3970509
Cyclin B1 Mouse, Unlabeled, Clone: GNS-1, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Cyclin B1
Concentration
0.5mg/mL
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Cell Biology
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype
IgG1
Purification Method
Affinity Purified
Clone
GNS-1
Applications
Western Blot
Conjugate
Unconjugated
Regulatory Status
RUO
Target Species
Hamster, Human, Mouse
Immunogen
Human Cyclin B1 Recombinant Protein
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
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Description
- Cyclins and cyclin-dependent kinases (cdks) are evolutionarily conserved proteins that are essential for cell-cycle control in eukaryotes
- Cyclins (regulatory subunits) bind to cdks (catlytic subunits) to form complexes that regulate the progression of the cell cycle
- The main cyclin-cdks complexes formed in vertebrate cells are cyclin D-cdk4 (G0/G1), cyclin E-cdk2 (G1/S), cyclin A-cdk2 (S) and cyclin B1-cdk1 (G2/M)
- These complexes are regulated by activating and inhibitory phosphorylation events, as well as by interactions with small regulatory proteins, such as p21 and p27 [Kip1]
- Cyclin B1 is a mitotic cyclin, where expression is normally low in G0/G1, increases in S and is maximal during the G2/M phase
- Cyclin B1 is rapidly degraded at the end of mitosis, and is required for cells to exit from mitosis
- This antibody has been reported to react to hamster and mouse cyclin B1
- In addition, the GNS-1 antibody has been reported to recognize an epitope between amino acids 1-21 of human cyclin B1
- Host Species: Mouse Clone: GNS-1 Isotype: IgG1 Species Reactivity: Human Immunogen: Human Cyclin B1 Recombinant Protein Formula Weight [Chemical]: 62kDa Bioimaging, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blotting
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Antigen: Cyclin B1
Concentration: 0.5mg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Clone: GNS-1
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Hamster, Human, Mouse
Immunogen: Human Cyclin B1 Recombinant Protein
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
Cyclin B1
Concentration:
0.5mg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Clone:
GNS-1
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Hamster, Human, Mouse
Immunogen:
Human Cyclin B1 Recombinant Protein
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: Cyclin B1
Concentration: 0.5mg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG2a
Purification Method: Affinity Purified
Clone: GNS-11
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Human, Mouse
Immunogen: Recombinant Human Cyclin B1
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
Cyclin B1
Concentration:
0.5mg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG2a
Purification Method:
Affinity Purified
Clone:
GNS-11
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Human, Mouse
Immunogen:
Recombinant Human Cyclin B1
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: Cyclin B1
Concentration: 0.5mg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG2a
Purification Method: Affinity Purified
Clone: GNS-11
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Human, Mouse
Immunogen: Recombinant Human Cyclin B1
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
Cyclin B1
Concentration:
0.5mg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG2a
Purification Method:
Affinity Purified
Clone:
GNS-11
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Human, Mouse
Immunogen:
Recombinant Human Cyclin B1
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Antigen: Cyclin D1
Concentration: 0.5mg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Clone: G124-326
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Human, Mouse
Immunogen: Recombinant full-length human cyclin D1
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Antigen:
Cyclin D1
Concentration:
0.5mg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Clone:
G124-326
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Human, Mouse
Immunogen:
Recombinant full-length human cyclin D1
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C