3968529

CD106 Rat anti-Mouse, FITC, Clone: 429 (MVCAM.A), BD

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD106

Concentration

0.5mg/mL

Classification

Monoclonal

Host Species

Rat

Research Discipline

Immunology

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype

IgG2a κ

Purification Method

Affinity Purified

Description

Vcam-1; Vascular cell adhesion molecule 1; Vascular cell adhesion protein 1

Clone

429 (MVCAM.A)

Applications

Flow Cytometry

Conjugate

FITC

Regulatory Status

RUO

Target Species

Mouse

Immunogen

Mouse preadipose cell line PA6

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • The 429 monoclonal antibody specifically binds to both the long (∼110 kDa) transmembrane-spanning form and the truncated (∼47 kDa) GPI-linked form of vascular cell adhesion molecule-1 (VCAM-1, CD106)
  • CD106 is constitutively expressed on bone marrow stromal cells, myeloid cells, and splenic dendritic cells
  • Its expression on endothelial cells is upregulated by inflammatory cytokines and in certain pathologic conditions
  • CD106 expression has also been detected on apoptotic thymocytes, splenocytes, and lymphoid cell lines
  • VCAM-1 is a counter-receptor for VLA-4 ( α;4 β; 1 integrin) and LPAM-1 ( α;4 β; 7 integrin), and the 429 antibody partially blocks VCAM-1-mediated binding functions
  • Source of the immunogen was the mouse preadipose cell line PA6.

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3968529

Rat Monoclonal Antibody...


Antigen:
CD106

Concentration:
0.5mg/mL

Classification:
Monoclonal

Host Species:
Rat

Research Discipline:
Immunology

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Description:
Vcam-1; Vascular cell adhesion molecule 1; Vascular cell adhesion protein 1

Clone:
429 (MVCAM.A)

Applications:
Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Target Species:
Mouse

Immunogen:
Mouse preadipose cell line PA6

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Mouse Monoclonal Antibody...


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Concentration:
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Classification:
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Host Species:
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Research Discipline:
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Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Flow Cytometry

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