3969093
CD19 Rat anti-Mouse, APC, Clone: 1D3, BD
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD19
Concentration
0.2mg/mL
Classification
Monoclonal
Host Species
Rat
Target Species
Mouse
Immunogen
Mouse CD19 Transfected Cell Line
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone
1D3
Applications
Flow Cytometry
Conjugate
APC
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype
IgG2a κ
Purification Method
Affinity Purified
Description
- The 1D3 antibody reacts with CD19, a B lymphocyte-lineage differentiation antigen
- CD19, a 95-kDa transmembrance glycoprotein, is a member of the immunoglobulin superfamily and is expressed throughout B-lymphocyte development from the pro-B cell throughthe mature B-cell stages
- Terminally differentiated plasma cells do not express CD19
- On the surface of mature B cells, the CD19 molecule associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to promote cellular activation
- Studies with CD19-deficient mice have suggested that the level of CD19 expression affects the generation and maturation of B cells in the bone marrow and periphery
- B-1 lineage B cells, also known as CD5+ B cells, are drastically reduced or absent in CD19-deficient mice
- Increased levels of CD19 expression correlate with increased frequencies of peritonal and splenic B-1 cells and reduced numbers of conventional B lymphocytes in the periphery
- CD19 participates in B-lymphocyte development, B-cell activation, maturation of memory B cells and regulation of tolerance
- CD19 has also been detected on peritoneal mast cells, co-localized with CD21/CD35, and it is proposed to play a role in complement-mediated mast-cell activation.
Compare Similar Items
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Antigen: CD19
Concentration: 0.2mg/mL
Classification: Monoclonal
Host Species: Rat
Target Species: Mouse
Immunogen: Mouse CD19 Transfected Cell Line
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: 1D3
Applications: Flow Cytometry
Conjugate: APC
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG2a κ
Purification Method: Affinity Purified
Antigen:
CD19
Concentration:
0.2mg/mL
Classification:
Monoclonal
Host Species:
Rat
Target Species:
Mouse
Immunogen:
Mouse CD19 Transfected Cell Line
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
1D3
Applications:
Flow Cytometry
Conjugate:
APC
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG2a κ
Purification Method:
Affinity Purified
Antigen: CD19
Concentration: 0.2mg/mL
Classification: Monoclonal
Host Species: Rat
Target Species: Mouse
Immunogen: Mouse CD19 Transfected Cell Line
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: 1D3
Applications: Flow Cytometry
Conjugate: APC-H7
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Isotype: IgG2a κ
Purification Method: Affinity Purified
Antigen:
CD19
Concentration:
0.2mg/mL
Classification:
Monoclonal
Host Species:
Rat
Target Species:
Mouse
Immunogen:
Mouse CD19 Transfected Cell Line
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
1D3
Applications:
Flow Cytometry
Conjugate:
APC-H7
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Isotype:
IgG2a κ
Purification Method:
Affinity Purified
Antigen: CD19
Concentration: __
Classification: Monoclonal
Host Species: Mouse
Target Species: Human
Immunogen: Human NALM1 + NALM16 cells
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: SJ25C1
Applications: Flow Cytometry
Conjugate: APC-H7
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype: IgG1 κ
Purification Method: Affinity Purified
Antigen:
CD19
Concentration:
__
Classification:
Monoclonal
Host Species:
Mouse
Target Species:
Human
Immunogen:
Human NALM1 + NALM16 cells
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
SJ25C1
Applications:
Flow Cytometry
Conjugate:
APC-H7
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype:
IgG1 κ
Purification Method:
Affinity Purified
Antigen: CD19
Concentration: 0.2mg/mL
Classification: Monoclonal
Host Species: Rat
Target Species: Mouse
Immunogen: Mouse CD19 Transfected Cell Line
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: 1D3
Applications: Flow Cytometry
Conjugate: Violet Fluor 450 (V450)
Regulatory Status: RUO
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Isotype: IgG2a κ
Purification Method: Affinity Purified
Antigen:
CD19
Concentration:
0.2mg/mL
Classification:
Monoclonal
Host Species:
Rat
Target Species:
Mouse
Immunogen:
Mouse CD19 Transfected Cell Line
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
1D3
Applications:
Flow Cytometry
Conjugate:
Violet Fluor 450 (V450)
Regulatory Status:
RUO
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Isotype:
IgG2a κ
Purification Method:
Affinity Purified