3844150
CD19 Rat anti-Mouse, FITC, Clone: 1D3, BD
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD19
Concentration
0.5mg/mL
Classification
Monoclonal
Host Species
Rat
Target Species
Mouse
Immunogen
Mouse CD19 Transfected Cell Line
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone
1D3
Applications
Flow Cytometry
Conjugate
FITC
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype
IgG2a κ
Purification Method
Affinity Purified
Related Products
Description
- The 1D3 antibody reacts with CD19, a B lymphocyte-lineage differentiation antigen
- CD19, a 95kDa transmembrance glycoprotein, is a member of the immunoglobulin superfamily and is expressed throughout B-lymphocyte development from the pro-B cell through the mature B-cell stages
- Terminally differentiated plasma cells do not express CD19
- On the surface of mature B cells, the CD19 molecule associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to promote cellular activation
- Studies with CD19-deficient mice have suggested that the level of CD19 expression affects the generation and maturation of B cells in the bone marrow and periphery
- B-1 lineage B cells, also known as CD5+ B cells, are drastically reduced or absent in CD19-deficient mice
- Increased levels of CD19 expression correlate with increased frequencies of peritonal and splenic B-1 cells and reduced numbers of conventional B lymphocytes in the periphery
- CD19 participates in B-lymphocyte development, B-cell activation, maturation of memory B cells and regulation of tolerance
- CD19 has also been detected on peritoneal mast cells, co-localized with CD21/CD35, and it is proposed to play a role in complement-mediated mast-cell activation
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature
- Host Species: Rat Clone: 1D3 Isotype: IgG2a, κ Cross Reactivity: Mouse Flow Cytometry
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Antigen: CD19
Concentration: 0.5mg/mL
Classification: Monoclonal
Host Species: Rat
Target Species: Mouse
Immunogen: Mouse CD19 Transfected Cell Line
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: 1D3
Applications: Flow Cytometry
Conjugate: FITC
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG2a κ
Purification Method: Affinity Purified
Antigen:
CD19
Concentration:
0.5mg/mL
Classification:
Monoclonal
Host Species:
Rat
Target Species:
Mouse
Immunogen:
Mouse CD19 Transfected Cell Line
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
1D3
Applications:
Flow Cytometry
Conjugate:
FITC
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG2a κ
Purification Method:
Affinity Purified
Antigen: CD19
Concentration: 0.2mg/mL
Classification: Monoclonal
Host Species: Rat
Target Species: Mouse
Immunogen: Mouse CD19 Transfected Cell Line
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: 1D3
Applications: Flow Cytometry
Conjugate: PE
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG2a κ
Purification Method: Affinity Purified
Antigen:
CD19
Concentration:
0.2mg/mL
Classification:
Monoclonal
Host Species:
Rat
Target Species:
Mouse
Immunogen:
Mouse CD19 Transfected Cell Line
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
1D3
Applications:
Flow Cytometry
Conjugate:
PE
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG2a κ
Purification Method:
Affinity Purified
Antigen: CD195
Concentration: __
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Immunogen: Human CCR5 Transfected Cell Line
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: 2D7/CCR5
Applications: Flow Cytometry
Conjugate: APC-Cyanine7
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Isotype: IgG2a κ
Purification Method: Affinity Purified
Antigen:
CD195
Concentration:
__
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Immunogen:
Human CCR5 Transfected Cell Line
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
2D7/CCR5
Applications:
Flow Cytometry
Conjugate:
APC-Cyanine7
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Isotype:
IgG2a κ
Purification Method:
Affinity Purified
Antigen: NKp46
Concentration: __
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Immunogen: Human NKp46 Recombinant Protein
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Clone: 9E2/NKP46
Applications: Flow Cytometry
Conjugate: Unconjugated
Regulatory Status: RUO
Formulation: __
Isotype: IgG1 κ
Purification Method: Affinity Purified
Antigen:
NKp46
Concentration:
__
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Immunogen:
Human NKp46 Recombinant Protein
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Clone:
9E2/NKP46
Applications:
Flow Cytometry
Conjugate:
Unconjugated
Regulatory Status:
RUO
Formulation:
__
Isotype:
IgG1 κ
Purification Method:
Affinity Purified