40-420-6942
CD206 (MMR) Monoclonal Antibody (19.2), Brilliant Violet™ 421, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 40-420-6942-Each-of-1 | In Stock | ₹ 30,716.04 |
40-420-6942 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,716.04
GST (18%): ₹ 5,528.887
Total Price: ₹ 36,244.927
Antigen
CD206 (MMR)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P22897
Gene Symbols
Mrc1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4360
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
19.2
Conjugate
Brilliant Violet 421
Gene
Mrc1
Gene Alias
AW259686; bA541I19.1; CD206; CELE_Y39A3CR.4; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; ddp-1; hMR; Human mannose receptor; macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; Mitochondrial import inner membrane translocase subunit Tim8; MMR; MR; MRC1; MRC1L1; tim-8; Y39A3CR.4
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Related Products
Description
- CD206 (MSR, Mannose receptor, MRC1) is a 175 kDa transmembrane protein belonging to the group of pattern recognition receptors
- CD206 is predominantly expressed in tissue macrophages, dendritic cells, a subpopulation of endothelial cells and sperm cells
- CD206 is thought to play a role in the innate and adaptive immune response
- CD206 is also expressed on microglia and mato cells of the brain but not astrocytes or neurons
- CD206 also mediate the recognition and uptake of a variety of macromolecules, including modified lipoproteins, advanced glycation end (AGEs) products and amyloid b-protein (Abeta)
- While the normal role of CD206 is associated with cell adhesion and host defense mechanisms, it also has been implicated in the development of atherosclerosis and Amyloid beta deposition in Alzheimer's disease (AD)
- CD206’s gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing
- The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs)
- The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms
- CD206 has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis
- The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages
- Other diseases associated with CD206 dysfunction include leprosy and Gaucher’s Disease.
Compare Similar Items
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Antigen: CD206 (MMR)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P22897
Gene Symbols: Mrc1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4360
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: 19.2
Conjugate: Brilliant Violet 421
Gene: Mrc1
Gene Alias: AW259686; bA541I19.1; CD206; CELE_Y39A3CR.4; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; ddp-1; hMR; Human mannose receptor; macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; Mitochondrial import inner membrane translocase subunit Tim8; MMR; MR; MRC1; MRC1L1; tim-8; Y39A3CR.4
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Antigen:
CD206 (MMR)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P22897
Gene Symbols:
Mrc1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4360
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
19.2
Conjugate:
Brilliant Violet 421
Gene:
Mrc1
Gene Alias:
AW259686; bA541I19.1; CD206; CELE_Y39A3CR.4; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; ddp-1; hMR; Human mannose receptor; macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; Mitochondrial import inner membrane translocase subunit Tim8; MMR; MR; MRC1; MRC1L1; tim-8; Y39A3CR.4
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Antigen: CD279 (PD-1)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: Q15116
Gene Symbols: Pdcd1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100135775, 5133
Content And Storage: 4°, C, store in dark, DO NOT FREEZE!
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: eBioJ105 (J105)
Conjugate: Brilliant Violet 421
Gene: Pdcd1
Gene Alias: CD279, EGK_05005, hPD1, hPD-1, hPD-l, hSLE1, Ly101, mPD-1, PD1, PD-1, Pdc1, Pdcd1, programmed cell death 1, programmed cell death 1 protein, programmed cell death protein 1, programmed cell death protein 1-like, programmed death 1, Protein PD1, protein PD-1, sCD279, SLEB2, soluble CD279, systemic lupus erythematosus susceptibility 2
Host Species: Mouse
Quantity: 25 Tests
Primary or Secondary: Primary
Target Species: Human, Rhesus Monkey
Form: Liquid
Antigen:
CD279 (PD-1)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
Q15116
Gene Symbols:
Pdcd1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100135775, 5133
Content And Storage:
4°, C, store in dark, DO NOT FREEZE!
