3853281
CD123 Mouse anti-Human, FITC, Clone: 7G3, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD123
Applications
Flow Cytometry
Conjugate
FITC
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype
IgG2a κ
Purification Method
Affinity Purified
Description
IL3RA; IL-3RA; IL-3Rα; IL-3R-alpha; Interleukin-3 receptor subunit alpha
Clone
7G3
Classification
Monoclonal
Host Species
Mouse
Target Species
Human
Immunogen
Human IL-3Ra-transfected cells
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- Reacts with human CD123, the 70kDa IL-3 receptor α chain (IL-3Rα), which associates with the 120-140kDa β subunit
- The β chain is shared with the receptors for interleukins IL-5 and GM-CSF
- IL-3Rα is expressed on hematopoietic progenitors and plays an important role in hematopoietic progenitor cell growth and differentiation
- This antibody has been reported to block the binding of 125I-IL-3 to high and low affinity IL-3 receptors
- In functional experiments, this antibody was found to inhibit acute myeloid leukemia cell proliferation, basophil histamine release, endothelial cell-mediated IL-8 secretion, and neutrophil transmigration
- This antibody has been reported to be useful for immunoprecipitation, western blot and immunofluorescent staining for flow cytometry
- At the Fifth HLDA Workshop, the human IL-3 receptor was designated CD123.
Compare Similar Items
Show Difference
Antigen: CD123
Applications: Flow Cytometry
Conjugate: FITC
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype: IgG2a κ
Purification Method: Affinity Purified
Description: IL3RA; IL-3RA; IL-3Rα; IL-3R-alpha; Interleukin-3 receptor subunit alpha
Clone: 7G3
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Immunogen: Human IL-3Ra-transfected cells
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD123
Applications:
Flow Cytometry
Conjugate:
FITC
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype:
IgG2a κ
Purification Method:
Affinity Purified
Description:
IL3RA; IL-3RA; IL-3Rα; IL-3R-alpha; Interleukin-3 receptor subunit alpha
Clone:
7G3
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Immunogen:
Human IL-3Ra-transfected cells
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD123
Applications: Flow Cytometry
Conjugate: PerCP-Cyanine5.5
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype: IgG2a κ
Purification Method: __
Description: IL3RA; IL-3RA; IL-3Rα; IL-3R-alpha; Interleukin-3 receptor subunit alpha
Clone: 7G3
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Immunogen: Human IL-3Ra-transfected cells
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD123
Applications:
Flow Cytometry
Conjugate:
PerCP-Cyanine5.5
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype:
IgG2a κ
Purification Method:
__
Description:
IL3RA; IL-3RA; IL-3Rα; IL-3R-alpha; Interleukin-3 receptor subunit alpha
Clone:
7G3
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Immunogen:
Human IL-3Ra-transfected cells
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: __
Applications: __
Conjugate: __
Regulatory Status: __
Formulation: __
Isotype: __
Purification Method: __
Description: __
Clone: __
Classification: __
Host Species: __
Target Species: __
Immunogen: __
Primary or Secondary: __
Content And Storage: __
Antigen:
__
Applications:
__
Conjugate:
__
Regulatory Status:
__
Formulation:
__
Isotype:
__
Purification Method:
__
Description:
__
Clone:
__
Classification:
__
Host Species:
__
Target Species:
__
Immunogen:
__
Primary or Secondary:
__
Content And Storage:
__
Antigen: CD11c
Applications: Flow Cytometry
Conjugate: APC
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype: IgG1 κ
Purification Method: Affinity Purified
Description: ITGAX; AlphaX integrin chain; Axb2; Integrin alpha-X; CR4; Leu M5; SLEB6
Clone: __
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Immunogen: Spleen Cells from Human with Hairy Cell Leukemia
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD11c
Applications:
Flow Cytometry
Conjugate:
APC
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Description:
ITGAX; AlphaX integrin chain; Axb2; Integrin alpha-X; CR4; Leu M5; SLEB6
Clone:
__
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Immunogen:
Spleen Cells from Human with Hairy Cell Leukemia
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.