3844400
CD195 Mouse anti-Human, APC-Cy7, Clone: 2D7/CCR5, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD195
Applications
Flow Cytometry
Conjugate
APC-Cyanine7
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Isotype
IgG2a κ
Purification Method
Affinity Purified
Description
CCR5; C-C chemokine receptor type 5; CC-CKR-5; CKR5; CHEMR13
Clone
2D7/CCR5
Classification
Monoclonal
Host Species
Mouse
Target Species
Human
Immunogen
Human CCR5 Transfected Cell Line
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- Reacts with the chemokine receptor, CCR5, a seven transmembrane-spanning G protein-associated molecule
- CCR5 belongs to the β chemokine receptor family
- It is expressed on a subset of T lymphocytes (CD3+, CD45RO+, CD95+)
- CCR5 regulates lymphocyte chemotaxis activation and transendothelial migration during inflammation
- It signals a response to at least three chemokines: RANTES and macrophage inflammatory protein-1 (MIP-1) α and β
- Additionally, CCR5 has been found to be a co-receptor for macrophage-tropic HIV-1 on CD4+ cells, a characteristic that is important in viral transmission
- Reports indicate that individuals who have partial (heterozygous) or complete (homozygous) deletion of the CCR5 allele, demonstrate resistance to HIV infection
- This antibody has been shown to block ligand and gp120 binding
- It is also able to neutralize HIV infection
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature
- Host Species: Mouse Clone: 2D7/CCR5 Isotype: IgG2a, κ Species Reactivity: Human Flow Cytometry, Functional Assay, Immunofluorescence
Compare Similar Items
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Antigen: CD195
Applications: Flow Cytometry
Conjugate: APC-Cyanine7
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Isotype: IgG2a κ
Purification Method: Affinity Purified
Description: CCR5; C-C chemokine receptor type 5; CC-CKR-5; CKR5; CHEMR13
Clone: 2D7/CCR5
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Immunogen: Human CCR5 Transfected Cell Line
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD195
Applications:
Flow Cytometry
Conjugate:
APC-Cyanine7
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Isotype:
IgG2a κ
Purification Method:
Affinity Purified
Description:
CCR5; C-C chemokine receptor type 5; CC-CKR-5; CKR5; CHEMR13
Clone:
2D7/CCR5
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Immunogen:
Human CCR5 Transfected Cell Line
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: NKp46
Applications: Flow Cytometry
Conjugate: Unconjugated
Regulatory Status: RUO
Formulation: __
Isotype: IgG1 κ
Purification Method: Affinity Purified
Description: __
Clone: 9E2/NKP46
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Immunogen: Human NKp46 Recombinant Protein
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
NKp46
Applications:
Flow Cytometry
Conjugate:
Unconjugated
Regulatory Status:
RUO
Formulation:
__
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Description:
__
Clone:
9E2/NKP46
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Immunogen:
Human NKp46 Recombinant Protein
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: __
Applications: __
Conjugate: __
Regulatory Status: __
Formulation: __
Isotype: __
Purification Method: __
Description: __
Clone: __
Classification: __
Host Species: __
Target Species: __
Immunogen: __
Primary or Secondary: __
Content And Storage: __
Antigen:
__
Applications:
__
Conjugate:
__
Regulatory Status:
__
Formulation:
__
Isotype:
__
Purification Method:
__
Description:
__
Clone:
__
Classification:
__
Host Species:
__
Target Species:
__
Immunogen:
__
Primary or Secondary:
__
Content And Storage:
__
Antigen: CD194
Applications: Flow Cytometry
Conjugate: PE-Cyanine7
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG1 κ
Purification Method: Affinity Purified
Description: CCR4; C-C chemokine receptor type 4; CMKBR4; K5-5
Clone: 1G1
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Immunogen: Human CCR4 Transfected Cell Line
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD194
Applications:
Flow Cytometry
Conjugate:
PE-Cyanine7
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Description:
CCR4; C-C chemokine receptor type 4; CMKBR4; K5-5
Clone:
1G1
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Immunogen:
Human CCR4 Transfected Cell Line
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.