40-470-0

Occludin Polyclonal Antibody, Invitrogen™

Manufacturer: Invitrogen

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Pack Size SKU Availability Price
Each of 1 40-470-0-Each-of-1 In Stock ₹ 38,502.00

40-470-0 - Each of 1

₹ 38,502.00

In Stock

Quantity

1

Base Price: ₹ 38,502.00

GST (18%): ₹ 6,930.36

Total Price: ₹ 45,432.36

Antigen

Occludin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

OCLN

Gene Alias

AI503564; BLCPMG; Occludin; occludin 1B; Ocl; Ocln; phosphatase 1, regulatory subunit 115; PPP1R115; tight junction protein occludin; tight junction structural protein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100506658, 18260, 403844, 83497

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.25 mg/mL

Formulation

PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.

Q16625, Q28269, Q61146, Q6P6T5

Gene Symbols

OCLN

Immunogen

Synthetic peptide derived from the C-terminal region of the human occludin protein

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Canine, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is specific for the human occludin protein
  • On western blots, it identifies the target band at ∽65 kDa
  • Reactivity has been confirmed with human Caco-2 and HT29, dog MDCK, mouse TCMK, and rat KNRK cell lysates, and mouse kidney, liver, and rat liver homogenates by western blotting, Caco-2 cells by immunofluorescence, and paraffin-embedded human small intestine tissue by immunohistochemistry
  • For immunofluorescence using Caco-2 cells, fixation with cold ethanol is recommended
  • For immunohistochemistry in paraffin-embedded tissues, enzyme digestion with pepsin is required prior to staining
  • Occludin is a 65 kDa protein that can exist in a variety of phosphorylated forms, ranging up to approximately 82 kDa
  • Occludin is thought to be involved in regulating both the localization and the function of occludin
  • Polyunsaturated fatty acids are known to up-regulate occludin expression, increasing the transendothelial cell resistance and reducing the cellular permeability to large molecules
  • The level of occludin varies greatly depending on tissue; in brain tissue, occludin is highly and continuously expressed at cell-cell contact sites, whereas non-neural tissues show lower expression and discontinuous distribution
  • Overall structural features of the occludin protein are highly conserved in all the species examined
  • Under-expression of tight junction proteins, including occludin, is a key molecular abnormality responsible for the increased permeability of tumor endothelial tight junctions, which contributes to brain tumor edemas.

Compare Similar Items

Show Difference

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Invitrogen

40-470-0

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Antigen:
Occludin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
OCLN

Gene Alias:
AI503564; BLCPMG; Occludin; occludin 1B; Ocl; Ocln; phosphatase 1, regulatory subunit 115; PPP1R115; tight junction protein occludin; tight junction structural protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100506658, 18260, 403844, 83497

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.25 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
Q16625, Q28269, Q61146, Q6P6T5

Gene Symbols:
OCLN

Immunogen:
Synthetic peptide derived from the C-terminal region of the human occludin protein

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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Fischer Scientific

40-471-6941

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Antigen:
IL-17F

Classification:
Monoclonal

Conjugate:
Brilliant Violet 421

Gene:
IL17F

Gene Alias:
C87042, CANDF6, cytokine ML-1, IL17F, IL-17F, IL-24, ILN, Interleukin, interleukin 17F, Interleukin17F, interleukin-17F, interleukin-24, ML1, ML-1, mutant IL-17F

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
112744

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Concentration:
5 μL/Test

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
Q96PD4

Gene Symbols:
IL17F

Immunogen:
__

Quantity:
25 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
__

Isotype:
IgG1 κ

Img

Fischer Scientific

40-471-6942

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Antigen:
IL-17F

Classification:
Monoclonal

Conjugate:
Brilliant Violet 421

Gene:
IL17F

Gene Alias:
C87042, CANDF6, cytokine ML-1, IL17F, IL-17F, IL-24, ILN, Interleukin, interleukin 17F, Interleukin17F, interleukin-17F, interleukin-24, ML1, ML-1, mutant IL-17F

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
112744

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Concentration:
5 μL/Test

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
Q96PD4

Gene Symbols:
IL17F

Immunogen:
__

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
__

Isotype:
IgG1 κ

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Invitrogen

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Antigen:
IL-17A

Classification:
Monoclonal

Conjugate:
Brilliant Violet 421

Gene:
IL17A

Gene Alias:
Ctla8; CTLA-8; cytokine; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; Il17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17 precursor; interleukin 17A; interleukin-17; Interleukin17A; interleukin-17A; R-IL-17-A

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16171, 301289

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q61453, Q62386

Gene Symbols:
IL17A

Immunogen:
__

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2a κ