44-233-G

Phospho-Syk (Tyr317) Polyclonal Antibody, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each 44-233-G-Each In Stock ₹ 31,285.01

44-233-G - Each

₹ 31,285.01

In Stock

Quantity

1

Base Price: ₹ 31,285.01

GST (18%): ₹ 5,631.302

Total Price: ₹ 36,916.312

Antigen

Phospho-Syk (Tyr317)

Classification

Polyclonal

Formulation

Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3

Gene Accession No.

P43405, P48025

Gene Symbols

Syk

Immunogen

The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of mouse Syk that contains tyrosine 317 (tyrosine 323 in the human sequence).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Gene

Syk

Gene Alias

DKFZp313N1010; EC 2.7.10.2; FLJ25043; FLJ37489; HGNC:11205; kinase Syk; KSYK; p72Syk; p72-Syk; ptk72; SP1; spleen associated tyrosine kinase; spleen tyrosine kinase; SYK; syk signaling; Sykb; tyrosine-kinase syk; tyrosine-protein kinase SYK

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20963, 6850

Content And Storage

-20°C

Form

Liquid

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Description

  • Spleen tyrosine kinase (SYK), along with ZAP70, are cytoplasmic tyrosine kinases that are viewed as potential druge targets for allergic disorders and autoimmune diseases
  • SYK may also play a role in cancer
  • Syk translocates to the plasma membrane upon B cell antigen receptor (BCR) or the high-affinity IgE receptor (FcepsilonRI) triggering, and phosphorylates downstream adaptor proteins, thereby providing docking sites for initiation of subsequent signaling pathways, such as calcium mobilization, cytoskeleton remodeling, or transcription of specific genes
  • Syk binds to the receptor assemblies through interactions of its pair of SH2 domains with ITAM motives of the receptor, which have been phosphorylated by Src-family kinases
  • These kinases also help to activate Syk by phosphorylation of its activation loop.

Compare Similar Items

Show Difference

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Invitrogen

44-233-G

--


Antigen:
Phospho-Syk (Tyr317)

Classification:
Polyclonal

Formulation:
Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3

Gene Accession No.:
P43405, P48025

Gene Symbols:
Syk

Immunogen:
The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of mouse Syk that contains tyrosine 317 (tyrosine 323 in the human sequence).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
Syk

Gene Alias:
DKFZp313N1010; EC 2.7.10.2; FLJ25043; FLJ37489; HGNC:11205; kinase Syk; KSYK; p72Syk; p72-Syk; ptk72; SP1; spleen associated tyrosine kinase; spleen tyrosine kinase; SYK; syk signaling; Sykb; tyrosine-kinase syk; tyrosine-protein kinase SYK

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20963, 6850

Content And Storage:
-20°C

Form:
Liquid

Img

Invitrogen

44-244-G

--


Antigen:
Phospho-SMAD2 (Ser465, Ser467)

Classification:
Polyclonal

Formulation:
Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3

Gene Accession No.:
Q15796, Q62432

Gene Symbols:
SMAD2

Immunogen:
The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of human Smad2 that contains serines 465 and 467. The sequence is conserved in mouse and rat.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Gene:
SMAD2

Gene Alias:
7120426M23Rik; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; Smad2; Smad-2; Smad2Deltaexon3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17126, 4087

Content And Storage:
-20°C

Form:
Liquid

Img

Invitrogen

44-246-G

--


Antigen:
Phospho-SMAD3 (Ser423, Ser425)

Classification:
Polyclonal

Formulation:
Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3

Gene Accession No.:
P84022, Q8BUN5

Gene Symbols:
Smad3

Immunogen:
The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of human Smad3 that contains serine 423 and serine 425. This sequence is conserved in mouse.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
Smad3

Gene Alias:
AU022421; DKFZp586N0721; DKFZp686J10186; hMAD-3; hSMAD3; HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MAD (mothers against decapentaplegic, Drosophila) homolog 3; MAD homolog 3; MAD homolog 3a; mad homolog JV15-2; mad protein homolog; MAD, mothers against decapentaplegic homolog 3; mad3; MAD-3; madh3; madh3a; madh3-A; MGC60396; mMad3; mothers against decapentaplegic homolog 3; mothers against decapentaplegic homolog 3a; mothers against DPP homolog 3; SMA- and MAD-related protein 3; SMAD; Smad 3; SMAD family member 3; SMAD family member 3 L homeolog; SMAD family member 3a; SMAD, mothers against DPP homolog 3; Smad3; smad3.L; smad3a; TGF beta response effector Smad3; TGF-beta response effector Smad3; transcription factor; transcription factor Smad3; wu:fa99e03; XELAEV_18018454mg; XenMLP; Xmad3; XSmad3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17127, 4088

Content And Storage:
-20°C

Form:
Liquid

Img

Invitrogen

44-250

--


Antigen:
Phospho-c-Abl (Tyr245)

Classification:
Polyclonal

Formulation:
Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3

Gene Accession No.:
P00519

Gene Symbols:
ABL1

Immunogen:
synthesized phosphopeptide derived from a region of human c-Abl that contains tyrosine 245

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
ABL1

Gene Alias:
Abelson murine leukemia oncogene; Abelson murine leukemia viral (v-abl) oncogene homolog 1; abelson murine leukemia viral oncogene homolog 1; Abelson tyrosine-protein kinase 1; Abl; Abl 1 antib; ABL proto-oncogene 1, non-receptor tyrosine kinase; Abl1; ABL2; ABLL; AI325092; ARG; B30; bcr/abl; bcr/c-abl oncogene protein; c-ABL; c-abl oncogene 1, non-receptor tyrosine kinase; c-abl oncogene 1, receptor tyrosine kinase; c-ABL1; E430008G22Rik; JTK7; p150; Proto-oncogene c-Abl; proto-oncogene tyrosine-protein kinase ABL1; RP11-83J21.1; Tyrosine kinase ARG; tyrosine-protein kinase ABL1; v-abl; v-abl Abelson murine leukemia oncogene 1; v-abl Abelson murine leukemia viral oncogene 1; v-abl Abelson murine leukemia viral oncogene homolog 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25

Content And Storage:
-20°C

Form:
Liquid