40-410-7942

CD107a (LAMP-1) Monoclonal Antibody (eBioH4A3), Brilliant Violet™ 421, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 40-410-7942-Each-of-1 In Stock ₹ 30,716.04

40-410-7942 - Each of 1

₹ 30,716.04

In Stock

Quantity

1

Base Price: ₹ 30,716.04

GST (18%): ₹ 5,528.887

Total Price: ₹ 36,244.927

Antigen

CD107a (LAMP-1)

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P11279

Gene Symbols

LAMP1

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3916

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

eBioH4A3

Conjugate

Brilliant Violet 421

Gene

LAMP1

Gene Alias

120 kDa lysosomal membrane glycoprotein; AI196048; CD107 antigen-like family member A; CD107a; I79_011073; Lamp I; LAMP1; LAMP-1; LAMPA; LGP120; LGP-120; LGPA; LGP-A; lysosomal associated membrane protein 1; Lysosomal associated membrane protein 1 (120 kDa); lysosomal membrane glycoprotein 1; lysosomal membrane glycoprotein A; lysosomal-associated membrane protein 1; lysosome-associated membrane glycoprotein 1; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 PRECURSOR (LAMP-1) (LGP-A) (LGP-120) (CD107A) (P2B); lysosome-associated membrane protein 1; P2B

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • LAMP1 (CD107a, lysosome-associated membrane protein-1) together with LAMP-2, is a major constituent of lysosomal membrane, 1-2% of total CD107a is found also on the plasma membrane
  • LAMP1 is a heavily glycosylated membrane protein which contains a putative signal peptide, 18 sites for N-linked glycosylation, a single membrane-spanning segment and a short (11 amino acid) cytosolic tail
  • The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes
  • LAMP1 is a type 1 integral membrane protein that is transported from trans-Golgi network to endosomes and then lysosomes
  • Upon cell activation, LAMP1 transfer to the plasma membrane is dependent on a carboyxl-terminal tyrosine based motif (YXXI)
  • Perturbation in the spacing between the tyrosine based motif relative to the membrane abolishes lysosome localization of LAMP1, and this mutant protein then cycles between the plasma membrane and the endosome
  • Cell surface LAMP1 (and LAMP2) have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, therefore, they are possibly involved in the adhesion of PBMC to the site of inflammation
  • Increased LAMP1 immunoreactivity is observed in neurons and glial cells surrounding senile plaques in Alzheimer’s Disease (AD) cases, and is localized in medullary epithelial cells, single macrophages and lymphocytes in acute thymic involution
  • LAMP1 is a good marker of mast cell activation.

Compare Similar Items

Show Difference

Img

Fischer Scientific

40-410-7942

--


Antigen:
CD107a (LAMP-1)

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P11279

Gene Symbols:
LAMP1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3916

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
eBioH4A3

Conjugate:
Brilliant Violet 421

Gene:
LAMP1

Gene Alias:
120 kDa lysosomal membrane glycoprotein; AI196048; CD107 antigen-like family member A; CD107a; I79_011073; Lamp I; LAMP1; LAMP-1; LAMPA; LGP120; LGP-120; LGPA; LGP-A; lysosomal associated membrane protein 1; Lysosomal associated membrane protein 1 (120 kDa); lysosomal membrane glycoprotein 1; lysosomal membrane glycoprotein A; lysosomal-associated membrane protein 1; lysosome-associated membrane glycoprotein 1; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 PRECURSOR (LAMP-1) (LGP-A) (LGP-120) (CD107A) (P2B); lysosome-associated membrane protein 1; P2B

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Fischer Scientific

40-411-7180

--


Antigen:
CD117 (c-Kit)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
P05532, Q2HWD6

Gene Symbols:
KIT

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16590, 396810

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
2B8

Conjugate:
Brilliant Violet 421

Gene:
KIT

Gene Alias:
belly-spot, Bs, CD117, ckit, C-Kit, c-KIT gene1, c-kit protein, c-kit proto-oncogene protein, c-kit receptor, c-kit receptor tyrosine kinase, dominant spotting, Dominant white spotting, Fdc, Gsfsco1, Gsfsco5, Gsfsow3, KIT, kit oncogene, KIT proto-oncogene receptor tyrosine kinase, KIT proto-oncogene, receptor tyrosine kinase, mast cell growth factor receptor, mast/stem cell growth factor receptor, mast/stem cell growth factor receptor Kit, MGF, p145 c-kit, PBT, Piebald trait protein, protein kinase, proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, receptor tyrosine kinase c-kit, receptor tyrosine kinase type III, SCFR, SCO1, SCO5, Sl, soluble KIT variant 1, SOW3, spotted sterile male, Ssm, Steel Factor Receptor, Tr-kit, tyrosine kinase receptor, tyrosine kinase receptor c-KIT, tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein, W

Host Species:
Rat

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Porcine

Product Type:
__

Isotype:
IgG2b κ

Img

Fischer Scientific

40-411-7182

--


Antigen:
CD117 (c-Kit)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
P05532, Q2HWD6

Gene Symbols:
KIT

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16590, 396810

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
2B8

Conjugate:
Brilliant Violet 421

Gene:
KIT

Gene Alias:
belly-spot, Bs, CD117, ckit, C-Kit, c-KIT gene1, c-kit protein, c-kit proto-oncogene protein, c-kit receptor, c-kit receptor tyrosine kinase, dominant spotting, Dominant white spotting, Fdc, Gsfsco1, Gsfsco5, Gsfsow3, KIT, kit oncogene, KIT proto-oncogene receptor tyrosine kinase, KIT proto-oncogene, receptor tyrosine kinase, mast cell growth factor receptor, mast/stem cell growth factor receptor, mast/stem cell growth factor receptor Kit, MGF, p145 c-kit, PBT, Piebald trait protein, protein kinase, proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, receptor tyrosine kinase c-kit, receptor tyrosine kinase type III, SCFR, SCO1, SCO5, Sl, soluble KIT variant 1, SOW3, spotted sterile male, Ssm, Steel Factor Receptor, Tr-kit, tyrosine kinase receptor, tyrosine kinase receptor c-KIT, tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein, W

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Porcine

Product Type:
__

Isotype:
IgG2b κ

Img

Fischer Scientific

40-412-7180

--


Antigen:
CD127

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P16872

Gene Symbols:
Il7r

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16197

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
A7R34

Conjugate:
Brilliant Violet 421

Gene:
Il7r

Gene Alias:
CD127; CD127 antigen; CDW127; IL 7 receptor; IL 7R a; IL 7R subunit alpha; IL 7R a; IL 7Ra; IL 7Ra; IL7 receptor; IL-7 receptor alpha chain; IL7 receptor subunit alpha; IL-7 receptor subunit alpha; IL7R; IL-7R; IL7R a; IL7R alpha; IL7R subunit alpha; IL-7R subunit alpha; IL7R a; IL7RA; IL-7RA; IL-7Ralpha; IL-7R-alpha; IL7Ra; ILRA; interleukin 7 receptor; interleukin 7 receptor alpha chain; interleukin 7 receptor isoform H5-6; Interleukin7 receptor subunit alpha; interleukin-7 receptor subunit alpha; MGC107557; sCD127; soluble IL 7 receptor; soluble IL 7R

Host Species:
Rat

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
__

Isotype:
IgG2a κ