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
eBioJ105 (J105)
Conjugate:
Brilliant Violet 421
Gene:
Pdcd1
Gene Alias:
CD279, EGK_05005, hPD1, hPD-1, hPD-l, hSLE1, Ly101, mPD-1, PD1, PD-1, Pdc1, Pdcd1, programmed cell death 1, programmed cell death 1 protein, programmed cell death protein 1, programmed cell death protein 1-like, programmed death 1, Protein PD1, protein PD-1, sCD279, SLEB2, soluble CD279, systemic lupus erythematosus susceptibility 2
Host Species:
Mouse
Quantity:
25 Tests
Primary or Secondary:
Primary
Target Species:
Human, Rhesus Monkey
Form:
Liquid
Antigen: CD279 (PD-1)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.: Q15116
Gene Symbols: Pdcd1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100135775, 5133
Content And Storage: 4°, C, store in dark, DO NOT FREEZE!
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: eBioJ105 (J105)
Conjugate: Brilliant Violet 421
Gene: Pdcd1
Gene Alias: CD279, EGK_05005, hPD1, hPD-1, hPD-l, hSLE1, Ly101, mPD-1, PD1, PD-1, Pdc1, Pdcd1, programmed cell death 1, programmed cell death 1 protein, programmed cell death protein 1, programmed cell death protein 1-like, programmed death 1, Protein PD1, protein PD-1, sCD279, SLEB2, soluble CD279, systemic lupus erythematosus susceptibility 2
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human, Rhesus Monkey
Form: Liquid
Antigen:
CD279 (PD-1)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Accession No.:
Q15116
Gene Symbols:
Pdcd1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100135775, 5133
Content And Storage:
4°, C, store in dark, DO NOT FREEZE!
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
eBioJ105 (J105)
Conjugate:
Brilliant Violet 421
Gene:
Pdcd1
Gene Alias:
CD279, EGK_05005, hPD1, hPD-1, hPD-l, hSLE1, Ly101, mPD-1, PD1, PD-1, Pdc1, Pdcd1, programmed cell death 1, programmed cell death 1 protein, programmed cell death protein 1, programmed cell death protein 1-like, programmed death 1, Protein PD1, protein PD-1, sCD279, SLEB2, soluble CD279, systemic lupus erythematosus susceptibility 2
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human, Rhesus Monkey
Form:
Liquid
Antigen: Connexin 37
Classification: Polyclonal
Concentration: 0.25 mg/mL
Formulation: PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.: P28235
Gene Symbols: GJA4
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14612
Content And Storage: -20°C
Isotype: IgG
Applications: Immunohistochemistry (Frozen), Western Blot
Clone: __
Conjugate: Unconjugated
Gene: GJA4
Gene Alias: AU020209; AW558810; Cnx37; connexin 37; connexin-37; CX37; CXN37; Cxn-37; gap junction alpha-4 protein; gap junction membrane channel protein alpha 4; Gap junction membrane channel, protein alpha 4 (connexin 37); gap junction protein alpha 4; gap junction protein, alpha 4; gap junction protein, alpha 4, 37kDa; GJA4; Gja-4
Host Species: Rabbit
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Form: Liquid
Antigen:
Connexin 37
Classification:
Polyclonal
Concentration:
0.25 mg/mL
Formulation:
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.:
P28235
Gene Symbols:
GJA4
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14612
Content And Storage:
-20°C
Isotype:
IgG
Applications:
Immunohistochemistry (Frozen), Western Blot
Clone:
__
Conjugate:
Unconjugated
Gene:
GJA4
Gene Alias:
AU020209; AW558810; Cnx37; connexin 37; connexin-37; CX37; CXN37; Cxn-37; gap junction alpha-4 protein; gap junction membrane channel protein alpha 4; Gap junction membrane channel, protein alpha 4 (connexin 37); gap junction protein alpha 4; gap junction protein, alpha 4; gap junction protein, alpha 4, 37kDa; GJA4; Gja-4
Host Species:
Rabbit
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Liquid