41-830-0

LXR alpha Monoclonal Antibody (PPZ0412), Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 41-830-0-Each-of-1 In Stock ₹ 39,015.36

41-830-0 - Each of 1

₹ 39,015.36

In Stock

Quantity

1

Base Price: ₹ 39,015.36

GST (18%): ₹ 7,022.765

Total Price: ₹ 46,038.125

Antigen

LXR alpha

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

physiological saline with 0.1% sodium azide

Gene Accession No.

Q13133, Q62685, Q9Z0Y9

Gene Symbols

NR1H3

Immunogen

Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with E.coli-expressed recombinant human LXR-alpha (164-447 aa).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG2a

Applications

ChIP Assay, ELISA, Gel Shift, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

PPZ0412

Conjugate

Unconjugated

Gene

NR1H3

Gene Alias

AU018371; liver X nuclear receptor alpha variant 1; liver X receptor alpha; LXR; LXR alpha; Lxra; LXR-a; LXRalpha; LXRb; NER; NERI; NR1H2; Nr1h3; nuclear orphan receptor LXR-alpha; nuclear oxysterol receptor LxR-alpha; nuclear receptor subfamily 1 group H member 3; nuclear receptor subfamily 1, group H, member 3; oxysterols receptor LXR-alpha; RLD1; RLD-1; ubiquitously-expressed nuclear receptor 1; Unr1

Host Species

Mouse

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

10062, 22259, 58852

Content And Storage

Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C

Form

Liquid

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Description

  • This antibody specifically recognizes human LXR alpha and cross reacts with mouse and rat LXR alpha
  • This antibody does not recognize human LXR beta
  • NR1H3 (oxysterols receptor LXR-alpha) is a nuclear receptor that exhibits a ligand-dependent transcriptional activation activity
  • Its interaction with retinoic acid receptor (RXR) shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES
  • LXRES are DR4-type response elements characterized by direct repeats of two similar hexanucleotide half-sites spaced by four nucleotides
  • NR1H3 plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR, and LRP8
  • It also interplays functionally with RORA for the regulation of genes involves in liver metabolism.

Compare Similar Items

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Img

Invitrogen

41-830-0

--


Antigen:
LXR alpha

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
physiological saline with 0.1% sodium azide

Gene Accession No.:
Q13133, Q62685, Q9Z0Y9

Gene Symbols:
NR1H3

Immunogen:
Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with E.coli-expressed recombinant human LXR-alpha (164-447 aa).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
ChIP Assay, ELISA, Gel Shift, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
PPZ0412

Conjugate:
Unconjugated

Gene:
NR1H3

Gene Alias:
AU018371; liver X nuclear receptor alpha variant 1; liver X receptor alpha; LXR; LXR alpha; Lxra; LXR-a; LXRalpha; LXRb; NER; NERI; NR1H2; Nr1h3; nuclear orphan receptor LXR-alpha; nuclear oxysterol receptor LxR-alpha; nuclear receptor subfamily 1 group H member 3; nuclear receptor subfamily 1, group H, member 3; oxysterols receptor LXR-alpha; RLD1; RLD-1; ubiquitously-expressed nuclear receptor 1; Unr1

Host Species:
Mouse

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
10062, 22259, 58852

Content And Storage:
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C

Form:
Liquid

Img

Invitrogen

41-910-882

--


Antigen:
ERK1/2

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P21708, P27361, P28482, P63085, P63086, Q63844

Gene Symbols:
MAPK1, MAPK3

Immunogen:
__

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
5AD13MA

Conjugate:
eFluor 570

Gene:
MAPK3

Gene Alias:
12559; 9030612K14Rik; AA407128; AU018647; BcDNA:RE08694; C78273; CG12559; CG12559-PA; CG12559-PC; CG12559-PD; CG12559-PE; CG12559-PG; CG12559-PH; CG12559-PI; CG18732; CT34260; CT39192; DERK; D-ERK; DERK-A; Diphospho-ERK; dm-dpERK; Dmel\CG12559; Dmel_CG12559; DmErk; DmERKA; DmERK-A; DmMAPK; dpERK; dp-ERK; dpERK1; dpMAPK; drosophila ERK; Dsor2; E(sina)7; EC2-1; EK2-1; enhancer of seven in absentia 7; ERK; Erk MAP kinase; Erk/Map kinase; ERK/rolled; Erk1; Erk-1; erk1 erk2; Erk1/2; ERK1b; ERK2; ERK-2; ERKA; ERK-A; ERT1; ERT2; Esrk1; extracellular signal-regulated kinase; extracellular signal-regulated kinase (ERK2); extracellular signal-regulated kinase 1; Extracellular signal-regulated kinase 2; extracellular signal-regulated kinase A; extracellular signal-regulated kinase-1; extracellular signal-regulated kinase-2; extracellular signal-related kinase 1; Extracellular-regulated kinase A; extracellular-signal-regulated kinase 2; Extracellular-signal-related kinase A; EY2-2; fi06b09; GroupI

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116590, 26413, 26417, 50689, 5594, 5595

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

MilliporeSigma™

41-980-05MG

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Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
5 mg

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
Protect from light

Form:
Solid

Img

Invitrogen

41-981-582

--


Antigen:
Cytokeratin 18

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P05783

Gene Symbols:
KRT18

Immunogen:
__

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunohistochemistry

Clone:
LDK18

Conjugate:
eFluor 570

Gene:
KRT18

Gene Alias:
cb83; Cell proliferation-inducing gene 46 protein; CK 18; CK18; CK-18; CYK18; cytokeratin 18; cytokeratin endo B; cytokeratin type -1; DAPK-1; Cytokeratin18; cytokeratin-18; dapk1; dorsal aorta proneprin kinesin-1; DreK18; Endo B; I79_023185; K 18; K18; keratin 18; keratin 18, type I; keratin 18a, tandem duplicate 1; keratin complex 1, acidic, gene 18; keratin D; Keratin, type I cytoskeletal 18; Keratin18; keratin-18; Kerd; KRT 18; Krt1-18; KRT18; krt18 {ECO:0000250; krt18a.1; LOC100008885; PIG46; sb:cb83; type I cytoskeletal 18; UniProtKB:P05783}; wu:fa13f02; wu:fb36b04

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3875

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid