3855832
Rb2 Mouse, Unlabeled, Clone: 10, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Rb2
Concentration
250μg/mL
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Cell Biology
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype
IgG2a
Purification Method
Affinity Purified
Clone
10
Applications
Western Blot
Conjugate
Unconjugated
Regulatory Status
RUO
Target Species
Chicken, Drosophila, Human, Mouse, Rat
Immunogen
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
Description
- The pRb2 protein shows a high degree of identity with pRb and the related p107 protein
- Both pRb and p107 bind to the adenovirus E1A, SV40 large T antigen, and papillomavirus E7 viral proteins
- This binding initiates the release of transcription factors which are required for the expression of cell cycle-regulated genes
- pRb, pRb2, and p107 interact with a conserved motif in these three viral proteins
- In the E1A protein, this area is known as transforming domain 2, which is required for growth activation
- The E1A-binding domain in pRb and p107 is a conserved motif known as the “pocket region” which consists of conserved A and B regions separated by non-conserved spacers of different sizes in pRb and p107
- It is the pocket regions of pRb and p107 that associate with the E2F transcription factor
- pRb2 also contains the conserved pocket region suggesting that it has functional similarities to pRb and p107
- Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting
Compare Similar Items
Show Difference
Antigen: Rb2
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG2a
Purification Method: Affinity Purified
Clone: 10
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Chicken, Drosophila, Human, Mouse, Rat
Immunogen: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Rb2
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG2a
Purification Method:
Affinity Purified
Clone:
10
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Chicken, Drosophila, Human, Mouse, Rat
Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: CD45
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Immunology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Clone: 69
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Human, Mouse, Rat
Immunogen: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
CD45
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Immunology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Clone:
69
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Human, Mouse, Rat
Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: p130 [Cas]
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Clone: 21
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Canine, Chicken, Human, Mouse, Rat
Immunogen: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
p130 [Cas]
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Clone:
21
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Canine, Chicken, Human, Mouse, Rat
Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: c-Cbl
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Clone: 17
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Canine, Chicken, Human, Mouse, Rat
Immunogen: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
c-Cbl
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Clone:
17
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Canine, Chicken, Human, Mouse, Rat
Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.