3851614

α-Synuclein Mouse, Unlabeled, Clone: 42, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

α-Synuclein

Concentration

250μg/mL

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cell Biology

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype

IgG1

Purification Method

Affinity Purified

Clone

42

Applications

Western Blot

Conjugate

Unconjugated

Regulatory Status

RUO

Target Species

Human, Mouse, Rat

Immunogen

Rat Synuclein-1 aa. 15-123

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • Synuclein cDNA was isolated from Torpedo californica and found to encode a 143 amino acid neuron-specific protein
  • In addition, a rat brain cDNA library yielded several clones that encode different proteins with homology to Torpedo Synuclein
  • A 140 amino acid protein in rat is referred to as Synuclein-1
  • In situ hybridization shows synuclein mRNAs in discrete areas of rat brain, notably the hippocampus
  • In humans, two synuclein proteins of 140 and 134 amino acids were sequenced that exhibit a high degree of homology with each other (61% identity) and with previously described Synuclein proteins
  • The 140 amino acid protein (α-Synuclein) is the human homologue of rat Synuclein-1 and is identical to the non-amyloid-β component precursor (NACP), a presynaptic protein involved in amyloidogenesis in Alzheimer's disease (AD)
  • The 134 amino acid protein (β-Synuclein) is the human homologue of bovine phosphoneuroprotein
  • These proteins are expressed in brain, primarily in presynaptic nerve terminals
  • Although the exact function of the Synucleins has not been determined, they have been linked to the prominent neurodegenerative disorders AD and Parkinson's disease
  • Immunofluorescence, Immunoprecipitation, Western Blotting

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Fischer Scientific

3851614

Mouse Monoclonal Antibody...


Antigen:
α-Synuclein

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1

Purification Method:
Affinity Purified

Clone:
42

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat

Immunogen:
Rat Synuclein-1 aa. 15-123

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Fischer Scientific

3851642

Mouse Monoclonal Antibody...


Antigen:
Flotillin-1

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1

Purification Method:
Affinity Purified

Clone:
18

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Chicken, Human, Mouse, Rat

Immunogen:
Mouse Flotillin aa. 312-428

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Mouse Monoclonal Antibody...


Antigen:
HAX-1

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1

Purification Method:
Affinity Purified

Clone:
52

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat

Immunogen:
Human HAX-1 aa. 10-148

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Mouse Monoclonal Antibody...


Antigen:
p62 Ick ligand

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Clone:
3

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Human

Immunogen:
Human p62 lck ligand aa. 257-437

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.