40-230-0
ZO-1 Polyclonal Antibody (ZMD.437), Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 40-230-0-Each-of-1 | In Stock | ₹ 43,293.36 |
40-230-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,293.36
GST (18%): ₹ 7,792.805
Total Price: ₹ 51,086.165
Antigen
ZO-1
Classification
Polyclonal
Concentration
0.25 mg/mL
Formulation
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.
O97758, P39447, Q07157
Gene Symbols
TJP1
Immunogen
Synthetic peptide derived from the N-terminal region of human, dog, mouse, and rat ZO-1
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Canine, Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone
ZMD.437
Conjugate
Unconjugated
Gene
TJP1
Gene Alias
DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; Tjp1; zo1; ZO-1; ZO-1 MDCK; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
21872, 292994, 403752, 7082
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- This antibody reacts with the ZO-1 protein
- Based on sequence homology, reactivity with ZO-2 or ZO-3 is not expected
- 40-2300 has been successfully used in immunofluorescence and immunohistochemistry
- However, for western blotting we recommend the use of monoclonal anti-ZO-1 antibody (Cat
- No
- 339100), or other polyclonal ZO-1 antibodies (Cat
- Nos
- 617300 or 402200)
- Reactivity has been confirmed with MDCK-II, Caco-2, Rat-1, and NRK52E cells by immunofluorescence
- Reactivity has also been confirmed with frozen mouse liver, blood vessel (in heart), and mossy fiber terminal (in brain) tissues by immunohistochemistry and immunofluorescence, and with formalin-fixed, paraffin-embedded human pancreas, prostate, and small intestine tissues by immunohistochemistry
- This antibody (or Cat
- No
- 187430) is recommended for immunohistochemical detection of ZO-1
- For immunohistochemistry in formalin-fixed, paraffin-embedded tissues, tissue pretreatment with pepsin is required prior to staining
- Some lots of this antibody have successfully been used in western blotting using human, dog and rat cell lysates
- For immunofluorescence methanol fixation is preferred even though paraformaldehyde fixation will also work
- ZO-1 forms complexes with either ZO-2 or ZO-3
- In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction
- ZO-1 expression is significantly reduced in many breast cancer lines
- ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue
- ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions
- ZO-1 may be involved in signal transduction at cell-cell junctions
- Two transcript variants encoding distinct isoforms have been identified for the ZO-1 gene
- Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic Syndrome.
Compare Similar Items
Show Difference
Antigen: ZO-1
Classification: Polyclonal
Concentration: 0.25 mg/mL
Formulation: PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.: O97758, P39447, Q07157
Gene Symbols: TJP1
Immunogen: Synthetic peptide derived from the N-terminal region of human, dog, mouse, and rat ZO-1
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Canine, Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone: ZMD.437
Conjugate: Unconjugated
Gene: TJP1
Gene Alias: DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; Tjp1; zo1; ZO-1; ZO-1 MDCK; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 21872, 292994, 403752, 7082
Content And Storage: -20°C
Form: Liquid
Antigen:
ZO-1
Classification:
Polyclonal
Concentration:
0.25 mg/mL
Formulation:
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.:
O97758, P39447, Q07157
Gene Symbols:
TJP1
Immunogen:
Synthetic peptide derived from the N-terminal region of human, dog, mouse, and rat ZO-1
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone:
ZMD.437
Conjugate:
Unconjugated
Gene:
TJP1
Gene Alias:
DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; Tjp1; zo1; ZO-1; ZO-1 MDCK; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
21872, 292994, 403752, 7082
Content And Storage:
-20°C
Form:
Liquid
Antigen: Arfaptin 2
Classification: Polyclonal
Concentration: 0.25 mg/mL
Formulation: PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.: P53365, Q6AY65, Q8K221
Gene Symbols: ARFIP2
