40-680-0
DISC1 Polyclonal Antibody, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 40-680-0-Each-of-1 | In Stock | ₹ 38,502.00 |
40-680-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,502.00
GST (18%): ₹ 6,930.36
Total Price: ₹ 45,432.36
Antigen
DISC1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DISC1
Gene Alias
C1orf136; DISC1; disrupted in schizophrenia 1; disrupted in schizophrenia 1 homolog; Disrupted in schizophrenia 1 protein; KIAA0457; RP4-730B13.1; SCZD9
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
244667, 27185
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration
0.25 mg/mL
Formulation
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.
Q811T9, Q9NRI5
Gene Symbols
DISC1
Immunogen
Synthetic peptide derived from the C-terminal region of the mouse DISC1 (disrupted in schizophrenia 1) protein
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- DISC1 (Disrupted in Schizophrenia 1) is a multifunctional protein that interacts with multiple proteins of the centrosome and cytoskeletal system, and is involved in neuronal functions that are dependent upon proper cytoskeletal regulation, including neuronal migration, neurite architecture and intracellular transport
- Regions of the brain which express DISC1 include the hippocampus, lateral septum, amygdala, cerebral cortex, cerebellum and paraventricular hypothalamus, and loss of DISC1 function results in differences in structural organization.The DISC1 gene locus is associated with patients afflicted with schizophrenia as a result of chromosomal translocations
- DISC-1 encodes a large protein predicted to contain a globular N-terminal domain and a helical C-terminal domain, both of which have the potential to form interactions with other proteins
- DISC-1 interacts with proteins involved in the centrosome and cytoskeletal system, including MIPT3, MAP1A and NUDEL; proteins which localize receptors to membranes, including alpha-actinin 2, beta 4-spectrin; and proteins which transduce signals from membrane receptors, including ATF-4 and ATF-5
- Therefore, DISC-1 is thought to be involved in intracellular transport, neurite architecture and/or neuronal migration, all of which are thought to be pathogenic in the schizophrenic brain
- Decreased expression of DISC1 in neurons caused an accelerated rate of neuronal integration, resulting in aberrant morphological development, suggesting that DISC1 plays a role in dendritic development and synapse formation
- DISC-1 is thought to be involved in intracellular transport, neurite architecture and/or neuronal migration, all of which are thought to be pathogenic in the schizophrenic brain.
Compare Similar Items
Show Difference
Antigen: DISC1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DISC1
Gene Alias: C1orf136; DISC1; disrupted in schizophrenia 1; disrupted in schizophrenia 1 homolog; Disrupted in schizophrenia 1 protein; KIAA0457; RP4-730B13.1; SCZD9
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 244667, 27185
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.25 mg/mL
Formulation: PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.: Q811T9, Q9NRI5
Gene Symbols: DISC1
Immunogen: Synthetic peptide derived from the C-terminal region of the mouse DISC1 (disrupted in schizophrenia 1) protein
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
DISC1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DISC1
Gene Alias:
C1orf136; DISC1; disrupted in schizophrenia 1; disrupted in schizophrenia 1 homolog; Disrupted in schizophrenia 1 protein; KIAA0457; RP4-730B13.1; SCZD9
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
244667, 27185
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.25 mg/mL
Formulation:
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.:
Q811T9, Q9NRI5
Gene Symbols:
DISC1
Immunogen:
Synthetic peptide derived from the C-terminal region of the mouse DISC1 (disrupted in schizophrenia 1) protein
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: DISC1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DISC1
Gene Alias: C1orf136; DISC1; disrupted in schizophrenia 1; disrupted in schizophrenia 1 homolog; Disrupted in schizophrenia 1 protein; KIAA0457; RP4-730B13.1; SCZD9
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 244667, 27185, 307940
