3850488

Nucleoporin p62 Mouse, Unlabeled, Clone: 53, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Nucleoporin p62

Concentration

250μg/mL

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cell Biology

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype

IgG2b

Purification Method

Affinity Purified

Clone

53

Applications

Western Blot

Conjugate

Unconjugated

Regulatory Status

RUO

Target Species

Chicken, Human, Mouse, Rat

Immunogen

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • The nuclear pore complex (NPC) acts as a gate to mediate active transport of proteins and RNA into and out of the nucleus
  • Proteins actively transported into the nucleus through the NPC require specific nuclear localization sequences
  • Many of these nucleoporins contain N-acetylglucosamine (GlcNAc) residues that are O-linked to serine or threonine
  • p62 is the best characterized member of a group of nucleoporins that line the central region of the NPC
  • A tightly associated complex is formed by p62 and two other nucleoporins, p54 and p58
  • p54 binds to a carboxy-terminal coiled-coil domain of p62 and p58 binds to a dimer of p54
  • The amino-terminal domain of p62 contains a series of XFXFX repeats and is joined to the coiled-coil domain by a threonine-rich linker segment
  • The major role of p62 is maintenance of the structural integrity of NPCs.

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3850488

Mouse Monoclonal Antibody...


Antigen:
Nucleoporin p62

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG2b

Purification Method:
Affinity Purified

Clone:
53

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Chicken, Human, Mouse, Rat

Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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250μg/mL

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Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1

Purification Method:
Affinity Purified

Clone:
29

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Mouse

Immunogen:
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Primary or Secondary:
Primary

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Concentration:
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Classification:
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Host Species:
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Research Discipline:
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Formulation:
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Isotype:
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Purification Method:
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Clone:
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Applications:
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Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Canine, Human, Mouse, Rat

Immunogen:
Rat GM130 aa. 869-982

Primary or Secondary:
Primary

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