3970657
Foxp3 Rat anti-Mouse, Alexa Fluor 647, Clone: MF23, BD
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Foxp3
Concentration
0.2mg/mL
Classification
Monoclonal
Host Species
Rat
Research Discipline
Immunology
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype
IgG2b
Purification Method
Affinity Purified
Description
Forkhead box p3; Forkhead box protein p3; JM2; Scurfin; Scurfy; Sf
Clone
MF23
Applications
Flow Cytometry
Conjugate
Alexa Fluor 647
Regulatory Status
RUO
Target Species
Mouse
Immunogen
Mouse Foxp3 Recombinant Protein
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- Foxp3 is a 50-55kDa protein also known as Forkhead box P3, JM2, or IPEX
- It is a member of the forkhead or winged helix family of transcription factors and is specifically expressed by T regulatory (Treg) cells
- Foxp3 has been reported to be a key regulatory protein for Treg cell development and function
- Ectopic expression of Foxp3 in conventional T cells is sufficient to induce suppressive activity, repress the production of cytokines such as IL2 and IFN-γ, and upregulate Treg cell-associated molecules such as CD25, CTLA4 and GITR
- It has been found that the mutation of Foxp3 is responsible for “scurfy” mice
- When overexpressed, Foxp3 leads to poor T cell proliferation and activation
- Monoclonal antibody MF23 reacts with mouse Foxp3
- Immunoblotting with MF23 antibody has confirmed it recognizes an epitope between 1-87 amino acids in the N-terminal domain
- Host Species: Rat Clone: MF23 Isotype: IgG2b Species Reactivity: Mouse Immunogen: Mouse Foxp3 Recombinant Protein Intracellular Staining
Compare Similar Items
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Antigen: Foxp3
Concentration: 0.2mg/mL
Classification: Monoclonal
Host Species: Rat
Research Discipline: Immunology
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG2b
Purification Method: Affinity Purified
Description: Forkhead box p3; Forkhead box protein p3; JM2; Scurfin; Scurfy; Sf
Clone: MF23
Applications: Flow Cytometry
Conjugate: Alexa Fluor 647
Regulatory Status: RUO
Target Species: Mouse
Immunogen: Mouse Foxp3 Recombinant Protein
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Foxp3
Concentration:
0.2mg/mL
Classification:
Monoclonal
Host Species:
Rat
Research Discipline:
Immunology
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG2b
Purification Method:
Affinity Purified
Description:
Forkhead box p3; Forkhead box protein p3; JM2; Scurfin; Scurfy; Sf
Clone:
MF23
Applications:
Flow Cytometry
Conjugate:
Alexa Fluor 647
Regulatory Status:
RUO
Target Species:
Mouse
Immunogen:
Mouse Foxp3 Recombinant Protein
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: FoxP3
Concentration: __
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Immunology
Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Description: Scurfin, IPEX, JM2
Clone: 259D/C7
Applications: Flow Cytometry
Conjugate: Violet Fluor 450 (V450)
Regulatory Status: RUO
Target Species: Baboon, Cynomolgus, Human, Rhesus Monkey
Immunogen: FoxP3 recombinant protein
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
FoxP3
Concentration:
__
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Immunology
Formulation:
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Description:
Scurfin, IPEX, JM2
Clone:
259D/C7
Applications:
Flow Cytometry
Conjugate:
Violet Fluor 450 (V450)
Regulatory Status:
RUO
Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey
Immunogen:
FoxP3 recombinant protein
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: Foxp3
Concentration: 0.2mg/mL
Classification: Monoclonal
Host Species: Rat
Research Discipline: Immunology
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG2b
Purification Method: Affinity Purified
Description: __
Clone: MF23
Applications: Flow Cytometry
Conjugate: PE
Regulatory Status: RUO
Target Species: Mouse
Immunogen: Mouse Foxp3 Recombinant Protein
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Foxp3
Concentration:
0.2mg/mL
Classification:
Monoclonal
Host Species:
Rat
Research Discipline:
Immunology
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG2b
Purification Method:
Affinity Purified
Description:
__
Clone:
MF23
Applications:
Flow Cytometry
Conjugate:
PE
Regulatory Status:
RUO
Target Species:
Mouse
Immunogen:
Mouse Foxp3 Recombinant Protein
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen: Foxp3
Concentration: 0.2mg/mL
Classification: Monoclonal
Host Species: Rat
Research Discipline: Immunology
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype: IgG2b
Purification Method: Affinity Purified
Description: __
Clone: MF23
Applications: Flow Cytometry
Conjugate: PE
Regulatory Status: RUO
Target Species: Mouse
Immunogen: Mouse Foxp3 Recombinant Protein
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Antigen:
Foxp3
Concentration:
0.2mg/mL
Classification:
Monoclonal
Host Species:
Rat
Research Discipline:
Immunology
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype:
IgG2b
Purification Method:
Affinity Purified
Description:
__
Clone:
MF23
Applications:
Flow Cytometry
Conjugate:
PE
Regulatory Status:
RUO
Target Species:
Mouse
Immunogen:
Mouse Foxp3 Recombinant Protein
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.