3844148

CD11b Rat anti-Mouse, PE, Clone: M1/70, BD

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD11b

Concentration

0.2mg/mL

Classification

Monoclonal

Host Species

Rat

Target Species

Human, Mouse

Immunogen

Mouse Splenic Cells

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone

M1/70

Applications

Flow Cytometry

Conjugate

PE

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype

IgG2b κ

Purification Method

Affinity Purified

Description

Itgam; Integrin alpha-M; Ly-40; Mac-1a; Mac-1 alpha; CR3A; CR-3 alpha chain

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Description

  • The M1/70 antibody reacts with the 170kDa α[M] chain of Mac-1 (CD11b/CD18, α[M]β2 integrin), also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54)
  • Mac-1 is expressed at varying levels on granulocytes, macrophages, myeloid-derived dendritic cells, natural killer cells, microglia, and B-1 cells
  • Mac-1 expression is rapidly up-regulated on neutrophils after activation, in the same time period that CD62L (L-selectin) is shed from the cell surface
  • M1/70 antibody reportedly blocks cell adherence and C3bi binding, but it does not block cell-mediated lysis
  • Cross-reaction of mAb M1/70 with CD11b on human monocytes, polymorphonuclear leukocytes, and NK cells has been reported
  • This antibody is routinely tested by flow cytometric analysis
  • Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature
  • Host Species: Rat Clone: M1/70 Isotype: IgG2b, κ Cross Reactivity: Mouse Flow Cytometry

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Show Difference

Img

Fischer Scientific

3844148

Rat Monoclonal Antibody...


Antigen:
CD11b

Concentration:
0.2mg/mL

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Human, Mouse

Immunogen:
Mouse Splenic Cells

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
M1/70

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2b κ

Purification Method:
Affinity Purified

Description:
Itgam; Integrin alpha-M; Ly-40; Mac-1a; Mac-1 alpha; CR3A; CR-3 alpha chain

Img

Fischer Scientific

3844150

Rat Monoclonal Antibody...


Antigen:
CD19

Concentration:
0.5mg/mL

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Immunogen:
Mouse CD19 Transfected Cell Line

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
1D3

Applications:
Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Description:
__

Img

Fischer Scientific

3844150

Rat Monoclonal Antibody...


Antigen:
CD19

Concentration:
0.5mg/mL

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Immunogen:
Mouse CD19 Transfected Cell Line

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
1D3

Applications:
Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Description:
__

Img

Fischer Scientific

3844152

Rat Monoclonal Antibody...


Antigen:
CD19

Concentration:
0.2mg/mL

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Immunogen:
Mouse CD19 Transfected Cell Line

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
1D3

Applications:
Flow Cytometry

Conjugate:
PE

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Description:
__