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Concentration: 0.25 mg/mL
Formulation: PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.: Q810H6, Q811T9, Q9NRI5
Gene Symbols: DISC1
Immunogen: Synthetic peptide derived from an internal region of the mouse DISC1 (disrupted in schizophrenia 1) isoforms 1 and 2, which differ from rat by one amino acid
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
DISC1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DISC1
Gene Alias:
C1orf136; DISC1; disrupted in schizophrenia 1; disrupted in schizophrenia 1 homolog; Disrupted in schizophrenia 1 protein; KIAA0457; RP4-730B13.1; SCZD9
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
244667, 27185, 307940
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Concentration:
0.25 mg/mL
Formulation:
PBS with 0.1% sodium azide; pH 7.4
Gene Accession No.:
Q810H6, Q811T9, Q9NRI5
Gene Symbols:
DISC1
Immunogen:
Synthetic peptide derived from an internal region of the mouse DISC1 (disrupted in schizophrenia 1) isoforms 1 and 2, which differ from rat by one amino acid
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Gata-3
Classification: Monoclonal
Conjugate: Brilliant Violet 605
Gene: GATA3
Gene Alias: EGK_19445; GATA binding factor-3; GATA binding protein 3; GATA binding protein-3; GATA3; Gata-3; GATA-binding factor 3; GATA-binding protein 3; HDR; HDRS; jal; MGC2346; MGC5199; MGC5445; Trans-acting T-cell-specific transcription factor GATA-3; Transacting T-cell-specific transcription factor GATA-3
Host Species: Rat
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14462, 2625, 713840, 733631
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Concentration: 5 μL/Test
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P23771, P23772
Gene Symbols: __
Immunogen: __
Quantity: 25 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse, Porcine, Rhesus Monkey
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
Gata-3
Classification:
Monoclonal
Conjugate:
Brilliant Violet 605
Gene:
GATA3
Gene Alias:
EGK_19445; GATA binding factor-3; GATA binding protein 3; GATA binding protein-3; GATA3; Gata-3; GATA-binding factor 3; GATA-binding protein 3; HDR; HDRS; jal; MGC2346; MGC5199; MGC5445; Trans-acting T-cell-specific transcription factor GATA-3; Transacting T-cell-specific transcription factor GATA-3
Host Species:
Rat
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14462, 2625, 713840, 733631
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Concentration:
5 μL/Test
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P23771, P23772
Gene Symbols:
__
Immunogen:
__
Quantity:
25 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Porcine, Rhesus Monkey
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: Gata-3
Classification: Monoclonal
Conjugate: Brilliant Violet 605
Gene: GATA3
Gene Alias: EGK_19445; GATA binding factor-3; GATA binding protein 3; GATA binding protein-3; GATA3; Gata-3; GATA-binding factor 3; GATA-binding protein 3; HDR; HDRS; jal; MGC2346; MGC5199; MGC5445; Trans-acting T-cell-specific transcription factor GATA-3; Transacting T-cell-specific transcription factor GATA-3
Host Species: Rat
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14462, 2625, 713840, 733631
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Concentration: 5 μL/Test
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P23771, P23772
Gene Symbols: __
Immunogen: __
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse, Porcine, Rhesus Monkey
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
Gata-3
Classification:
Monoclonal
Conjugate:
Brilliant Violet 605
Gene:
GATA3
Gene Alias:
EGK_19445; GATA binding factor-3; GATA binding protein 3; GATA binding protein-3; GATA3; Gata-3; GATA-binding factor 3; GATA-binding protein 3; HDR; HDRS; jal; MGC2346; MGC5199; MGC5445; Trans-acting T-cell-specific transcription factor GATA-3; Transacting T-cell-specific transcription factor GATA-3
Host Species:
Rat
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14462, 2625, 713840, 733631
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Concentration:
5 μL/Test
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P23771, P23772
Gene Symbols:
__
Immunogen:
__
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Porcine, Rhesus Monkey
Product Type:
Antibody
Isotype:
IgG2b κ