44-856
Phospho-Cortactin (Tyr466) Polyclonal Antibody, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 44-856-Each-of-1 | In Stock | ₹ 38,502.00 |
44-856 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,502.00
GST (18%): ₹ 6,930.36
Total Price: ₹ 45,432.36
Antigen
Phospho-Cortactin (Tyr466)
Classification
Polyclonal
Formulation
Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3
Gene Accession No.
Q60598
Gene Symbols
Cttn
Immunogen
antiserum was produced against a chemically synthesized phosphopeptide derived from the region of mouse cortactin that contains tyrosine 466 (tyrosine 470 in the human sequence).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
Cttn
Gene Alias
1110020L01Rik; amplaxin; cortactin; Cttn; Cttnb; EMS1; ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate); FLJ34459; mammary tumor and squamous cell carcinoma associated (p80/85 src substrate); oncogene EMS1; Oncogene SRC8; Src substrate cortactin; src8; Unknown (protein for MGC:137923)
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
13043
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- Cortactin (Cttn) is a ubiquitous actin-binding protein that was originally identified as a substrate for Src
- It contributes to the organization of the actin cytoskeleton and cell shape
- Cortactin also plays a role in the formation of lamellipodia and cell migration
- It is accumulated in peripheral, actin-enriched structures of cells suggesting that cortactin facilitates actin network formation
- Cortactin has four major domains of interest the N-terminal acidic (NTA) and tandem repeats domains and the C-terminal proline-rich and SH3 Domains
- NTA associates with the Arp2/3 and WASP complex at F-actin branches
- Cortactin is involved in promoting cell motility and invasion, including a critical role in invadopodia, actin rich-subcellular protrusions associated with degradation of the ECM by cancer cells
- Cortactin is phosphorylated by src family kinases at Y421, Y466, and Y482 and S405 and S418 that are phosphorylated by Erk family kinases.
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Antigen: Phospho-Cortactin (Tyr466)
Classification: Polyclonal
Formulation: Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3
Gene Accession No.: Q60598
Gene Symbols: Cttn
Immunogen: antiserum was produced against a chemically synthesized phosphopeptide derived from the region of mouse cortactin that contains tyrosine 466 (tyrosine 470 in the human sequence).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: Cttn
Gene Alias: 1110020L01Rik; amplaxin; cortactin; Cttn; Cttnb; EMS1; ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate); FLJ34459; mammary tumor and squamous cell carcinoma associated (p80/85 src substrate); oncogene EMS1; Oncogene SRC8; Src substrate cortactin; src8; Unknown (protein for MGC:137923)
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13043
Content And Storage: -20°C
Form: Liquid
Antigen:
Phospho-Cortactin (Tyr466)
Classification:
Polyclonal
Formulation:
Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3
Gene Accession No.:
Q60598
Gene Symbols:
Cttn
Immunogen:
antiserum was produced against a chemically synthesized phosphopeptide derived from the region of mouse cortactin that contains tyrosine 466 (tyrosine 470 in the human sequence).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
Cttn
Gene Alias:
1110020L01Rik; amplaxin; cortactin; Cttn; Cttnb; EMS1; ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate); FLJ34459; mammary tumor and squamous cell carcinoma associated (p80/85 src substrate); oncogene EMS1; Oncogene SRC8; Src substrate cortactin; src8; Unknown (protein for MGC:137923)
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13043
Content And Storage:
-20°C
Form:
Liquid
Antigen: __
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Immunogen: __
Quantity: 1 system
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Content And Storage: Laptop Computer
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Content And Storage:
Desktop Computer
Form:
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