMAD1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SMAD1
Gene Alias:
AI528653; BSP1; BSP-1; dwarfin-A; Dwf-A; DWFC; hSMAD1; JV41; JV4-1; JV5-1; MAD (mothers against decapentaplegic, Drosophila) homolog 1; MAD homolog 1; MAD homolog1 (mothers against decapentaplegic, Drosophila); MAD, mothers against decapentaplegic homolog 1; Madh1; MADH5; MADR1; Mad-related protein 1; Mlp1; mMad1; mothers against decapentaplegic homolog 1; mothers against DPP homolog 1; mothers-against-DPP-related 1; Mothers-against-DPP-related-1; MusMLP; OTTHUMP00000220456; SMAD; Smad 1; SMAD family member 1; SMAD, mothers against DPP homolog 1; Smad1; SMAD5; TGF-beta signaling protein 1; transforming growth factor-beta signaling protein 1; Transforming growth factor-beta-signaling protein 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17125, 4086
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.25 mg/mL
Formulation:
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.:
P70340, Q15797
Gene Symbols:
SMAD1
Immunogen:
Synthetic peptide derived from an internal region of the human Smad1 protein.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate
Product Type:
Antibody
Isotype:
IgG
Antigen: __
Classification: __
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Content And Storage: Protect from light
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Quantity: 10 mg
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Solid
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10 mg
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