3968884

CD154 Mouse anti-Human, APC, Clone: TRAP1, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD154

Applications

Flow Cytometry

Conjugate

APC

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone

TRAP1

Classification

Monoclonal

Host Species

Mouse

Target Species

Baboon, Cynomolgus, Human, Rhesus Monkey

Isotype

IgG1 κ

Purification Method

Affinity Purified

Description

CD40LG; CD40 ligand; CD40L; TNFSF5; T-BAM; TRAP

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Description

  • Reacts with CD40 ligand (CD40L), a 39kDa type II membrane glycoprotein expressed on activated T cells
  • CD40-CD40L interaction plays a very important role in T cell-dependent B-cell proliferation, differentiation, and memory cell formation
  • Anti-CD40L mAb partially blocks T cell-B cell interaction affecting subsequent proliferation, differentiation, and memory cell formation
  • Anti-CD40L mAb partially blocks T cell-B cell interaction affecting subsequent proliferation, IL-2R expression and differentiation of B cells
  • In addition, blocking of CD40-CD40L interaction has been demonstrated with soluble CD40, resulting in the inhibition of immunoglobulin isotype switching
  • It has been reported that patients with X-linked hyper-IgM syndrome have defective expression of functional CD40L due to a defective gene that encodes CD40L
  • This antibody is routinely tested by flow cytometric analysis
  • Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature
  • Host Species: Mouse Clone: TRAP1 Isotype: IgG1 κ Species Reactivity: Human Flow Cytometry

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3968884

Mouse Monoclonal Antibody...


Antigen:
CD154

Applications:
Flow Cytometry

Conjugate:
APC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
TRAP1

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
CD40LG; CD40 ligand; CD40L; TNFSF5; T-BAM; TRAP

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Antigen:
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Applications:
Flow Cytometry

Conjugate:
Violet Fluor 450 (V450)

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
3G8

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
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Antigen:
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Applications:
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Conjugate:
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Regulatory Status:
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Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
2.4G2

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Isotype:
IgG2b κ

Purification Method:
Affinity Purified

Description:
FcγRIII/FcγRII; Fcgr3/Fcgr2

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Antigen:
CD4

Applications:
Flow Cytometry

Conjugate:
Biotin

Regulatory Status:
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Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone:
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Classification:
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Host Species:
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Target Species:
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Isotype:
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Purification Method:
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