44-568-G

Phospho-GAB1 (Tyr627) Polyclonal Antibody, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each 44-568-G-Each In Stock ₹ 33,252.89

44-568-G - Each

₹ 33,252.89

In Stock

Quantity

1

Base Price: ₹ 33,252.89

GST (18%): ₹ 5,985.52

Total Price: ₹ 39,238.41

Antigen

Phospho-GAB1 (Tyr627)

Classification

Polyclonal

Formulation

Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3

Gene Accession No.

Q13480, Q9QYY0

Gene Symbols

GAB1

Immunogen

The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human Gab1 that contains tyrosine 627. The sequence is conserved in mouse.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Gene

GAB1

Gene Alias

AA408973; AW107238; EGK_16125; GAB1; GRB2 associated binding protein 1; GRB2-associated binder 1; GRB2-associated binding protein 1; GRB2-associated binding protein 1 long isoform; GRB2-associated-binding protein 1; Growth factor receptor bound protein 2-associated protein 1; OTTHUMP00000220263

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14388, 2549

Content And Storage

-20°C

Form

Liquid

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Description

  • Description Gab1 is a 115 kDa multiple docking protein that plays an essential role in cellular growth, transformation and apoptosis
  • Gab1 can be phosphorylated by multiple receptor tyrosine kinase (RTKs), including: insulin receptor (IR), platelet-derived growth factor receptor beta] (PDGFRbeta]), hepatocyte growth factor/scatter factor receptor (HGFR/SFR or c-Met), and epidermal growth factor receptor (EGF), as well as in response to cell-cell adhesion
  • Gab1 is tyrosine phosphorylated on at least 16 sites, some of which serve as binding sites for phosphoatidylinositol 3-kinase (PI3K), Grb2, PLC gamma 1, Nck, and SHP2
  • Phosphorylation of Gab1 on tyrosines 627 and 659 is critical for its binding to SHP2, and for activation of the ERK/MAPK pathway in response to EGF.

Compare Similar Items

Show Difference

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Invitrogen

44-568-G

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Antigen:
Phospho-GAB1 (Tyr627)

Classification:
Polyclonal

Formulation:
Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3

Gene Accession No.:
Q13480, Q9QYY0

Gene Symbols:
GAB1

Immunogen:
The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human Gab1 that contains tyrosine 627. The sequence is conserved in mouse.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
GAB1

Gene Alias:
AA408973; AW107238; EGK_16125; GAB1; GRB2 associated binding protein 1; GRB2-associated binder 1; GRB2-associated binding protein 1; GRB2-associated binding protein 1 long isoform; GRB2-associated-binding protein 1; Growth factor receptor bound protein 2-associated protein 1; OTTHUMP00000220263

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14388, 2549

Content And Storage:
-20°C

Form:
Liquid

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Invitrogen™

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Antigen:
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Classification:
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Formulation:
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Gene Accession No.:
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Gene Symbols:
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Immunogen:
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Quantity:
960 assays

Primary or Secondary:
__

Target Species:
__

Product Type:
Neuraminidase Assay

Isotype:
__

Applications:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
This kit contains NA-Fluor™ MUNANA Substrate (4-(methylumbelliferyl)-N-acetylneuraminic acid), NA-Fluor™ 2X Assay Buffer, and NA-Fluor™ Stop Solution. Store the substrate at -20°C in the dark. Other components can be stored at 2 to 8°C. Enough reagent for ten 96-well microplate assays is supplied.

Form:
Lyophilized

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Antigen:
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Classification:
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Formulation:
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Gene Accession No.:
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Gene Symbols:
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Immunogen:
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Quantity:
5 nmol

Primary or Secondary:
__

Target Species:
__

Product Type:
siRNA

Isotype:
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Applications:
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Conjugate:
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Gene:
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Gene Alias:
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Host Species:
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Purification Method:
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Regulatory Status:
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Gene ID (Entrez):
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Content And Storage:
The siRNA (annealed) is shipped at ambient temperature as dried down oligonucleotides in a single tube, along with 1.75 ml Nuclease-free Water for resuspension. Store at or below –20°C.

Form:
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Fischer Scientific

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Antigen:
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Classification:
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Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
5 nmol

Primary or Secondary:
__

Target Species:
__

Product Type:
siRNA

Isotype:
__

Applications:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
The siRNA (annealed) is shipped at ambient temperature as dried down oligonucleotides in a single tube, along with 1.75 ml Nuclease-free Water for resuspension. Store at or below –20°C.

Form:
__