3851642
Flotillin-1 Mouse, Unlabeled, Clone: 18, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Flotillin-1
Concentration
250μg/mL
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Cell Biology
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype
IgG1
Purification Method
Affinity Purified
Clone
18
Applications
Western Blot
Conjugate
Unconjugated
Regulatory Status
RUO
Target Species
Chicken, Human, Mouse, Rat
Immunogen
Mouse Flotillin aa. 312-428
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
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Description
- Caveolae are specialized membrane invaginations of 50-100 nm present in all cells, but abundant in endothelium, muscle cells, and adipocytes
- These plasma membrane microdomains function in transcytosis of macromolecules, and are the sites of potocytosis, where small molecules are concentrated and transferred inside the cells by glycosylphosphatidylinositol (GPI)-linked receptors
- Caveolin, a 22kDa protein and a well known marker for these plasma membrane microdomains, plays a structural role in these specializations
- Flotillin-1 was isolated from the Triton X-100 insoluble buoyant fraction, characteristic of caveolae
- Although the mRNA expression of both Flotillin-1 and Caveolin is very similar, Caveolin is undetectable in brain, while Flotillin-1 is very abundant
- Flotillin-1 is a close homolog of the Epidermal Surface Antigen (ESA/Flotillin-2), which also colocalizes in the caveolae
- Thus, Flotillin-1 and its relative ESA/Flotillin-2 are now incorporated into the expanding list of proteins co-localized at the caveolae which includes PKCα, Ras, Rap Src-like kinases, Gαβγ,and GPI-linked receptors
- Immunofluorescence, Immunoprecipitation, Western Blotting
Compare Similar Items
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Antigen: Flotillin-1
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Clone: 18
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Chicken, Human, Mouse, Rat
Immunogen: Mouse Flotillin aa. 312-428
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Flotillin-1
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Clone:
18
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Chicken, Human, Mouse, Rat
Immunogen:
Mouse Flotillin aa. 312-428
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: HAX-1
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Clone: 52
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Human, Mouse, Rat
Immunogen: Human HAX-1 aa. 10-148
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
HAX-1
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Clone:
52
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Human, Mouse, Rat
Immunogen:
Human HAX-1 aa. 10-148
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: p62 Ick ligand
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG1 κ
Purification Method: Affinity Purified
Clone: 3
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Human
Immunogen: Human p62 lck ligand aa. 257-437
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
p62 Ick ligand
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Clone:
3
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Human
Immunogen:
Human p62 lck ligand aa. 257-437
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: p62 Ick ligand
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG1 κ
Purification Method: Affinity Purified
Clone: 3
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Human
Immunogen: Human p62 lck ligand aa. 257-437
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
p62 Ick ligand
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Clone:
3
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Human
Immunogen:
Human p62 lck ligand aa. 257-437
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.