3851577

NAT1 Mouse, Unlabeled, Clone: 35, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

NAT1

Concentration

250μg/mL

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cell Biology

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype

IgG1

Purification Method

Affinity Purified

Description

Novel APOBEC-1 Target no. 1; DAP-5; Death Associated Protein -5

Clone

35

Applications

Immunofluorescence, Western Blot

Conjugate

Unconjugated

Regulatory Status

RUO

Target Species

Bovine, Canine, Human, Mouse, Rat

Immunogen

Human NAT1 aa. 672-830

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • eIF-4 proteins are required for recognition of mRNA and acceleration of protein translation
  • This group of proteins consists of the RNA helicase eIF-4A, the RNA-binding protein eIF-4B, the cap-binding protein eIF-4E, and eIF-4G (p220)
  • NAT1 (Novel APOBEC-1 Target no
  • 1), also known as DAP-5 (Death Associated Protein -5), is homologous to eIF-4G
  • Amino acid sequence comparison of NAT1 and eIF-4 shows that NAT1 lacks an eIF-4G N-terminal region
  • This region mediates eIF-4G association with eIF-4E
  • The highest degree of homology is within the central portions of NAT1 and eIF-4G, while the lowest degree of homology occurs at the C-terminus
  • NAT1 more closely resembles a cleaved form of eIF-4G that is involved in cap-independent translation
  • It is thought that NAT1 is involved in the repression of translation via its inhibition of both cap-dependent and cap-independent translation
  • Immunofluorescence, Immunoprecipitation, Western Blotting

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Show Difference

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Fischer Scientific

3851577

Mouse Monoclonal Antibody...


Antigen:
NAT1

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1

Purification Method:
Affinity Purified

Description:
Novel APOBEC-1 Target no. 1; DAP-5; Death Associated Protein -5

Clone:
35

Applications:
Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Bovine, Canine, Human, Mouse, Rat

Immunogen:
Human NAT1 aa. 672-830

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Concentration:
250μg/mL

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Host Species:
Mouse

Research Discipline:
Cell Biology

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Isotype:
IgG2b

Purification Method:
Affinity Purified

Description:
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Clone:
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Applications:
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Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
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Immunogen:
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Concentration:
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Classification:
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Host Species:
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Research Discipline:
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Formulation:
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Isotype:
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Purification Method:
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Description:
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Clone:
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Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat

Immunogen:
Human Carboxypeptidase E aa. 49-200

Primary or Secondary:
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Store undiluted at -20°C.

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Antigen:
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Concentration:
250μg/mL

Classification:
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Host Species:
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Research Discipline:
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Formulation:
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Isotype:
IgG1

Purification Method:
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Description:
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Clone:
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Applications:
Western Blot

Conjugate:
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Regulatory Status:
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Target Species:
Canine, Human, Mouse, Rat

Immunogen:
Mouse MEF2D aa. 346-511

Primary or Secondary:
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Content And Storage:
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