Immunogen: Synthetic peptide derived from the N-terminal region of the human Arfaptin 2 protein (ADP-ribosylation factor interacting protein 2, AFP2, Partner of Rac1, or POR1)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Clone: __
Conjugate: Unconjugated
Gene: ARFIP2
Gene Alias: 2310002N04Rik; ADP ribosylation factor interacting protein 2; ADP-ribosylation factor interacting protein 2; ADP-ribosylation factor interacting protein 2 (arfaptin 2); ADP-ribosylation factor-interacting protein 2; Arfaptin 2; arfaptin-2; Arfip2; Partner of RAC1; partner of RAC1 (arfaptin 2); POR; POR1; Protein POR1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23647, 293344, 76932
Content And Storage: -20°C
Form: Liquid
Antigen:
Arfaptin 2
Classification:
Polyclonal
Concentration:
0.25 mg/mL
Formulation:
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.:
P53365, Q6AY65, Q8K221
Gene Symbols:
ARFIP2
Immunogen:
Synthetic peptide derived from the N-terminal region of the human Arfaptin 2 protein (ADP-ribosylation factor interacting protein 2, AFP2, Partner of Rac1, or POR1)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Clone:
__
Conjugate:
Unconjugated
Gene:
ARFIP2
Gene Alias:
2310002N04Rik; ADP ribosylation factor interacting protein 2; ADP-ribosylation factor interacting protein 2; ADP-ribosylation factor interacting protein 2 (arfaptin 2); ADP-ribosylation factor-interacting protein 2; Arfaptin 2; arfaptin-2; Arfip2; Partner of RAC1; partner of RAC1 (arfaptin 2); POR; POR1; Protein POR1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23647, 293344, 76932
Content And Storage:
-20°C
Form:
Liquid
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Immunogen: __
Quantity: 1mg
Primary or Secondary: __
Target Species: __
Product Type: α-Amanitin
Isotype: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Gene Alias: __
Host Species: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: Store at -20°C
Form: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
__
Quantity:
1mg
Primary or Secondary:
__
Target Species:
__
Product Type:
α-Amanitin
Isotype:
__
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Gene Alias:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Gene ID (Entrez):
__
Content And Storage:
Store at -20°C
Form:
__
Antigen: ZONAB
Classification: Polyclonal
Concentration: 0.25 mg/mL
Formulation: PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.: Q62764, Q9JKB3
Gene Symbols: YBX3
Immunogen: Synthetic peptide derived from an internal region of mouse ZONAB (ZO-1 associated nucleic acid-binding protein
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone: __
Conjugate: Unconjugated
Gene: YBX3
Gene Alias: cold shock domain protein A; cold shock domain-containing protein A; cold-shock domain containing A1; cold-shock domain protein A; Csda; CSDA1; Dbpa; DNA-binding protein A; Dpba; MSY3; MSY4; Muscle Y-box protein YB2; oxyR; RYB-A; single-strand DNA-binding protein NF-GMB; Y box binding protein 3; Y box protein 3; Yb2; Y-box binding protein 3; Y-box protein 3; Y-box-binding protein 3; Y-box-binding protein A; Ybx3; ZO-1-associated nucleic acid-binding protein; ZONAB; ZONAB A; ZONAB B
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 56449, 83807
Content And Storage: Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Form: Liquid
Antigen:
ZONAB
Classification:
Polyclonal
Concentration:
0.25 mg/mL
Formulation:
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.:
Q62764, Q9JKB3
Gene Symbols:
YBX3
Immunogen:
Synthetic peptide derived from an internal region of mouse ZONAB (ZO-1 associated nucleic acid-binding protein
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone:
__
Conjugate:
Unconjugated
Gene:
YBX3
Gene Alias:
cold shock domain protein A; cold shock domain-containing protein A; cold-shock domain containing A1; cold-shock domain protein A; Csda; CSDA1; Dbpa; DNA-binding protein A; Dpba; MSY3; MSY4; Muscle Y-box protein YB2; oxyR; RYB-A; single-strand DNA-binding protein NF-GMB; Y box binding protein 3; Y box protein 3; Yb2; Y-box binding protein 3; Y-box protein 3; Y-box-binding protein 3; Y-box-binding protein A; Ybx3; ZO-1-associated nucleic acid-binding protein; ZONAB; ZONAB A; ZONAB B
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
56449, 83807
Content And Storage:
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Form:
Liquid