41-708-6280

CD86 (B7-2) Monoclonal Antibody (GL1), Brilliant Violet™ 786, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 41-708-6280-Each-of-1 In Stock ₹ 14,973.00

41-708-6280 - Each of 1

₹ 14,973.00

In Stock

Quantity

1

Base Price: ₹ 14,973.00

GST (18%): ₹ 2,695.14

Total Price: ₹ 17,668.14

Antigen

CD86 (B7-2)

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P42082

Gene Symbols

CD86

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12524

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

GL1

Conjugate

Brilliant Violet 786

Gene

CD86

Gene Alias

activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2

Host Species

Rat

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Mouse

Form

Liquid

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Description

  • CD86 is one of two ligands (the other CD80) for CTLA4 and CD28
  • CD86 acts as costimulatory molecule in eliciting T-cell help during antigen presentation
  • Antigen presentation in the absence of sufficient co-stimulation involving CD86/CD80 can induce tolerance
  • CD80 appears to play a role distinct from CD80 in T helper cell differentiation
  • CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily
  • The CD86 protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4
  • Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell
  • Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response
  • Alternative splicing results in two transcript variants encoding different isoforms of CD86
  • Additional transcript variants have been described for CD86, but their full-length sequences have not been determined
  • Diseases associated with CD86 dysfunction include gallbladder squamous cell carcinoma and myocarditis.

Compare Similar Items

Show Difference

Img

Fischer Scientific

41-708-6280

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Antigen:
CD86 (B7-2)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P42082

Gene Symbols:
CD86

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12524

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
GL1

Conjugate:
Brilliant Violet 786

Gene:
CD86

Gene Alias:
activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2

Host Species:
Rat

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Img

Fischer Scientific

41-708-6282

--


Antigen:
CD86 (B7-2)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P42082

Gene Symbols:
CD86

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12524

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
GL1

Conjugate:
Brilliant Violet 786

Gene:
CD86

Gene Alias:
activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Img

Fischer Scientific

41-711-7180

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Antigen:
CD117 (c-Kit)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
P05532, Q2HWD6

Gene Symbols:
KIT

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16590, 396810

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
2B8

Conjugate:
Brilliant Violet 786

Gene:
KIT

Gene Alias:
belly-spot, Bs, CD117, ckit, C-Kit, c-KIT gene1, c-kit protein, c-kit proto-oncogene protein, c-kit receptor, c-kit receptor tyrosine kinase, dominant spotting, Dominant white spotting, Fdc, Gsfsco1, Gsfsco5, Gsfsow3, KIT, kit oncogene, KIT proto-oncogene receptor tyrosine kinase, KIT proto-oncogene, receptor tyrosine kinase, mast cell growth factor receptor, mast/stem cell growth factor receptor, mast/stem cell growth factor receptor Kit, MGF, p145 c-kit, PBT, Piebald trait protein, protein kinase, proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, receptor tyrosine kinase c-kit, receptor tyrosine kinase type III, SCFR, SCO1, SCO5, Sl, soluble KIT variant 1, SOW3, spotted sterile male, Ssm, Steel Factor Receptor, Tr-kit, tyrosine kinase receptor, tyrosine kinase receptor c-KIT, tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein, W

Host Species:
Rat

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Porcine

Form:
Liquid

Img

Fischer Scientific

41-711-7182

--


Antigen:
CD117 (c-Kit)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Accession No.:
P05532, Q2HWD6

Gene Symbols:
KIT

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16590, 396810

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
2B8

Conjugate:
Brilliant Violet 786

Gene:
KIT

Gene Alias:
belly-spot, Bs, CD117, ckit, C-Kit, c-KIT gene1, c-kit protein, c-kit proto-oncogene protein, c-kit receptor, c-kit receptor tyrosine kinase, dominant spotting, Dominant white spotting, Fdc, Gsfsco1, Gsfsco5, Gsfsow3, KIT, kit oncogene, KIT proto-oncogene receptor tyrosine kinase, KIT proto-oncogene, receptor tyrosine kinase, mast cell growth factor receptor, mast/stem cell growth factor receptor, mast/stem cell growth factor receptor Kit, MGF, p145 c-kit, PBT, Piebald trait protein, protein kinase, proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, receptor tyrosine kinase c-kit, receptor tyrosine kinase type III, SCFR, SCO1, SCO5, Sl, soluble KIT variant 1, SOW3, spotted sterile male, Ssm, Steel Factor Receptor, Tr-kit, tyrosine kinase receptor, tyrosine kinase receptor c-KIT, tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein, W

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Porcine

Form:
Liquid