40-608-6282

CD86 (B7-2) Monoclonal Antibody (GL1), Brilliant Violet™ 605, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 40-608-6282-Each-of-1 In Stock ₹ 30,716.04

40-608-6282 - Each of 1

₹ 30,716.04

In Stock

Quantity

1

Base Price: ₹ 30,716.04

GST (18%): ₹ 5,528.887

Total Price: ₹ 36,244.927

Antigen

CD86 (B7-2)

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P42082

Gene Symbols

CD86

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12524

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

GL1

Conjugate

Brilliant Violet 605

Gene

CD86

Gene Alias

activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2

Host Species

Rat

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Form

Liquid

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Description

  • CD86 is one of two ligands (the other CD80) for CTLA4 and CD28
  • CD86 acts as costimulatory molecule in eliciting T-cell help during antigen presentation
  • Antigen presentation in the absence of sufficient co-stimulation involving CD86/CD80 can induce tolerance
  • CD80 appears to play a role distinct from CD80 in T helper cell differentiation
  • CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily
  • The CD86 protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4
  • Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell
  • Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response
  • Alternative splicing results in two transcript variants encoding different isoforms of CD86
  • Additional transcript variants have been described for CD86, but their full-length sequences have not been determined
  • Diseases associated with CD86 dysfunction include gallbladder squamous cell carcinoma and myocarditis.

Compare Similar Items

Show Difference

Img

Fischer Scientific

40-608-6282

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Antigen:
CD86 (B7-2)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P42082

Gene Symbols:
CD86

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12524

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
GL1

Conjugate:
Brilliant Violet 605

Gene:
CD86

Gene Alias:
activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

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Invitrogen

40-610-0

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Antigen:
Occludin

Classification:
Polyclonal

Concentration:
0.25 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.:
Q16625

Gene Symbols:
OCLN

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100506658

Content And Storage:
-20°C

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
__

Conjugate:
Unconjugated

Gene:
OCLN

Gene Alias:
AI503564; BLCPMG; Occludin; occludin 1B; Ocl; Ocln; phosphatase 1, regulatory subunit 115; PPP1R115; tight junction protein occludin; tight junction structural protein

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

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Antigen:
CD170 (Siglec F)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q920G3

Gene Symbols:
Siglecf

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
233186

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
1RNM44N

Conjugate:
Brilliant Violet 605

Gene:
Siglecf

Gene Alias:
CD170; CD33 antigen-like 2; CD33L2; mSiglec-F; OB-binding protein 2; OBBP2; OB-BP2; Obesity-binding protein 2; sialic acid binding Ig like lectin 5; sialic acid binding Ig-like lectin 5; sialic acid binding Ig-like lectin F; sialic acid-binding Ig-like lectin 5; Sialic acid-binding Ig-like lectin F; sialic acid-binding immunoglobulin-like lectin 5; sialic acid-binding lectin Siglec-F; Siglec; SIGLEC5; siglec-5; Siglecf; Siglec-F

Host Species:
Rat

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Img

Fischer Scientific

40-617-0282

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Antigen:
CD170 (Siglec F)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q920G3

Gene Symbols:
Siglecf

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
233186

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
1RNM44N

Conjugate:
Brilliant Violet 605

Gene:
Siglecf

Gene Alias:
CD170; CD33 antigen-like 2; CD33L2; mSiglec-F; OB-binding protein 2; OBBP2; OB-BP2; Obesity-binding protein 2; sialic acid binding Ig like lectin 5; sialic acid binding Ig-like lectin 5; sialic acid binding Ig-like lectin F; sialic acid-binding Ig-like lectin 5; Sialic acid-binding Ig-like lectin F; sialic acid-binding immunoglobulin-like lectin 5; sialic acid-binding lectin Siglec-F; Siglec; SIGLEC5; siglec-5; Siglecf; Siglec-F

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid