3968542

CD107a Mouse anti-Human, FITC, Clone: H4A3, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD107a

Applications

Flow Cytometry

Conjugate

FITC

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype

IgG1 κ

Purification Method

Affinity Purified

Description

LAMP1; LAMP-1; LAMPA; LGP120

Clone

H4A3

Classification

Monoclonal

Host Species

Mouse

Target Species

Human

Immunogen

Human Adult Adherent Peripheral Blood Cells

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • Reacts with the heavily glycosylated 110kDa lysosomal-associated membrane protein, LAMP-1
  • LAMP-1 is a widely expressed intracellular antigen
  • It is also expressed on the surface of activated platelets, PHA-activated lymphocytes and some tumor cell lines, including U937 and KG1a
  • LAMP-1 has been shown to be a ligand for E-selectin-mediated cell adhesion
  • LAMP-1 and LAMP-2 (CD107b) are carriers for poly-N-acetyllactosamines, and are able to display sialyl Le[x] termini
  • This antibody is routinely tested by flow cytometric analysis
  • Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature
  • Host Species: Mouse Clone: H4A3 Isotype: IgG1 κ Species Reactivity: Human Intracellular Staining

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