3968959
CD4 Rat anti-Mouse, Biotin, Clone: RM4-5, BD
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD4
Concentration
0.5mg/mL
Classification
Monoclonal
Host Species
Rat
Research Discipline
Immunology
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype
IgG2a κ
Purification Method
Affinity Purified
Description
Cd4; CD4 antigen; L3T4; Ly-4; T-cell surface antigen T4/Leu-3
Clone
RM4-5
Applications
Flow Cytometry
Conjugate
Biotin
Regulatory Status
RUO
Target Species
Mouse
Immunogen
Mouse Thymocytes (BALB/c)
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Description
- The RM4-5 clone has been reported to react with the CD4 (L3T4) differentiation antigen expressed on most thymocytes, subpopulations of mature T lymphocytes (i.e., MHC class II-restricted T cells, including most T helper cells and immunosuppressive regulatory T cells), and a subset of NK-T cells
- CD4 has also been reported to be detected on pluripotent hematopoietic stem cells, bone marrow myeloid and B-lymphocyte precursors, intrathymic lymphoid precursors, and a subset of splenic dendritic cells
- CD4 has been reported to be expressed on the plasma membrane of mouse egg cells and is involved in adhesion of the egg to MHC class II-bearing sperm
- CD4 is an antigen coreceptor on the T-cell surface which interacts with MHC class II molecules on antigen-presenting cells
- It participates in T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase lck
- Purified RM4-5 mAb has been reported to block the binding of FITC-conjugated anti-mouse CD4 clones GK1.5 and H129.19, but not the RM4-4 clone
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature
- Host Species: Rat Clone: RM4-5 Isotype: IgG2a κ Species Reactivity: Mouse Immunogen: Mouse Thymocytes (BALB/c) Cell Separation, Flow Cytometry
Compare Similar Items
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Antigen: CD4
Concentration: 0.5mg/mL
Classification: Monoclonal
Host Species: Rat
Research Discipline: Immunology
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG2a κ
Purification Method: Affinity Purified
Description: Cd4; CD4 antigen; L3T4; Ly-4; T-cell surface antigen T4/Leu-3
Clone: RM4-5
Applications: Flow Cytometry
Conjugate: Biotin
Regulatory Status: RUO
Target Species: Mouse
Immunogen: Mouse Thymocytes (BALB/c)
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD4
Concentration:
0.5mg/mL
Classification:
Monoclonal
Host Species:
Rat
Research Discipline:
Immunology
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG2a κ
Purification Method:
Affinity Purified
Description:
Cd4; CD4 antigen; L3T4; Ly-4; T-cell surface antigen T4/Leu-3
Clone:
RM4-5
Applications:
Flow Cytometry
Conjugate:
Biotin
Regulatory Status:
RUO
Target Species:
Mouse
Immunogen:
Mouse Thymocytes (BALB/c)
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD184
Concentration: __
Classification: Monoclonal
Host Species: Mouse
Research Discipline: __
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype: IgG2a κ
Purification Method: Affinity Purified
Description: CXCR4; Fusin; SDF-1 receptor; LAP3; LCR1; LESTR; NPYY3R; NPY3R; WHIM; HM89
Clone: 12G5
Applications: Flow Cytometry
Conjugate: APC
Regulatory Status: RUO
Target Species: Human
Immunogen: SIVmac variant CP-MAC-infected Sup-T1 cells
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD184
Concentration:
__
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
__
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype:
IgG2a κ
Purification Method:
Affinity Purified
Description:
CXCR4; Fusin; SDF-1 receptor; LAP3; LCR1; LESTR; NPYY3R; NPY3R; WHIM; HM89
Clone:
12G5
Applications:
Flow Cytometry
Conjugate:
APC
Regulatory Status:
RUO
Target Species:
Human
Immunogen:
SIVmac variant CP-MAC-infected Sup-T1 cells
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD184
Concentration: 0.5mg/mL
Classification: Monoclonal
Host Species: Rat
Research Discipline: __
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG2b κ
Purification Method: Affinity Purified
Description: CXCR4, C-X-C chemokine receptor type 4; Fusin; LESTR; PB-CKR; Sdf1r
Clone: 2B11/CXCR4
Applications: Flow Cytometry
Conjugate: FITC
Regulatory Status: RUO
Target Species: Mouse
Immunogen: GST-NCXCR4 fusion protein
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD184
Concentration:
0.5mg/mL
Classification:
Monoclonal
Host Species:
Rat
Research Discipline:
__
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG2b κ
Purification Method:
Affinity Purified
Description:
CXCR4, C-X-C chemokine receptor type 4; Fusin; LESTR; PB-CKR; Sdf1r
Clone:
2B11/CXCR4
Applications:
Flow Cytometry
Conjugate:
FITC
Regulatory Status:
RUO
Target Species:
Mouse
Immunogen:
GST-NCXCR4 fusion protein
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: CD19
Concentration: 0.2mg/mL
Classification: Monoclonal
Host Species: Rat
Research Discipline: __
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG2a κ
Purification Method: Affinity Purified
Description: __
Clone: 1D3
Applications: Flow Cytometry
Conjugate: APC
Regulatory Status: RUO
Target Species: Mouse
Immunogen: Mouse CD19 Transfected Cell Line
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
CD19
Concentration:
0.2mg/mL
Classification:
Monoclonal
Host Species:
Rat
Research Discipline:
__
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG2a κ
Purification Method:
Affinity Purified
Description:
__
Clone:
1D3
Applications:
Flow Cytometry
Conjugate:
APC
Regulatory Status:
RUO
Target Species:
Mouse
Immunogen:
Mouse CD19 Transfected Cell Line
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.