3851757
IAK1 Mouse, Unlabeled, Clone: 4, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
IAK1
Concentration
250μg/mL
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Cell Biology
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype
IgG1
Purification Method
Affinity Purified
Description
Aurora-A Kinase
Clone
4
Applications
Western Blot
Conjugate
Unconjugated
Regulatory Status
RUO
Target Species
Human, Mouse, Rat
Immunogen
Mouse IAK1 aa. 8-116
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
Description
- Cell division is a tightly regulated process that ensures the segregation of chromosomes into daughter cells
- Essential to this regulation is the modification of cell cycle components by reversible phosphorylation
- Ipl1 and aurora are two related kinases isolated from S.cerevisiae and Drosophila, respectively
- Inactivation of these kinases results in abnormal chromosome segregation and disruption of the centrosome
- A structurally and functionally similar kinase, IAK1 (Ipl1- and Aurora-related kinase 1), is a regulator of mammalian chromosome segregation
- Although IAK1 may be present in the cytoplasm, it is detected on the centrosome following duplication and also associates with the spindle microtubules from metaphase through cell division
- Expression of IAK1 is stringently regulated during the cell cycle
- Both mRNA and protein are initially expressed in S-phase, are elevated during M-phase, and are undetectable following completion of mitosis
- Increasing evidence suggests that IAK1 belongs to a novel subfamily of the ser/thr kinase superfamily
- Although mutational analysis of IAK1 will directly determine its function, it appears to be a key player in the control of cell division
- Immunofluorescence, Western Blotting
Compare Similar Items
Show Difference
Antigen: IAK1
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Description: Aurora-A Kinase
Clone: 4
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Human, Mouse, Rat
Immunogen: Mouse IAK1 aa. 8-116
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
IAK1
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Description:
Aurora-A Kinase
Clone:
4
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Human, Mouse, Rat
Immunogen:
Mouse IAK1 aa. 8-116
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: HIF-1α
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG1 κ
Purification Method: Affinity Purified
Description: MOP1
Clone: 54
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Human
Immunogen: Human HIF-1α aa. 610-727
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
HIF-1α
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Description:
MOP1
Clone:
54
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Human
Immunogen:
Human HIF-1α aa. 610-727
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: mGluR1
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Description: Metabotropic Glutamate Receptor-1
Clone: 20
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Mouse, Rat
Immunogen: Rat mGluR1 aa. 1042-1160
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
mGluR1
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Description:
Metabotropic Glutamate Receptor-1
Clone:
20
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Mouse, Rat
Immunogen:
Rat mGluR1 aa. 1042-1160
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: PKA[C]
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG2b
Purification Method: Affinity Purified
Description: __
Clone: 5B
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Canine, Human, Mouse, Rat
Immunogen: Human PKA[Cα] subunit aa. 18-347
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
PKA[C]
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG2b
Purification Method:
Affinity Purified
Description:
__
Clone:
5B
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Canine, Human, Mouse, Rat
Immunogen:
Human PKA[Cα] subunit aa. 18-347
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.