3968334

CD117 Mouse anti-Human, APC, Clone: YB5.B8, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD117

Concentration

0.2mg/mL

Classification

Monoclonal

Host Species

Mouse

Target Species

Human

Immunogen

Acute myelocytic leukemia blasts

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone

YB5.B8

Applications

Flow Cytometry

Conjugate

APC

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype

IgG1 κ

Purification Method

Affinity Purified

Description

KIT; c-Kit; SCFR; PBT; Mast/stem cell growth factor receptor

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Description

  • Recognizes CD117 (the C-Kit), a 145kDa cell-surface glycoprotein with tyrosine kinase activity
  • CD117 is present on hematopoietic progenitor cell subsets, thymocytes, mast cells, hepatocytes and histiocytes
  • CD117 serves as a cytokine receptor for steel factor (SLF), also known as stem cell factor (SCF) or mast cell growth factor (MGF)
  • The interaction of c-kit and SLF is crucial to hematopoiesis, mast cell differentiation, melanogenesis, and germ cell development
  • The ability of YB5.B8 antibody to block the binding of c-kit ligand is still controversial
  • This antibody is routinely tested by flow cytometric analysis
  • Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature
  • Host Species: Mouse Clone: YB5.B8 Isotype: IgG1 κ Species Reactivity: Human Flow Cytometry

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Img

Fischer Scientific

3968334

Mouse Monoclonal Antibody...


Antigen:
CD117

Concentration:
0.2mg/mL

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Acute myelocytic leukemia blasts

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
YB5.B8

Applications:
Flow Cytometry

Conjugate:
APC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
KIT; c-Kit; SCFR; PBT; Mast/stem cell growth factor receptor

Img

Fischer Scientific

3968377

Mouse Monoclonal Antibody...


Antigen:
ALDH

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Human ALDH1 aa. 7-128

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

Clone:
44

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1

Purification Method:
Affinity Purified

Description:
__

Img

Fischer Scientific

3968377

Mouse Monoclonal Antibody...


Antigen:
ALDH

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Human ALDH1 aa. 7-128

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

Clone:
44

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1

Purification Method:
Affinity Purified

Description:
__

Img

Fischer Scientific

3968377

Mouse Monoclonal Antibody...


Antigen:
ALDH

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Human ALDH1 aa. 7-128

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

Clone:
44

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1

Purification Method:
Affinity Purified

Description:
__