3969070

CD184 Mouse anti-Human, APC, Clone: 12G5, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD184

Applications

Flow Cytometry

Conjugate

APC

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype

IgG2a κ

Purification Method

Affinity Purified

Description

CXCR4; Fusin; SDF-1 receptor; LAP3; LCR1; LESTR; NPYY3R; NPY3R; WHIM; HM89

Clone

12G5

Classification

Monoclonal

Host Species

Mouse

Target Species

Human

Immunogen

SIVmac variant CP-MAC-infected Sup-T1 cells

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • Reacts with fusin (CXCR4), a seven-transmembrane domain, G-protein-linked glycoprotein
  • Fusin is expressed on a wide variety of CD4+ and CD4- cells including those from spleen, brain and lung
  • It has been shown to function as a cofactor for infection with T-cell tropic strains of HIV-1 and also as a receptor for CD4-independent infection
  • 12G5 antibody has been reported to block CD4-independent infection by HIV-2 and CD4-dependent infection by some T-cell tropic isolates of HIV-1
  • Host Species: Mouse Clone: 12G5 Isotype: IgG2a κ Species Reactivity: Human Flow Cytometry

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Fischer Scientific

3969070

Mouse Monoclonal Antibody...


Antigen:
CD184

Applications:
Flow Cytometry

Conjugate:
APC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Description:
CXCR4; Fusin; SDF-1 receptor; LAP3; LCR1; LESTR; NPYY3R; NPY3R; WHIM; HM89

Clone:
12G5

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
SIVmac variant CP-MAC-infected Sup-T1 cells

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Rat Monoclonal Antibody...


Antigen:
CD184

Applications:
Flow Cytometry

Conjugate:
FITC

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2b κ

Purification Method:
Affinity Purified

Description:
CXCR4, C-X-C chemokine receptor type 4; Fusin; LESTR; PB-CKR; Sdf1r

Clone:
2B11/CXCR4

Classification:
Monoclonal

Host Species:
Rat

Target Species:
Mouse

Immunogen:
GST-NCXCR4 fusion protein

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Applications:
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Isotype:
IgG2a κ

Purification Method:
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Clone:
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Classification:
Monoclonal

Host Species:
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Target Species:
Mouse

Immunogen:
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Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Antigen:
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Applications:
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Formulation:
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Isotype:
IgG2a κ

Purification Method:
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Description:
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Clone:
1D3

Classification:
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Host Species:
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Target Species:
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Immunogen:
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Primary or Secondary:
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Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.