3968957
CD4 Rat anti-Mouse, Biotin, Clone: H129.19, BD
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD4
Concentration
0.5mg/mL
Classification
Monoclonal
Host Species
Rat
Research Discipline
Immunology
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype
IgG2a κ
Purification Method
Affinity Purified
Description
L3T4
Clone
H129.19
Applications
Flow Cytometry
Conjugate
Biotin
Regulatory Status
RUO
Target Species
Mouse
Immunogen
A.TH mouse CTL clone A15.1.17
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Description
- The H129.19 antibody reacts with the CD4 (L3T4) differentiation antigen expressed on thymocytes, a subpopulation of mature T lymphocytes (i.e., MHC class II-restricted T cells, including most T helper cells), and a subset of NK-T cells of all mouse strains tested
- CD4 has also been detected on pluirpotent hematopoietic stem cells, bone marrow myeloid precursors, intrathymic lymphoid precursors, and a subset of splenic dendritic cells
- CD4 is expressed on the plasma membrane of mouse egg cells and is involved in adhesion of the egg to MHC class II-bearing sperm
- CD4 is an antigen coreceptor on the T-cell surface which interacts with MHC class II molecules on antigen-presenting cells
- It participates in T-cell activation through its association with the T-cell receptor complex and protein tyrosine lck
- H129.19 mAb blocks binding of the anti-mouse CD4 mAbs Gk1.5 (Cat
- No
- 557307/553729) and RM4-5 (Cat
- No
- 553046/553047), but not RM4-4 (Cat
- No
- 553055) antibody
- mAb H129.19 inhibits various responses of T helper cells to antigenic or mitogenic stimuli
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature
- Host Species: Rat Clone: H129.19 Isotype: IgG2a κ Species Reactivity: Mouse Immunogen: A.TH mouse CTL clone A15.1.17 Flow Cytometry
Compare Similar Items
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Antigen: CD4
Concentration: 0.5mg/mL
Classification: Monoclonal
Host Species: Rat
Research Discipline: Immunology
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG2a κ
Purification Method: Affinity Purified
Description: L3T4
Clone: H129.19
Applications: Flow Cytometry
Conjugate: Biotin
Regulatory Status: RUO
Target Species: Mouse
Immunogen: A.TH mouse CTL clone A15.1.17
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD4
Concentration:
0.5mg/mL
Classification:
Monoclonal
Host Species:
Rat
Research Discipline:
Immunology
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG2a κ
Purification Method:
Affinity Purified
Description:
L3T4
Clone:
H129.19
Applications:
Flow Cytometry
Conjugate:
Biotin
Regulatory Status:
RUO
Target Species:
Mouse
Immunogen:
A.TH mouse CTL clone A15.1.17
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD4
Concentration: 0.5mg/mL
Classification: Monoclonal
Host Species: Rat
Research Discipline: Immunology
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG2a κ
Purification Method: Affinity Purified
Description: Cd4; CD4 antigen; L3T4; Ly-4; T-cell surface antigen T4/Leu-3
Clone: RM4-5
Applications: Flow Cytometry
Conjugate: Biotin
Regulatory Status: RUO
Target Species: Mouse
Immunogen: Mouse Thymocytes (BALB/c)
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD4
Concentration:
0.5mg/mL
Classification:
Monoclonal
Host Species:
Rat
Research Discipline:
Immunology
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG2a κ
Purification Method:
Affinity Purified
Description:
Cd4; CD4 antigen; L3T4; Ly-4; T-cell surface antigen T4/Leu-3
Clone:
RM4-5
Applications:
Flow Cytometry
Conjugate:
Biotin
Regulatory Status:
RUO
Target Species:
Mouse
Immunogen:
Mouse Thymocytes (BALB/c)
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD184
Concentration: __
Classification: Monoclonal
Host Species: Mouse
Research Discipline: __
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype: IgG2a κ
Purification Method: Affinity Purified
Description: CXCR4; Fusin; SDF-1 receptor; LAP3; LCR1; LESTR; NPYY3R; NPY3R; WHIM; HM89
Clone: 12G5
Applications: Flow Cytometry
Conjugate: APC
Regulatory Status: RUO
Target Species: Human
Immunogen: SIVmac variant CP-MAC-infected Sup-T1 cells
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD184
Concentration:
__
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
__
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype:
IgG2a κ
Purification Method:
Affinity Purified
Description:
CXCR4; Fusin; SDF-1 receptor; LAP3; LCR1; LESTR; NPYY3R; NPY3R; WHIM; HM89
Clone:
12G5
Applications:
Flow Cytometry
Conjugate:
APC
Regulatory Status:
RUO
Target Species:
Human
Immunogen:
SIVmac variant CP-MAC-infected Sup-T1 cells
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD184
Concentration: 0.5mg/mL
Classification: Monoclonal
Host Species: Rat
Research Discipline: __
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG2b κ
Purification Method: Affinity Purified
Description: CXCR4, C-X-C chemokine receptor type 4; Fusin; LESTR; PB-CKR; Sdf1r
Clone: 2B11/CXCR4
Applications: Flow Cytometry
Conjugate: FITC
Regulatory Status: RUO
Target Species: Mouse
Immunogen: GST-NCXCR4 fusion protein
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD184
Concentration:
0.5mg/mL
Classification:
Monoclonal
Host Species:
Rat
Research Discipline:
__
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG2b κ
Purification Method:
Affinity Purified
Description:
CXCR4, C-X-C chemokine receptor type 4; Fusin; LESTR; PB-CKR; Sdf1r
Clone:
2B11/CXCR4
Applications:
Flow Cytometry
Conjugate:
FITC
Regulatory Status:
RUO
Target Species:
Mouse
Immunogen:
GST-NCXCR4 fusion protein
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.