40-720-6942
CD206 (MMR) Monoclonal Antibody (19.2), Brilliant Violet™ 711, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 40-720-6942-Each-of-1 | In Stock | ₹ 30,716.04 |
40-720-6942 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,716.04
GST (18%): ₹ 5,528.887
Total Price: ₹ 36,244.927
Antigen
CD206 (MMR)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P22897
Gene Symbols
Mrc1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4360
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
19.2
Conjugate
Brilliant Violet 711
Gene
Mrc1
Gene Alias
AW259686; bA541I19.1; CD206; CELE_Y39A3CR.4; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; ddp-1; hMR; Human mannose receptor; macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; Mitochondrial import inner membrane translocase subunit Tim8; MMR; MR; MRC1; MRC1L1; tim-8; Y39A3CR.4
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Related Products
Description
- CD206 (MSR, Mannose receptor, MRC1) is a 175 kDa transmembrane protein belonging to the group of pattern recognition receptors
- CD206 is predominantly expressed in tissue macrophages, dendritic cells, a subpopulation of endothelial cells and sperm cells
- CD206 is thought to play a role in the innate and adaptive immune response
- CD206 is also expressed on microglia and mato cells of the brain but not astrocytes or neurons
- CD206 also mediate the recognition and uptake of a variety of macromolecules, including modified lipoproteins, advanced glycation end (AGEs) products and amyloid b-protein (Abeta)
- While the normal role of CD206 is associated with cell adhesion and host defense mechanisms, it also has been implicated in the development of atherosclerosis and Amyloid beta deposition in Alzheimer's disease (AD)
- CD206’s gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing
- The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs)
- The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms
- CD206 has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis
- The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages
- Other diseases associated with CD206 dysfunction include leprosy and Gaucher’s Disease.
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Antigen: CD206 (MMR)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P22897
Gene Symbols: Mrc1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4360
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: 19.2
Conjugate: Brilliant Violet 711
Gene: Mrc1
Gene Alias: AW259686; bA541I19.1; CD206; CELE_Y39A3CR.4; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; ddp-1; hMR; Human mannose receptor; macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; Mitochondrial import inner membrane translocase subunit Tim8; MMR; MR; MRC1; MRC1L1; tim-8; Y39A3CR.4
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Antigen:
CD206 (MMR)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P22897
Gene Symbols:
Mrc1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4360
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
19.2
Conjugate:
Brilliant Violet 711
Gene:
Mrc1
Gene Alias:
AW259686; bA541I19.1; CD206; CELE_Y39A3CR.4; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; ddp-1; hMR; Human mannose receptor; macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; Mitochondrial import inner membrane translocase subunit Tim8; MMR; MR; MRC1; MRC1L1; tim-8; Y39A3CR.4
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: 2°C to 8°C
Isotype: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Gene Alias: __
Host Species: __
Quantity: 1 Kit
Primary or Secondary: __
Target Species: __
Form: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
__
Regulatory Status:
__
Gene ID (Entrez):
__
Content And Storage:
2°C to 8°C
Isotype:
__
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Gene Alias:
__
Host Species:
__
Quantity:
1 Kit
Primary or Secondary:
__
Target Species:
__
Form:
__
Antigen: CD223 (LAG-3)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P18627
Gene Symbols: LAG3
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3902
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: 3DS223H
Conjugate: Brilliant Violet 711
Gene: LAG3
Gene Alias: Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3
Host Species: Mouse
Quantity: 25 Tests
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Antigen:
CD223 (LAG-3)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P18627
Gene Symbols:
LAG3
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3902
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
3DS223H
Conjugate:
Brilliant Violet 711
Gene:
LAG3
Gene Alias:
Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3
Host Species:
Mouse
Quantity:
25 Tests
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Antigen: CD223 (LAG-3)
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P18627
Gene Symbols: LAG3
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3902
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: 3DS223H
Conjugate: Brilliant Violet 711
Gene: LAG3
Gene Alias: Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Antigen:
CD223 (LAG-3)
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P18627
Gene Symbols:
LAG3
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3902
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
3DS223H
Conjugate:
Brilliant Violet 711
Gene:
LAG3
Gene Alias:
Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid