3855879

eNOS/NOS Type III Mouse, Unlabeled, Clone: 3, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

eNOS/NOS Type III

Concentration

250μg/mL

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cell Biology

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype

IgG1 κ

Purification Method

Affinity Purified

Clone

3

Applications

Western Blot

Conjugate

Unconjugated

Regulatory Status

RUO

Target Species

Human, Mouse, Rat

Immunogen

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

Description

  • Nitric oxide synthase (NOS), a cell-type specific enzyme, catalyzes the synthesis of nitric oxide (NO)
  • NO is a short-lived radical that transmits signals involved in vasorelaxation, neurotransmission, and cytotoxicity
  • In neurons and endothelial cells, constitutive NOS (cNOS) is activated by agonists that increase intracellular Ca 2 + levels and enhance calmodulin binding
  • Neuronal NOS (mNOS) and endothelial NOS (eNOS) have recognition sites for NADPH, FAD, FMN, and calmodulin and both are regulated in a similar manner
  • The human forms exhibit 52% amino acid identity
  • However, they are distinct gene products of about 155kDa (mNOS) and 140kDa (eNOS)
  • The eNOS gene was cloned from human vascular endothelium as well as from bovine aortic endothelial cells (BAEC)
  • eNOS protein has a unique N-myristylation consensus sequence that may explain its membrane localization
  • Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

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Fischer Scientific

3855879

Mouse Monoclonal Antibody...


Antigen:
eNOS/NOS Type III

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Clone:
3

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat

Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

Img

Fischer Scientific

3855893

Mouse Monoclonal Antibody...


Antigen:
nNOS

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG2a

Purification Method:
Affinity Purified

Clone:
16

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Canine, Human, Mouse, Rat

Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

Img

Fischer Scientific

3855893

Mouse Monoclonal Antibody...


Antigen:
nNOS

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG2a

Purification Method:
Affinity Purified

Clone:
16

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Canine, Human, Mouse, Rat

Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

Img

Fischer Scientific

3855920

Mouse Monoclonal Antibody...


Antigen:
Ran

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG2a

Purification Method:
Affinity Purified

Clone:
20

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Canine, Chicken, Human, Mouse, Rat

Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.